Metachronous pancreatic metastasis from ovarian cancer is rare, mostly high-grade serous
Ovarian cancer can spread to pancreas, rare review finds
This systematic review of 7 studies (8 cases) found that metachronous pancreatic metastasis from ovarian cancer is rare and most often origi…
A rare spread of ovarian cancer to the pancreas may be treatable with surgery or chemo, but evidence is thin.
Immune Health Index serves as a protective prognostic factor in post-resection hepatocellular carcinoma
New immune health index helps predict liver cancer outcomes
This meta-analysis evaluates the Immune Health Index (IHI) and its clinical version (cIHI_v8) for prognostic stratification in patients with…
A new tool called the Immune Health Index helps doctors predict how well patients with liver cancer might respond to immunotherapy.
Probiotic preparations show potential to alleviate chemotherapy-induced oral mucositis severity through immunomodulation and metabolic regulation
Probiotics show potential to reduce chemotherapy induced mouth sores
This systematic review evaluates the role of probiotic preparations in managing chemotherapy-induced oral mucositis (CIOM). The authors conc…
Chemotherapy can cause painful mouth sores. New research suggests that probiotic treatments might help manage these symptoms and protect the…
Single-port robotic-assisted radical prostatectomy provides comparable oncological outcomes to multi-port techniques with improved recovery
Single port surgery offers faster recovery for prostate cancer patients
This umbrella review of meta-analyses indicates that single-port robotic-assisted radical prostatectomy (SP-RARP) offers shorter hospital st…
A single-port robotic surgery for prostate cancer can lead to shorter hospital stays and less pain without affecting long-term cancer outcom…
Ductoscopy failure rate 10% across 25 studies; perforation and stenosis are top causes
New Framework Aims to Reduce Failures in Breast Ductoscopy
This meta-analysis of 25 studies (2,853 procedures) found a pooled ductoscopy failure rate of 10.0% (95% CI 6.8%–13.7%). The most common cau…
A new classification system aims to help doctors identify and manage complex challenges during breast ductoscopy procedures.
Robotic low anterior resection reduces conversion rates but increases operative time compared to laparoscopic surgery
Robotic Surgery Shows Lower Conversion Rates for Rectal Cancer
This meta-analysis compares totally robotic low anterior resection (TR-LAR) with conventional laparoscopic low anterior resection (L-LAR) fo…
A review of surgical techniques shows that robotic-assisted procedures may lower the need to switch to open surgery for rectal cancer patien…
Integrin β1 emerges as underexplored regulator of medulloblastoma progression and therapy resistance
Brain Tumor Cells May Use a Protein to Resist Treatment
This mini-review examines the role of Integrin β1 signaling in medulloblastoma, highlighting its involvement in cell-extracellular matrix in…
A protein called integrin β1 may help medulloblastoma resist therapy. New review explores its role.
Patient-led home-based follow-up reduces hospital contacts by 38% in colorectal cancer survivors
Patient Led Follow Up Reduces Hospital Visits for Cancer Survivors
This cluster randomized trial of 354 stage I-III colorectal cancer survivors found that patient-led, home-based follow-up (PHFU) reduced hos…
A new home based follow up program may reduce hospital visits by 38% for people who have survived colorectal cancer surgery.
Ciltacabtagene autoleucel is associated with higher non-ICANS neurologic toxicity rates than idecabtagene vicleucel
Trial shows specific risks for some patients with multiple myeloma
This meta-analysis of 4,630 patients evaluates non-ICANS neurologic toxicities (NINTs) following BCMA-directed CAR-T therapy in multiple mye…
New data reveals that one type of CAR-T cell therapy carries a higher risk of nerve issues than others for patients with multiple myeloma.
Circulating miRNAs show high diagnostic accuracy for oral squamous cell carcinoma with AUC of approximately 0.90
Saliva and blood tests may help identify oral cancer
This systematic review and meta-analysis evaluated the diagnostic accuracy of circulating microRNAs in blood and saliva for oral squamous ce…
New data suggests that specific molecules in saliva and blood could help doctors more accurately identify patients with oral squamous cell c…
Tamoxifen improves distant recurrence-free interval for postmenopausal women with specific tumor microenvironment scores
Tumor environment markers may predict how well tamoxifen works
This secondary analysis of a randomized trial involving 513 postmenopausal women with ER+HER2- breast cancer found that tamoxifen improved t…
New analysis suggests that specific immune and cell types within a tumor could help predict if tamoxifen will be effective for certain breas…
Dostarlimab and Niraparib Combination Improves Progression Free Survival in Advanced Endometrial Cancer
Adding Niraparib to Dostarlimab Delays Endometrial Cancer Worsening
A Phase 3 trial shows that adding niraparib to dostarlimab maintenance significantly extends progression-free survival for patients with adv…
A phase 3 trial found that adding niraparib to dostarlimab after chemo slowed cancer growth in advanced endometrial cancer, but did not exte…