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Oncology

858 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
27648 patients shows robotic TME improves specimen quality and margin safety for rectal cancer cases
Oncology Meta-analysis
27648 patients shows robotic TME improves specimen quality and margin safety for rectal cancer cases Robotic surgery shows better tissue removal for some rectal cancer patients
A large meta-analysis involving 27,648 patients undergoing total mesorectal excision for rectal cancer indicates that robotic surgery yields…
A large review found robotic surgery often removed more complete tissue samples for rectal cancer patients compared to standard laparoscopic…
Carer psychological distress linked to worse patient mental health and higher service use in cancer care
Oncology Meta-analysis
Carer psychological distress linked to worse patient mental health and higher service use in cancer care Distressed carers often care for patients with similar mental health struggles
This systematic review and meta-analysis of 169 studies found that carers with distress, depression, or anxiety were significantly more like…
When family carers feel anxious or depressed, their patients often face worse mental health and more emergency visits. This review of 169 st…
Repeat microsurgery for recurrent vestibular schwannoma achieves gross total resection but increases facial nerve deterioration risk to 43%
Oncology Meta-analysis
Repeat microsurgery for recurrent vestibular schwannoma achieves gross total resection but increases facial nerve deterioration risk to 43% Repeat surgery for recurrent tumors offers control but higher risks than first surgery
This systematic review and meta-analysis evaluates repeat microsurgical resection versus primary surgery in 359 patients with recurrent vest…
A review of 359 patients found repeat surgery controls recurrent tumors well but carries higher risks of nerve damage and fluid leaks compar…
WeChat-based patient-doctor interaction improves patient experience in H. pylori infection treatment
Oncology RCT
WeChat-based patient-doctor interaction improves patient experience in H. pylori infection treatment A WeChat chat group did not improve stomach bug cure rates compared to standard care
This randomized controlled trial evaluated a WeChat-based patient-doctor interaction system versus routine patient education in treatment-na…
A chat group with doctors did not cure more stomach bugs than standard education, though patients felt better using the app.
Gut microbiome factors and dietary modulation may optimize triple-negative breast cancer management
Oncology Sys. Review
Gut microbiome factors and dietary modulation may optimize triple-negative breast cancer management Gut bacteria and diet may hold new keys for triple-negative breast cancer care
This narrative review examines the role of gut microbiome composition, antibiotics, obesity, and dietary modulation in triple-negative breas…
A review explores how gut bacteria, antibiotics, and diet could change treatment for triple-negative breast cancer patients.
Weight reduction ranked highest for limb volume, while VR-based training ranked highest for pain in breast cancer-related lymphedema
Oncology Meta-analysis
Weight reduction ranked highest for limb volume, while VR-based training ranked highest for pain in breast cancer-related lymphedema Weight loss and virtual reality rank highest for breast cancer swelling and pain relief
This network meta-analysis of 754 patients evaluated non-pharmacological therapies for breast cancer-related lymphedema. Weight reduction ra…
Weight loss and virtual reality training ranked best for reducing arm swelling and pain in breast cancer patients, though other therapies al…
FDA Approves Jylamvo (methotrexate) for Multiple Neoplastic and Inflammatory Indications
Oncology FDA Approval
FDA Approves Jylamvo (methotrexate) for Multiple Neoplastic and Inflammatory Indications FDA approves Jylamvo, a liquid methotrexate for cancer and arthritis.
The FDA approved Jylamvo (methotrexate) oral solution for acute lymphoblastic leukemia, mycosis fungoides, non-Hodgkin lymphoma, rheumatoid …
The FDA approved Jylamvo (methotrexate) oral solution for several cancers and inflammatory conditions. It treats certain leukemias, lymphoma…
Adding WBRT to SRS cuts brain metastasis recurrence but raises cognitive decline without survival gain
Oncology Meta-analysis
Adding WBRT to SRS cuts brain metastasis recurrence but raises cognitive decline without survival gain Adding whole-brain radiation to SRS lowers recurrence but does not extend life for brain metastases patients
This meta-analysis of 1,757 patients with brain metastases found that adding whole-brain radiotherapy (WBRT) to stereotactic radiosurgery (S…
Combining SRS with whole-brain radiation lowers tumor recurrence but does not improve survival compared to SRS alone for patients with brain…
Minimally invasive cystectomy reduces blood loss and transfusions but extends operative time
Oncology Sys. Review
Minimally invasive cystectomy reduces blood loss and transfusions but extends operative time Minimally invasive bladder cancer surgery cuts blood loss and speeds recovery compared to open operations
This systematic review and network meta-analysis of 1270 patients with bladder cancer compared open, laparoscopic, and robot-assisted radica…
A new analysis of 1270 patients shows minimally invasive bladder cancer surgery reduces blood loss and complications compared to open operat…
Immune checkpoint blockade shows promise but faces resistance challenges in nasopharyngeal carcinoma
Oncology Sys. Review
Immune checkpoint blockade shows promise but faces resistance challenges in nasopharyngeal carcinoma Immune checkpoint blockade may help treat nasopharyngeal carcinoma
This narrative review examines immune checkpoint blockade in nasopharyngeal carcinoma. It highlights that while 5-year overall survival for …
A narrative review suggests immune checkpoint blockade could guide new treatments for nasopharyngeal carcinoma, though resistance remains a …
Gastric-type endocervical adenocarcinoma in Peutz-Jeghers syndrome: a case and literature review
Oncology Sys. Review
Gastric-type endocervical adenocarcinoma in Peutz-Jeghers syndrome: a case and literature review Rare cancer in woman with Peutz-Jeghers syndrome detailed
This case report and literature review describes a 44-year-old woman with Peutz-Jeghers syndrome and gastric-type endocervical adenocarcinom…
A rare cervical cancer in a woman with Peutz-Jeghers syndrome offers clues for early detection and treatment.
Meta-analysis of CDK4/6 inhibitor rechallenge shows improved progression-free survival in advanced breast cancer
Oncology Meta-analysis
Meta-analysis of CDK4/6 inhibitor rechallenge shows improved progression-free survival in advanced breast cancer Switching drugs offers hope for advanced breast cancer patients facing treatment failure
This meta-analysis synthesizes data from phase II and III clinical trials involving 1396 patients with hormone receptor-positive, HER2-negat…
A large review found that restarting a specific cancer drug after stopping it can delay disease growth by nearly two months compared to stan…