Tucatinib plus trastuzumab and pertuzumab improves median PFS to 24.9 months in HER2+ MBC
Trial shows Tucatinib improves progression-free survival for metastatic breast cancer
This Phase III randomized controlled trial of 654 patients with HER2+ metastatic breast cancer found that adding tucatinib to trastuzumab an…
Adding tucatinib to a standard two-drug combination may help patients with HER2+ metastatic breast cancer live longer without their disease …
AZA or LDAC combined with venetoclax likely improves mortality, remission, and quality of life
New combinations show promise for older adults with myeloid leukemia
This systematic review and meta-analysis of 47 studies evaluated treatments for older adults with AML ineligible for conventional chemothera…
Combining specific drugs like venetoclax with other treatments may improve survival and quality of life for older adults with acute myeloid …
Signet ring morphology in gastric biopsies may mask metastatic invasive lobular carcinoma from breast cancer
Expert Review Helps Identify Breast Cancer Spreading to Stomach
This case report describes a 52-year-old woman with metastatic invasive lobular carcinoma that was initially misidentified as primary gastri…
A single patient's case shows how specific lab tests can help doctors distinguish between stomach cancer and metastatic breast cancer.
Hepatic MPNST without NF1: normal tumor markers, no recurrence 2 years after resection
Case Report Shows Surgery for Rare Liver Tumor Success
A case report and literature review describes a 56-year-old woman with hepatic malignant peripheral nerve sheath tumor (MPNST) without neuro…
A rare liver tumor known as MPNST was successfully treated with surgery, showing no signs of return after two years.
PGA sheets plus fibrin glue reduce delayed bleeding risk after gastric endoscopic submucosal dissection
Fibrin Glue and PGA Sheets Reduce Bleeding After Gastric Surgery
This meta-analysis of randomized and observational studies involving 2,728 patients found that the combination of polyglycolic acid (PGA) sh…
A combination of fibrin glue and PGA sheets may significantly reduce the risk of delayed bleeding for patients undergoing gastric endoscopic…
Epigallocatechin-3-gallate shows positive therapeutic effects on various digestive system diseases in animal models
Green tea compound shows potential for several digestive diseases
This meta-analysis of 63 preclinical studies involving 738 animals indicates that Epigallocatechin-3-gallate (EGCG) has a positive therapeut…
A review of animal studies suggests a green tea compound could help treat various cancers and digestive conditions.
Combined pelvic and para-aortic lymphadenectomy improves overall survival compared to no lymphadenectomy in endometrial cancer
Combined lymphadenectomy may improve survival for endometrial cancer patients
This meta-analysis of 25,432 patients found that combined pelvic and para-aortic lymphadenectomy (PPaLND) is associated with significant imp…
A large review of over 25,000 cases suggests that a more extensive surgical removal of lymph nodes can improve survival in some endometrial …
Postoperative lymphocele affects 30% of gynecologic cancer patients after lymph node dissection
20 Risk Factors for Lymphocele After Gynecologic Cancer Surgery
This meta-analysis of 15739 patients undergoing lymph node dissection for gynecological malignant tumors found a pooled postoperative lympho…
Nearly 1 in 3 women develop lymphocele after lymph node dissection for gynecologic cancer. New analysis reveals top risk factors.
Orthotopic neobladder techniques show comparable functional outcomes in bladder cancer
Best bladder reconstruction technique? New analysis compares 14 options
This network meta-analysis of 1,129 patients compared 14 orthotopic neobladder reconstruction techniques after radical cystectomy for bladde…
A new analysis of 14 bladder reconstruction techniques finds most perform similarly, but some may offer better continence or urine flow.
Robotic cholecystectomy shows fewer complications and shorter hospital stay for gallbladder cancer
Robotic Surgery for Gallbladder Cancer Shows Benefits
A meta-analysis of propensity-score-matched studies compared robotic versus open radical cholecystectomy for gallbladder cancer. Robotic sur…
Robotic surgery for gallbladder cancer may lead to fewer complications, less blood loss, and shorter hospital stays compared to open surgery…
TRAM MRI shows 0.89 AUC for differentiating treatment response from radionecrosis in CNS tumors
New MRI mapping helps tell tumor growth from radiation damage
This diagnostic meta-analysis of 286 patients with CNS tumors treated with radiotherapy found that treatment response assessment maps (TRAMs…
Doctors can now better distinguish between shrinking tumors and tissue damage caused by radiation using a specific MRI mapping tool.
EMR integrated platform improves data abstraction efficiency and speed for cancer patient records
New digital platform speeds up cancer data collection and entry
Researchers evaluated an EMR-integrated platform designed to automate data extraction from cancer patient records. The study found that the …
A new software tool cut the time needed to record cancer treatment details by nearly half, helping medical teams work faster.