Benmelstobart plus anlotinib improves progression-free survival versus pembrolizumab plus placebo in first-line PD-L1-positive advanced NSCLC
New drug combo may extend time before cancer grows in lung patients
This randomised, controlled, phase 3 trial evaluated benmelstobart plus anlotinib versus pembrolizumab plus placebo in patients with PD-L1-p…
A new drug combo may extend the time before cancer grows in lung patients who have not yet received treatment for their advanced disease.
Lu-PSMA-617 reduces disease progression versus deferred ADT in oligometastatic HSPC in phase 2 trial
Can a targeted radiation drug delay prostate cancer progression without hormone therapy?
A phase 2 randomized controlled trial of 58 men with biochemically recurrent oligometastatic hormone-sensitive prostate cancer found Lu-PSMA…
A targeted radiation drug delayed prostate cancer progression by 20 months in early-stage patients without requiring hormone therapy first.
PARPi combinations show no significant clinical improvement in adult patients with glioblastoma
PARPi drugs show limited benefit for glioblastoma due to brain barriers
This systematic review evaluated poly-ADP-ribose polymerase inhibitors (PARPi) combined with standard therapy for adult patients with gliobl…
A systematic review examined PARP inhibitors used with standard treatments for adult glioblastoma patients.
DIBH reduces radiation dose to heart and lungs in left-sided breast cancer VMAT
Breath-hold technique reduces radiation dose to heart during breast cancer treatment
A meta-analysis of 11 studies in left-sided breast cancer patients treated with VMAT found deep inspiration breath hold (DIBH) reduced mean …
Holding a deep breath during radiation therapy consistently lowers the dose to the heart, lungs, and other organs for left-sided breast canc…
Multiphasic CT-based deep learning model predicts early HCC recurrence after liver transplantation
New AI model shows promise for predicting early liver cancer recurrence after transplant
This retrospective cohort study evaluated a multiphasic CT-based multimodal deep learning (MD DL) model in 147 liver transplant recipients.
A new AI tool using CT scans and lab data predicts early liver cancer return after transplant with high accuracy in past patient records.
Subcutaneous amivantamab shows shorter administration time and fewer infusion reactions in advanced solid tumors
Could a simple injection replace hours-long cancer infusions?
A phase Ib clinical trial in 158 patients with advanced solid malignancies evaluated subcutaneous amivantamab administration.
A new injection method for advanced cancer treatment cuts administration time to under 10 minutes and reduces severe side effects compared t…
Radiomics models predict IDH mutation status and survival in glioma patients across discovery and validation cohorts
Can scans predict glioma risks without surgery? New models show promise but need more proof
This multicenter cohort study evaluated radiomics-based machine learning models in 638 glioma patients to predict isocitrate dehydrogenase (…
Computer scans can spot dangerous brain tumor patterns without surgery, but accuracy drops when tested on new patients, so doctors still nee…
CADe Systems Show Variable Improvements in Adenoma Detection During Colonoscopy in Meta-Analysis
AI tools help doctors spot more colon polyps during routine colonoscopies
A systematic review and network meta-analysis of 48 RCTs involving 38,986 patients found that computer-aided detection (CADe) systems improv…
New AI tools help doctors spot more colon polyps during routine colonoscopies, potentially lowering the chance of missing small, flat growth…
Meta-analysis finds HMA plus venetoclax yields 66% CR/CRi rate in younger, fit AML patients
Analysis finds promising results for leukemia treatment in younger patients
A meta-analysis of 429 younger, fit AML patients found HMA plus venetoclax yielded a 66% CR/CRi rate and 75% 1-year OS.
Younger acute myeloid leukemia patients treated with a specific drug combination achieved 75% one-year survival and 66% complete remission r…
Qigong shows large effect on subjective cognitive function in cancer survivors in meta-analysis
Can gentle movement help cancer survivors struggling with brain fog?
A systematic review and meta-analysis of 16 studies in cancer survivors found qigong significantly improved subjective cognitive function ve…
Cancer survivors struggling with brain fog may feel clearer after practicing qigong, a gentle mix of movement and breathing that showed stro…
Interactive e-books and traditional education show comparable effectiveness for foundational cancer sleep management nurse training
Study compares e-book and traditional training for nurses on cancer sleep management
A cluster randomized controlled trial of 142 oncology nurses found both interactive e-books and traditional education significantly improved…
Interactive e-books and traditional classes both boosted nurses' confidence in helping cancer patients with sleep issues, though knowledge g…
Ex vivo diffusion MRI characterizes tissue components in post-neoadjuvant rectal cancer specimens
Can a new MRI scan spot hidden rectal cancer after treatment?
An ex vivo imaging study of 5 fixed post-neoadjuvant therapy rectal cancer specimens found that diffusion MRI metrics (fractional anisotropy…
A new high-resolution MRI scan can spot hidden rectal cancer by measuring subtle water movement differences in treated tissue samples.