Gut-lung axis in lung cancer: soluble metabolites lead, neural pathways remain hypothetical
Gut Health Links May Influence Lung Cancer Treatment Paths
This narrative review with a systematic search examined 168 studies on the gut-lung axis in non-small-cell and small-cell lung cancer. Solub…
New research explores how the gut-lung axis and specific metabolites might play a role in managing lung cancer treatments.
Lipid metabolism reprogramming emerges as key mechanism of endocrine resistance in ER+ breast cancer
Fat metabolism changes help breast cancer cells resist treatment
This systematic review synthesizes evidence that lipid metabolism reprogramming, including fatty acid synthesis, cholesterol metabolism, lip…
New research identifies how changes in fat metabolism allow certain breast cancer cells to survive and resist standard hormone therapies.
Spatial immune-ecology framework proposed for gastric and GEJ adenocarcinoma ICI selection
Spatial Features Help Map Immune Responses in Stomach Cancer
This narrative guideline review proposes a spatial immune-ecology framework for advanced gastric and gastroesophageal junction adenocarcinom…
New research maps how the immune system interacts with stomach and esophageal cancer to help experts understand why some treatments work bet…
FDA-approved AI solutions for cancer histopathology are limited to a narrow range of applications
Only Four FDA Approved AI Solutions Exist for Cancer Histopathology
This guideline reviews the current state of AI in digital histopathology. It identifies only 4 FDA-approved solutions for a narrow range of …
While artificial intelligence is growing in cancer pathology, only four FDA-approved tools currently exist for specific clinical uses.
Divide-Survive Matrix decouples proliferation from survival architecture in tumor assessment
New tool helps doctors assess tumor aggression and behavior
This guideline introduces the Divide-Survive (DvS) Matrix, a visual interpretive structure for multidisciplinary teams to assess tumor aggre…
A new visual framework helps medical teams separate a tumor's growth speed from its ability to survive and persist in the body.
PPSS shows rapid metastatic progression despite neoadjuvant Adriamycin, Ifosfamide, and Mesna
Case Report Details Aggressive Synovial Sarcoma After Treatment
This case report describes a 60-year-old woman with primary pulmonary synovial sarcoma who received neoadjuvant Adriamycin, Ifosfamide, and …
A 60-year-old woman's synovial sarcoma shrank with chemo, but spread widely just four months after surgery.
Rezvilutamide plus ADT with efavirenz-based ART yields PSA decline in one HIV-positive mHSPC patient
Rezvilutamide Shows Promise for Prostate Cancer in HIV Patients
This is a single-patient case report describing rezvilutamide plus androgen deprivation therapy in an HIV-positive patient with high-volume …
A single patient with both HIV and advanced prostate cancer showed significant improvement after starting a specific combination of treatmen…
Splenic hilum nodal involvement is rare in pancreatic body adenocarcinoma with a 1.1% prevalence
Nodal Involvement Near the Spleen Linked to Pancreatic Cancer
This meta-analysis of 2260 patients evaluates the prevalence of splenic hilum and splenic artery nodal involvement in pancreatic ductal aden…
New data shows that while certain lymph nodes near the spleen are often involved in pancreatic cancer, they may not change survival outcomes…
Low inferior mesenteric artery ligation does not significantly impact survival in rectosigmoid cancer patients
Surgery Technique Comparison Shows Similar Outcomes for Rectosigmoid Cancer
This meta-analysis of 1152 patients with rectosigmoid cancer compared low versus high inferior mesenteric artery ligation. The analysis foun…
A review of surgical techniques for rectosigmoid cancer shows that two different artery ligation methods result in similar survival rates.
MRI-based radiomics models achieve 0.91 AUC for predicting GPC3 expression in hepatocellular carcinoma
MRI Radiomics Models Predict GPC3 Expression in Liver Cancer
This meta-analysis of 7 retrospective studies evaluated the diagnostic accuracy of MRI-based radiomics for predicting GPC3 expression in 1,2…
New MRI-based radiomics models show high accuracy in predicting GPC3 expression, offering a noninvasive way to identify patients for targete…
Hypoxia-inducible factor 1 alpha promotes aggressive phenotypes and treatment resistance in cervical cancer
HIF Factors Linked to Aggressive Cervical Cancer Growth
This narrative review explores the role of hypoxia-inducible factor (HIF) and HIF-1α in cervical cancer progression. The authors conclude th…
New research identifies how specific proteins called HIF and HIF-1α may drive tumor growth and treatment resistance in cervical cancer.
High Dietary Inflammatory Potential Correlates with Increased Risk of Oral Cancer
High Dietary Inflammation Linked to Increased Risk of Oral Cancer
A meta-analysis reveals that high dietary inflammatory potential significantly increases oral cancer risk, highlighting the role of nutritio…
A high inflammatory diet may increase the risk of oral cancer, suggesting that changing your eating habits could help protect your oral heal…