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Ophthalmology

168 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Aflibercept 8 mg extended dosing maintains visual gains with fewer injections versus 2 mg every 8 weeks in DME
Ophthalmology RCT
Aflibercept 8 mg extended dosing maintains visual gains with fewer injections versus 2 mg every 8 weeks in DME Aflibercept 8 mg every 16 weeks matches standard dosing for diabetic macular edema
This randomized, double-masked, noninferiority phase 2/3 trial enrolled 658 patients aged ≥ 18 years with center-involved diabetic macular e…
A new trial shows that aflibercept 8 mg every 16 weeks works as well as the standard 2 mg every 8 weeks for diabetic macular edema with fewe…
Systematic review and meta-analysis links pregnancy to higher risk of central serous chorioretinopathy
Ophthalmology Meta-analysis
Systematic review and meta-analysis links pregnancy to higher risk of central serous chorioretinopathy Pregnancy increases risk of central serous chorioretinopathy by more than five times
This systematic review and meta-analysis evaluates the association between pregnancy and central serous chorioretinopathy (CSC) using data f…
A large review found pregnancy raises the risk of central serous chorioretinopathy significantly. This matters for expectant mothers and doc…
Systematic review and meta-analysis of uveitis subtypes in European tertiary centers
Ophthalmology Meta-analysis
Systematic review and meta-analysis of uveitis subtypes in European tertiary centers European data show most adult uveitis cases are anterior or non-infectious
This systematic review and meta-analysis of 30 471 patients from European tertiary centers found that anterior uveitis is the most common su…
A large review of 30,471 patients found that over half of uveitis cases were anterior and nearly half were non-infectious across Europe.
Motivational Interviewing Workshop Improves Communication Skills in Ophthalmology Residents
Ophthalmology RCT
Motivational Interviewing Workshop Improves Communication Skills in Ophthalmology Residents Motivational Interviewing Workshop Boosts Glaucoma Counseling Skills
This pilot RCT with 20 ophthalmology residents found that a 1-hour Motivational Interviewing workshop improved standardized patient encounte…
A simple one-hour class helps doctors talk to glaucoma patients in ways that actually change behavior and improve medication use.
Brolucizumab Protocol for Chronic Central Serous Chorioretinopathy Compared to Multivitamins
Ophthalmology RCT
Brolucizumab Protocol for Chronic Central Serous Chorioretinopathy Compared to Multivitamins Doctors test new eye drug for stubborn fluid without neovascularization
This protocol describes a randomized controlled trial comparing intravitreal brolucizumab to oral multivitamins in 42 patients with chronic …
A new eye drug trial could help people with stubborn fluid in their retina by comparing it to vitamins in a strict study.
Systematic review finds radiotherapy combined with anti-VEGF therapy increases risk of vision loss compared to anti-VEGF monotherapy in nAMD
Ophthalmology Meta-analysis
Systematic review finds radiotherapy combined with anti-VEGF therapy increases risk of vision loss compared to anti-VEGF monotherapy in nAMD Radiotherapy plus anti-VEGF therapy increases vision loss risk for nAMD
This systematic review and meta-analysis evaluated radiotherapy combined with anti-VEGF therapy versus anti-VEGF monotherapy for neovascular…
Adding radiotherapy to anti-VEGF treatment for wet macular degeneration was linked to a higher risk of vision loss compared to anti-VEGF alo…
Systematic review and meta-analysis of intra-arterial chemotherapy for pediatric retinoblastoma outcomes
Ophthalmology Meta-analysis
Systematic review and meta-analysis of intra-arterial chemotherapy for pediatric retinoblastoma outcomes Meta-analysis links intra-arterial chemotherapy to better outcomes for pediatric retinoblastoma
This systematic review and meta-analysis evaluated intra-arterial chemotherapy (IAC) versus intravenous chemotherapy (IVC) for pediatric ret…
A meta-analysis of twelve studies suggests intra-arterial chemotherapy improves survival and eye salvage compared to intravenous chemotherap…
Meta-analysis compares intravitreal vs subretinal tPA for submacular hemorrhage
Ophthalmology Meta-analysis
Meta-analysis compares intravitreal vs subretinal tPA for submacular hemorrhage Two injection methods for eye bleeding show similar vision results over time
This meta-analysis of 353 eyes compared intravitreal and subretinal injection of tissue plasminogen activator for submacular hemorrhage.
A review of 353 eyes found that injecting medicine into the eye chamber or under the retina offered similar vision outcomes and safety profi…
Corneal biomechanics and endothelial morphology in healthy Saudi adults: a cross-sectional study
Ophthalmology Cohort
Corneal biomechanics and endothelial morphology in healthy Saudi adults: a cross-sectional study Thicker corneas in healthy adults drive lower pressure readings
This cross-sectional study of 122 healthy Saudi adults aged 18–40 years found that corneal biomechanics are primarily driven by central corn…
In a Saudi group of healthy adults, thicker corneas were the main factor lowering pressure readings, while eye shape played a smaller role.
Genetic testing completion rates and diagnostic yield vary by race in hereditary eye disorders patients
Ophthalmology Cohort
Genetic testing completion rates and diagnostic yield vary by race in hereditary eye disorders patients Genetic Testing Gaps Leave Many With Eye Disorders Undiagnosed
This retrospective cohort study evaluated 1466 patients with clinically diagnosed hereditary eye disorders at the Wilmer Eye Institute's Gen…
New data shows that race and age create unfair barriers to genetic testing for eye diseases, leaving many patients without answers.
Review: Eye Rubbing Techniques Raise Corneal Temperature in Healthy Young Adults
Ophthalmology
Review: Eye Rubbing Techniques Raise Corneal Temperature in Healthy Young Adults Rubbing your eye with a fingertip raises corneal temperature significantly
This cross-sectional experimental study in 93 healthy adults aged 19-29 found that fingertip, knuckle, and fingernail eye rubbing significan…
A study of 93 healthy young adults found that rubbing the eye with a fingertip, knuckle, or fingernail all raised corneal temperature signif…
Perioperative taVNS Reduces Pain and Insomnia After Glaucoma Surgery
Ophthalmology RCT
Perioperative taVNS Reduces Pain and Insomnia After Glaucoma Surgery Vagus nerve stimulation lowers pain after glaucoma surgery
This randomized trial of 94 patients undergoing glaucoma surgery found that perioperative transcutaneous auricular vagus nerve stimulation (…
A trial found that vagus nerve stimulation reduced pain and improved sleep for patients having glaucoma surgery under general anesthesia.