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Ophthalmology

168 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
C-reactive protein levels significantly higher in normal tension glaucoma patients
Ophthalmology Meta-analysis
C-reactive protein levels significantly higher in normal tension glaucoma patients Inflammation marker linked to one type of glaucoma
This meta-analysis of 766 patients found significantly higher CRP levels in normal tension glaucoma (NTG) compared to controls, but no signi…
People with normal tension glaucoma had higher CRP levels, a sign of inflammation, than those without glaucoma. The finding may help identif…
Slow-coagulation transscleral cyclophotocoagulation provides greater IOP reduction than micropulse transscleral cyclophotocoagulation in glaucoma
Ophthalmology Meta-analysis
Slow-coagulation transscleral cyclophotocoagulation provides greater IOP reduction than micropulse transscleral cyclophotocoagulation in glaucoma Slow-coagulation Treatment Shows More IOP Reduction for Glaucoma
This systematic review and meta-analysis of 992 patients compared three cyclophotocoagulation modalities for glaucoma. The analysis found th…
A new review suggests slow-coagulation treatment may lower eye pressure more effectively than micropulse methods for patients with glaucoma.
Fluocinolone Acetonide Implant Shows Reduced Injection Frequency for Diabetic Macular Edema
Ophthalmology RCT
Fluocinolone Acetonide Implant Shows Reduced Injection Frequency for Diabetic Macular Edema Fluocinolone Acetonide Implant May Reduce Injection Frequency for DME
A Phase 4 trial shows fluocinolone acetonide implants achieve similar visual outcomes to aflibercept with significantly fewer total injectio…
A new eye implant for diabetic macular edema may significantly reduce the number of monthly injections needed to maintain vision.
miR-29a-3p and miR-204-5p are downregulated in diabetic nephropathy as potential biomarker candidates
Ophthalmology Meta-analysis
miR-29a-3p and miR-204-5p are downregulated in diabetic nephropathy as potential biomarker candidates Specific MicroRNA Signatures Linked to Type 1 Diabetes Complications
This systematic review and meta-analysis of 9 studies involving 34 contrasts identified specific circulating miRNA signatures associated wit…
Researchers identified specific microRNA signals that may help track kidney and eye damage in patients with Type 1 Diabetes.
Melbourne Rapid Fields provide comparable diagnostic information to Humphrey Field Analyzer for glaucoma perimetry
Ophthalmology Meta-analysis
Melbourne Rapid Fields provide comparable diagnostic information to Humphrey Field Analyzer for glaucoma perimetry Melbourne Rapid Fields Provide Comparable Data to Humphrey Field Analyzer
This meta-analysis of 9 studies involving 777 eyes compares Melbourne Rapid Fields (MRF) and Humphrey Field Analyzer (HFA) performance. The …
A new analysis shows the Melbourne Rapid Fields test provides similar glaucoma data to standard tests while offering a faster testing time.
Germline BAP1 variants are associated with aggressive clinical phenotypes in patients with uveal melanoma
Ophthalmology Sys. Review
Germline BAP1 variants are associated with aggressive clinical phenotypes in patients with uveal melanoma Genetic variants linked to more aggressive eye cancer cases
This systematic review examines the clinical phenotype of uveal melanoma in patients harboring germline pathogenic or likely pathogenic BAP1…
A specific genetic marker, BAP1, is linked to earlier diagnoses and higher risks of spreading in certain types of eye cancer.
Age, smoking, and systemic factors are associated with increased risk of age-related macular degeneration
Ophthalmology Meta-analysis
Age, smoking, and systemic factors are associated with increased risk of age-related macular degeneration Risk Factors Linked to Age-Related Macular Degeneration
This umbrella review synthesizes epidemiological evidence regarding 53 distinct risk factors for age-related macular degeneration. The analy…
New research identifies how lifestyle factors like smoking, diet, and high blood pressure may link to age-related macular degeneration.
DHA and ARA supplementation significantly reduces risk of severe retinopathy of prematurity in preterm infants
Ophthalmology Meta-analysis
DHA and ARA supplementation significantly reduces risk of severe retinopathy of prematurity in preterm infants DHA and ARA Supplementation May Reduce Severe Retinopathy Risk
This meta-analysis of randomized trials evaluates enteral DHA and ARA supplementation for retinopathy of prematurity (ROP) in preterm infant…
Supplementing preterm infants with DHA and ARA may lower the risk of severe, sight-threatening eye conditions like retinopathy of prematurit…
Deep learning algorithms outperform ophthalmologists in detecting AMD and differentiating wet from dry cases
Ophthalmology Meta-analysis
Deep learning algorithms outperform ophthalmologists in detecting AMD and differentiating wet from dry cases Deep learning algorithms outperform doctors in detecting age-related macular degeneration
This systematic review and meta-analysis evaluates the diagnostic performance of deep learning (DL) algorithms for identifying age-related m…
New data shows deep learning tools can identify eye diseases with higher accuracy than senior specialists, offering a powerful new way to sc…
XEN-only surgery achieves lower postoperative IOP than trabeculectomy but has higher bleb needling rates
Ophthalmology Meta-analysis
XEN-only surgery achieves lower postoperative IOP than trabeculectomy but has higher bleb needling rates New analysis compares surgical options for open angle glaucoma
This systematic review and meta-analysis of 56 studies compared XEN-only, Phaco-XEN, and trabeculectomy for open-angle glaucoma. Findings in…
Two different surgery types for glaucoma both lower eye pressure, but one method may lead to fewer complications during follow-up care.
FDA Approves Fluorescite (fluorescein sodium) for Retinal and Iris Angiography
Ophthalmology FDA Approval
FDA Approves Fluorescite (fluorescein sodium) for Retinal and Iris Angiography FDA approves Fluorescite injection for eye imaging tests.
The FDA approved Fluorescite Injection 10% for diagnostic fluorescein angiography or angioscopy of the retina and iris vasculature. The adul…
The FDA approved Fluorescite Injection 10% for use in eye imaging tests to examine blood flow in the retina and iris. It helps doctors detec…
Combined phacoemulsification and angle filtering reduce intraocular pressure and medication needs in glaucoma patients
Ophthalmology Meta-analysis
Combined phacoemulsification and angle filtering reduce intraocular pressure and medication needs in glaucoma patients Combined surgery lowers eye pressure better than cataract surgery alone
This meta-analysis of 14 randomized controlled trials evaluated combined phacoemulsification and angle filtering compared to phacoemulsifica…
For glaucoma patients with cataracts, combining two procedures in one surgery may better protect vision than cataract surgery alone.