PSA levels at 6, 12, and 24 weeks post-randomization correlate with 96-month survival in prostate cancer
Low PSA at 24 weeks predicts longer survival in prostate cancer
This post-hoc analysis of five phase 3 trials in 7129 patients with prostate cancer found that 96-month overall survival varied by metastati…
Men with prostate cancer who hit a PSA level of 0.2 ng/mL or less within 24 weeks of starting treatment are far more likely to survive at le…
Adding adrenaline to bupivacaine for lipoma plane block reduces blood loss and pain
Adrenaline in local blocks reduces pain and bleeding during lipoma surgery
This prospective randomized trial in 40 adults undergoing lipoma excision found that adding adrenaline (1:200,000) to bupivacaine for ultras…
Adding adrenaline to a local anesthetic block lessened pain and bleeding for patients having lipoma removal, based on a trial of 40 adults.
Pilot study explores ketogenic diet effects on symptoms in adults with generalized myasthenia gravis
Ketogenic diet may improve daily function in myasthenia gravis
This randomized, controlled, open-label pilot study examined whether a ketogenic diet improves functional status and quality of life in adul…
A small pilot trial hints that a keto diet could ease daily struggles for people with myasthenia gravis, but larger studies are needed.
Mecapegfilgrastim reduces grade 3+ neutropenia in treatment-naive diffuse large B-cell lymphoma patients versus no prophylaxis
New Drug Cuts Severe Infection Risk In Lymphoma Care
This randomized controlled trial evaluated mecapegfilgrastim in 42 treatment-naive patients with diffuse large B-cell lymphoma.
A new long-acting injection lowers the risk of dangerous low white blood cell counts in lymphoma patients starting their first round of chem…
Digital collaboration with patient representatives reduces travel costs and effort in psycho-oncology research
Digital collaboration reduces costs and barriers for cancer patients
This qualitative study involved 5 patient representatives from the Reduct trial.
A small qualitative study suggests digital tools may lower travel costs and improve flexibility for cancer patients, though technical and co…
Lyophilized pegaspargase shows similar activity to liquid form in pediatric ALL
Lyophilized pegaspargase shows similar activity and safety to liquid form for pediatric leukemia patients
This phase 2 study in 89 pediatric ALL patients in Russia found that lyophilized pegaspargase had similar maximum plasma asparaginase activi…
A new form of pegaspargase works just like the liquid version for treating acute lymphoblastic leukemia in children in Russia.
Systematic review of 17 studies shows advanced Monte Carlo strategies outperform or match conventional algorithms in clinical linear accelerators
Radiation therapy just got far more precise
This systematic review synthesizes evidence from 17 eligible studies across Varian-, Elekta-, and Siemens-associated platforms evaluating ad…
Radiation therapy is becoming far more precise, thanks to faster simulations that model how energy travels through the body with unmatched a…
Case report and literature review of thymoma associated with stiff person syndrome and myasthenia gravis
A Rare Muscle Stiffness Link to Thymoma Tumor Explained
This case report and literature review examines the association between thymoma and autoimmune syndromes including stiff person syndrome and…
A rare mix of muscle stiffness and weakness was traced to a thymoma tumor, with new genetic clues pointing to a shared immune cause.
Meta-analysis of artificial intelligence models for predicting prostate cancer outcomes
AI Predicts Prostate Cancer Outcomes With 80 Percent Accuracy
This meta-analysis evaluated 85 studies regarding the performance of artificial intelligence models in predicting various prostate cancer ou…
New AI tools can predict prostate cancer outcomes with over 80 percent accuracy, helping men and their doctors make better treatment decisio…
Cryoablation may offer greater tumor reduction and fewer adverse events than HIFU for breast fibroadenoma
Two painless options shrink breast lumps with different tradeoffs
A meta-analysis of prospective single-arm studies compared high-intensity focused ultrasound (HIFU) and cryoablation for breast fibroadenoma…
Freezing breast lumps removes more tissue than heat but causes slightly more skin irritation in these new findings
Phase II trial of oral pamiparib in recurrent ovarian cancer after prior PARPi exposure
Pamiparib alone offers limited hope for ovarian cancer patients who have already tried other drugs
This prospective Phase II clinical trial enrolled 15 patients with recurrent ovarian cancer after prior PARPi exposure.
New data shows taking pamiparib by itself works for only a small number of women with recurrent ovarian cancer after other treatments failed
Meta-analysis finds frozen section reliable for tumor-free margins in OSCC
Surgeons rely on frozen sections to ensure clean cuts for oral cancer patients
This systematic review and meta-analysis of 19 studies (9 with complete data) assessed frozen section analysis for detecting tumor-free marg…
A new review confirms that frozen section analysis is a highly reliable way for surgeons to check if oral cancer has been fully removed duri…