FDA Approves Xpovio (selinexor) for Multiple Myeloma and DLBCL
FDA approves new drug Xpovio for certain blood cancers.
The FDA approved Xpovio (selinexor) for multiple myeloma in combination with bortezomib and dexamethasone after at least one prior therapy, …
The FDA approved Xpovio (selinexor) for multiple myeloma and a type of lymphoma called DLBCL. It offers a new option for patients who have t…
Bayesian network meta-analysis shows AI-assisted colonoscopy improves adenoma detection in adults
AI Boosts Colon Cancer Detection, But Not All Systems Are Equal
This Bayesian network meta-analysis evaluated artificial intelligence-assisted colonoscopy versus standard colonoscopy in 34 106 adults. The…
AI-assisted colonoscopy finds more precancerous polyps than standard exams, but the four leading systems show only small differences in perf…
Narrative review discusses CAR-T and HSC therapies for cancer and autoimmune conditions
Cancer Cell Therapy Gets Second Life Against Diabetes and MS
This narrative review examines the scope of chimeric antigen receptor T-cell (CAR-T), CAR-engineered regulatory T cell (CAR-Treg), and hemat…
• CAR-T cells trained to calm overactive immune systems show real promise • People with Type 1 diabetes or multiple sclerosis could benefit …
Narrative review links chronic hemozoin exposure to prostate cancer development in malaria regions
Malaria Byproduct May Fuel Prostate Cancer Growth
This narrative review explores the hypothesis that chronic exposure to hemozoin from malaria may contribute to prostate cancer development. …
A byproduct left behind by malaria parasites may fuel prostate cancer by keeping the immune system in a constant state of low-grade inflamma…
Integrative therapy with traditional Chinese medicine reduces adverse events and improves immune markers in postoperative ovarian cancer patients receiving platinum-based chemotherapy
Adding This One Step After Surgery May Reduce Chemo Side Effects
A systematic review and meta-analysis of 1,719 patients found that adding traditional Chinese medicine to platinum-based chemotherapy signif…
Women who added traditional Chinese medicine to their post-surgery chemo saw nearly 50 percent fewer side effects and stronger immune recove…
Experimental agents show response rates up to 70% in relapsed or refractory diffuse large B-cell lymphoma
New cancer therapies double response rates for tough lymphoma
This systematic review and meta-analysis of phase 1-2 trials evaluated experimental agents alone or combined with CD20-antibodies in adults …
Patients with aggressive lymphoma once had few options after standard treatments failed, but new therapies are changing that outlook in ways…
Combining pegylated interferon with nilotinib improves early molecular response in newly diagnosed chronic phase chronic myeloid leukaemia
Adding a weekly shot to a daily leukemia pill boosts deep remission rates
This phase 3 trial compared nilotinib monotherapy against nilotinib combined with pegylated interferon alfa-2a in patients with newly diagno…
A weekly injection added to a daily pill helped more newly diagnosed CML patients reach deep remission, but it also caused more side effects…
Preoperative indicators predict microvascular invasion in hepatocellular carcinoma patients
New Model Predicts Liver Cancer Spread Before Surgery
This meta-analysis evaluated preoperative indicators including alpha-fetoprotein, tumor size, and tumor margin to predict microvascular inva…
A simple scoring tool now predicts if liver cancer has spread into tiny blood vessels, helping surgeons plan safer operations and improve su…
Meta-analysis of surgical resection for lung neuroendocrine tumors
Sparing Lung Tissue May Save Lives Without Hurting Survival Rates
This meta-analysis of six studies compared lobectomy to sub-lobar resection for lung neuroendocrine tumors. It found no significant differen…
New research shows taking less lung tissue during surgery for rare tumors gives patients the same long-term survival chance as taking more.
Systematic review and meta-analysis compares intravesical gemcitabine/docetaxel versus BCG for non-muscle-invasive bladder cancer
Gemcitabine and docetaxel show similar recurrence-free survival to BCG for bladder cancer
This systematic review and meta-analysis evaluated intravesical gemcitabine and docetaxel compared with Bacillus Calmette-Guérin (BCG) in pa…
A meta-analysis of 1634 patients found gemcitabine and docetaxel offered recurrence-free survival rates comparable to BCG therapy for non-mu…
Narrative review suggests phytochemicals and phages may augment conventional antibiotics for brucellosis
New plant-based and phage options might help treat stubborn brucellosis infections in people and animals
This narrative review discusses novel strategies for treating brucellosis in humans and animals. The authors note that conventional antibiot…
Standard antibiotics sometimes fail to cure brucellosis, and bacteria are becoming resistant. New methods using plant chemicals and viruses …
Scoping review links housing insecurity and indoor pollutants to increased cancer risk and reduced survival
Your Home Safety Could Be The Key To Lowering Cancer Risk Today
This scoping review examines populations exposed to housing and energy insecurity, including women and low-income households. The authors sy…
Living in unsafe homes with poor air quality and energy poverty makes cancer more likely and harder to beat for many people.