Case report on asciminib plus ponatinib or axitinib in CML relapse with B lymphoblastic blast crisis
New combo drug stops leukemia that fought back against two drugs
This case report describes a single CML patient who relapsed with B lymphoblastic blast crisis harboring a T315I mutation and a novel e6a3 B…
A new three-drug mix stops a tough leukemia that grew stronger after two drugs failed to control it.
Deep learning models for microsatellite instability screening in low-resource settings
Smart AI Helps Spot Cancer Risks in Low-Resource Clinics
This preclinical computational study evaluated deep learning models for microsatellite instability classification in colorectal cancer histo…
A new, simple AI tool can spot a specific cancer risk in patients with limited access to advanced labs.
Preclinical report suggests combined ARSB and pembrolizumab inhibits melanoma progression in mice
Mouse model shows combined ARSB and pembrolizumab slows melanoma growth
This preclinical report evaluates the combination of recombinant human Arylsulfatase B (ARB) and pembrolizumab in a B16F10 syngeneic mouse m…
In a lab mouse model, combining a specific enzyme with pembrolizumab slowed tumor growth and improved survival, offering early clues for fut…
Narrative review reports Onca model performance on pancreatic cancer tasks versus other LLMs
New AI tool helps doctors find pancreatic cancer trials faster
This narrative review and model development report evaluates an open 9B dense language model, Onca, against four comparators for pancreatic …
A new AI tool helps doctors quickly match patients with pancreatic cancer trials using open data.
Conference report on AI ensemble for histopathological classification of ovarian carcinoma subtypes
AI Can Now Tell Apart Two Ovarian Cancers That Look Nearly Identical
This conference report describes a preclinical computational study using an attention-guided CNN ensemble to classify high-grade versus low-…
This technology could prevent misdiagnosis and ensure patients get the most effective treatment for their specific cancer type from day one.
Tumor debulking plus chemotherapy did not improve overall survival in multiorgan metastatic colorectal cancer patients
Surgery Doesn’t Extend Life for Advanced Colon Cancer
This randomized clinical trial enrolled 382 adult patients with multiorgan metastatic colorectal cancer across 27 hospitals in the Netherlan…
This large study shows that removing tumors in advanced colon cancer doesn’t help people live longer.
Phase III trial indicates ultra-low-dose nivolumab may improve survival over chemotherapy in advanced solid tumors
A Tiny Dose of This Cancer Drug Is Outperforming Chemo
This Phase III randomized trial evaluated ultra-low-dose nivolumab against standard chemotherapy in patients with advanced solid tumors prog…
Giving a much smaller dose of a powerful cancer drug can extend life with fewer side effects, making treatment more tolerable and accessible…
Pembrolizumab Plus Paclitaxel Improves Survival in Recurrent Ovarian Carcinoma Compared to Paclitaxel Alone
New Drug Combo Extends Survival for Tough Ovarian Cancer
This randomised, double-blind phase 3 study evaluated pembrolizumab plus paclitaxel versus placebo plus paclitaxel in 643 female participant…
This new combination offers a meaningful survival boost for women with recurrent ovarian cancer that has become resistant to standard treatm…
Transdermal Estradiol Patches Show Noninferiority to LHRH Agonists in Prostate Cancer Metastasis-Free Survival
Men with advanced prostate cancer may have fewer hot flashes with a new patch treatment
This phase 3 randomized trial evaluated 1360 men with locally advanced prostate cancer across 75 U.K.
A new patch for advanced prostate cancer showed similar cancer control to standard shots but caused fewer hot flashes in a large UK trial.
Meta-analysis finds mHealth reduces infections and PICC complications in pediatric cancer
Mobile Apps Cut Infection Risk for Children With Cancer
This systematic review and meta-analysis of 2645 pediatric cancer patients found that mHealth interventions significantly reduced infection …
Using phone apps helps children with cancer stay safer and feel better during treatment.
Neoadjuvant Chemoimmunotherapy Alters Tumor Microenvironment in Esophageal Cancer
Combination therapy may help overcome resistance in esophageal cancer
This Phase 3 RCT in 55 patients with locally advanced esophageal squamous cell carcinoma compared neoadjuvant chemotherapy alone versus comb…
A small trial suggests combination therapy might help overcome resistance in esophageal cancer by targeting specific immune cells.
Nivolumab plus ipilimumab versus nivolumab in advanced neuroendocrine carcinoma phase II trial
New Combo Shows Modest Promise for Hard-to-Treat Neuroendocrine Cancers
This randomized phase II trial enrolled 185 patients with advanced neuroendocrine carcinoma refractory to platinum-based chemotherapy.
For patients with rare, aggressive neuroendocrine cancers that resist initial treatment, this study offers a new, though modest, combination…