AI diagnostic tools show high accuracy but limited real-world validation in systematic review
Artificial intelligence shows high accuracy in detecting various medical conditions
This systematic review of 24 studies synthesizes evidence on AI and deep learning for disease detection across multiple imaging modalities. …
New analysis of 24 studies shows AI tools can reach over 90% accuracy in spotting everything from lung cancer to skin disorders.
Metabolic reprogramming of chondrocytes through impaired oxidative phosphorylation contributes to articular cartilage collapse
Cells' energy crisis may drive osteoarthritis cartilage collapse
This systematic review synthesizes literature regarding metabolic reprogramming in chondrocytes during osteoarthritis. The authors conclude …
Osteoarthritis may be fueled by a cellular energy crisis, not just wear and tear. A new review suggests targeting metabolism could lead to n…
FDA Approves Retevmo (selpercatinib) for RET-Driven Cancers
FDA approves new drug Retevmo for certain lung and thyroid cancers.
FDA approved Retevmo (selpercatinib) for adult and pediatric patients with RET fusion-positive NSCLC, RET-mutant MTC, RET fusion-positive th…
The FDA approved Retevmo (selpercatinib) for adults with a type of lung cancer that has a specific gene change, and for children and adults …
FDA Approves Retevmo (selpercatinib) for RET Fusion-Positive Solid Tumors
FDA approves Retevmo for more cancers with RET gene fusions
The FDA approved Retevmo (selpercatinib) for adult and pediatric patients 2 years and older with RET fusion-positive solid tumors that have …
The FDA approved Retevmo (selpercatinib) for adults and children ages 2 and older with advanced solid tumors that have a RET gene fusion and…
Olanzapine containing regimens consistently improve complete response across all phases of chemotherapy-induced nausea and vomiting
Olanzapine helps manage nausea and vomiting during chemotherapy treatment
This network meta-analysis of 10,455 adults receiving chemotherapy found that olanzapine-containing regimens consistently improved complete …
New data shows olanzapine can effectively control nausea and vomiting for patients undergoing chemotherapy, with lower doses showing similar…
PD-1 inhibitor plus chemotherapy improves progression-free survival and overall survival in driver gene-negative NSCLC
Adding PD-1 inhibitors to chemotherapy improves lung cancer survival
This network meta-analysis of 20 randomized controlled trials evaluated treatments for driver gene-negative non-small cell lung cancer with …
Combining a specific immunotherapy drug with chemotherapy may help patients with certain types of lung cancer and liver spread live longer.
Platelet-rich fibrin may reduce medication-related osteonecrosis of the jaw risk during tooth extractions
Platelet-rich fibrin may lower jaw bone damage risks
Researchers evaluated the impact of platelet-rich fibrin on patients undergoing tooth extractions while receiving antiresorptive or antiangi…
New data suggests using platelet-rich fibrin during tooth extractions could lower the risk of severe jawbone complications for patients on s…
Very late-onset Myasthenia Gravis is associated with higher AChR-antibody positivity and lower thymoma prevalence
Age of Onset Linked to Specific Myasthenia Gravis Markers
This meta-analysis examines the impact of age at onset on clinical and pathological profiles in patients with Myasthenia Gravis. The analysi…
New research shows that the age at which a person develops Myasthenia Gravis is linked to specific antibody types and tissue patterns.
PSMA-targeted radioligand therapies including 177Lu-PSMA-617 improve progression-free survival and overall survival in mCRPC
Radioligand Therapy Shows Promise for Advanced Prostate Cancer Patients
This narrative review examines the clinical role of PSMA-targeted radioligand therapies, specifically 177Lu-PSMA-617, 225Ac-PSMA, and 223Ra …
New radioligand therapies like 177Lu-PSMA-617 show improved survival rates for patients with advanced and metastatic prostate cancer.
TROP2-targeting ADCs achieve 50.6% ORR in EGFR-mutant NSCLC following tyrosine kinase inhibitor failure
Antibody-drug conjugates show promise for lung cancer after TKI failure
This systematic review and meta-analysis of 1092 patients found that antibody-drug conjugates (ADCs) provide significant clinical benefits f…
New research highlights how specific antibody-drug conjugates may offer better outcomes for patients with certain types of lung cancer.
Doxorubicin-loaded graphene nanoplatform chemo-photothermal therapy significantly suppresses tumor volume in breast cancer xenograft models
Combining graphene and light shows promise for breast cancer
This meta-analysis of preclinical studies evaluates doxorubicin-loaded graphene nanoplatform chemo-photothermal therapy (CPT) compared to ph…
A new method combining a graphene platform with heat therapy may shrink breast cancer tumors more effectively than using heat alone.
Parasite-derived molecules exert both pro-tumour and anti-tumour effects in experimental cancer models
Parasite Molecules Show Potential for Both Cancer Growth and Inhibition
This systematic review of 34 studies examines the mechanisms by which parasites and their products influence tumor growth. Findings indicate…
New research into parasite-derived products reveals they can either promote tumor growth or help fight cancer depending on the specific mole…