Hospitalized malignant neoplasm patients show high comorbidity burden and distinct disease patterns across 163 Chinese hospitals
Hospitalized cancer patients in China often have other serious health conditions
This retrospective cohort study examined 107,029 hospitalized patients with malignant neoplasms across 163 hospitals in Zhanjiang, China.
Hospitalized cancer patients in China often face five other serious health conditions, with rural residents, men, and those aged 65 or older…
Radiomics and AI show promise for cervical cancer radiotherapy but face validation and standardization challenges
AI tools show promise for cervical cancer radiotherapy but need more testing
This narrative review examines the application of radiomics and artificial intelligence (AI) in precision radiotherapy for women with cervic…
AI tools show promise for cervical cancer radiotherapy but need more testing before becoming standard care for patients.
Radiotherapy associated with improved response and survival in HCC patients receiving immune-targeted therapy
Does adding radiation help some liver cancer patients respond better to their immune therapy?
A multicenter retrospective study of 238 HCC patients receiving immune-targeted therapy found radiotherapy was associated with higher object…
Adding radiation to immune therapy helped more advanced liver cancer patients see their tumors shrink and live longer compared to those who …
Pyroptosis-related gene signature predicts prognosis in triple-negative breast cancer patients
Can a gene signature predict survival for triple-negative breast cancer patients?
This observational cohort study analyzed data from TCGA and GEO databases, validated in an independent GEO cohort and 48 clinical samples, t…
A genetic warning system in triple-negative breast cancer tumors can predict which patients face a higher risk of the cancer returning.
Sedentary time, insomnia, and weight linked to high-risk thyroid nodules in retrospective cohort
Does sitting too much or poor sleep raise your risk for dangerous thyroid nodules?
A retrospective cohort study of 164 patients with thyroid nodules found that sedentary time >2 hours/day, insomnia, and elevated weight were…
Sitting too much, poor sleep, and higher weight raise the risk for dangerous thyroid nodules, while eating a diverse diet and smaller nodule…
Epigenomic ctDNA profiling identifies PDAC subtypes and improves prognostication over tissue-based methods in metastatic disease
Can a blood test predict pancreatic cancer subtypes better than tissue samples?
This multi-institutional cohort study evaluated epigenomic profiling of circulating tumor DNA (ctDNA) for subtyping pancreatic ductal adenoc…
A new blood test matches tissue samples and predicts patient outcomes better for metastatic pancreatic cancer, offering a hopeful step towar…
Feasibility of combining ESPEN guidelines and Ayurvedic concepts to personalize diets for cancer patients
A small feasibility study found combining Ayurveda and standard guidelines is possible for cancer patients
This feasibility study evaluated personalized meal plans in 33 consenting adult cancer patients over 4 weeks to 6 months.
Personalized meals blending Ayurveda and standard cancer guidelines improved diet quantity for 33 adult cancer patients with no safety conce…
Higher county-level socio-behavioral risk associated with increased breast and prostate cancer mortality in U.S. counties
County social factors linked to higher breast and prostate cancer death rates within racial groups
This cross-sectional review analyzed 3,141 U.S.
County-level social factors like education and housing link to higher breast and prostate cancer death rates within all racial groups studie…
FDA Approves Keytruda (pembrolizumab) for Treatment of Unresectable or Metastatic Melanoma
FDA approves new drug Keytruda for advanced skin cancer
The FDA has approved Keytruda, a PD-1-blocking antibody, for the treatment of patients with unresectable or metastatic melanoma.
FDA approves Keytruda to treat advanced skin cancer that cannot be removed by surgery or has spread to other parts of the body.
Systematic review examines HIF-1α role in digestive system inflammation and cancer
Could a single protein be fueling both gut inflammation and cancer?
A systematic review synthesizing existing literature found HIF-1α contributes to pathogenesis of inflammatory digestive diseases and promote…
A single protein called HIF-1α may be driving both gut inflammation and digestive cancers while helping tumors resist drugs and evade the im…
Case report: Orelabrutinib-rituximab with intravitreal methotrexate shows response in primary vitreoretinal lymphoma
Can a new drug combination help treat a rare eye cancer?
A case report with literature review describes one patient with primary vitreoretinal lymphoma (PVRL) treated with orelabrutinib and rituxim…
A new drug combination improved vision and controlled tumors in a patient with a rare eye cancer, with no reported side effects.
Case report describes complete remission in PDTC with combined radiotherapy and chemotherapy
Case report describes complete remission in advanced thyroid cancer patient after combined treatment
A case report and literature review examined a 55-year-old male with advanced poorly differentiated thyroid carcinoma (PDTC).
A 55-year-old man with advanced thyroid cancer achieved complete remission after combining local radiotherapy and intravenous chemotherapy.