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Ophthalmology

102 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Subretinal saline injection added to vitrectomy for diabetic macular edema with hard exudates
Ophthalmology RCT
Subretinal saline injection added to vitrectomy for diabetic macular edema with hard exudates Does a simple salt solution injection help eyes with diabetic swelling?
A randomized trial in 56 patients with diabetic macular edema and hard exudates compared vitrectomy with subretinal balanced salt solution i…
A simple salt solution injection under the retina helped patients with diabetic eye swelling see better and reduced fluid buildup within sev…
Combined cataract and retrobulbar Ahmed drainage surgery shows preliminary IOP reduction in advanced glaucoma
Ophthalmology Cohort
Combined cataract and retrobulbar Ahmed drainage surgery shows preliminary IOP reduction in advanced glaucoma Small study explores combined eye surgery for advanced glaucoma in Black patients
A retrospective cohort of 12 Black and Afro-Latino patients with advanced glaucoma underwent combined phacoemulsification and retrobulbar/in…
A new combined eye surgery lowered pressure and reduced daily drops for advanced glaucoma patients, with stable vision and no serious compli…
Ex vivo VK-X3000 analysis reveals higher Descemet's membrane roughness in Fuchs endothelial corneal dystrophy compared to healthy controls
Ophthalmology
Ex vivo VK-X3000 analysis reveals higher Descemet's membrane roughness in Fuchs endothelial corneal dystrophy compared to healthy controls New Lens Reveals Hidden Patterns in Fuchs Eye Disease
This observational study analyzed ex vivo specimens from 38 FECD patients and 4 healthy donors using the VK-X3000 system.
A new 3D microscope maps tiny bumps on the eye's back layer to reveal hidden patterns in Fuchs eye disease progression.
Most near reading charts in community clinics deviate from ISO size standards
Ophthalmology
Most near reading charts in community clinics deviate from ISO size standards Study finds most near vision reading charts do not meet international size standards
A measurement study of 19 near reading charts from community optometry clinics found only 1 chart (5.26%) had all text sizes within ISO tole…
Most near vision reading charts used by eye doctors fail international size standards, meaning test results can vary depending on which char…
FDA Approves Eylea HD (aflibercept) for nAMD, DME, Diabetic Retinopathy, and Macular Edema Following RVO
Ophthalmology FDA Approval
FDA Approves Eylea HD (aflibercept) for nAMD, DME, Diabetic Retinopathy, and Macular Edema Following RVO FDA approves a new, higher-dose version of the eye medicine Eylea
The FDA has approved Eylea HD, a VEGF inhibitor, for the treatment of neovascular age-related macular degeneration, diabetic macular edema, …
FDA approves higher-dose Eylea to treat four eye conditions that damage the retina and threaten vision, potentially reducing how often patie…
Phacoemulsification with endoscopic cyclophotocoagulation lowers IOP and medication needs versus phaco alone in PACG with cataract
Ophthalmology RCT
Phacoemulsification with endoscopic cyclophotocoagulation lowers IOP and medication needs versus phaco alone in PACG with cataract Combined glaucoma and cataract surgery shows modest pressure benefit in small study
This randomized controlled trial enrolled 66 patients with primary angle closure glaucoma and cataract.
Adding a laser treatment to cataract surgery lowered eye pressure and reduced medication needs for patients with a specific type of glaucoma…
Meta-analysis finds contralateral IOP reduction after unilateral selective laser trabeculoplasty
Ophthalmology Meta-analysis
Meta-analysis finds contralateral IOP reduction after unilateral selective laser trabeculoplasty Unilateral SLT treatment linked to lower pressure in the other eye
A systematic review and meta-analysis of 9 studies (478 eyes) in POAG and OHT patients found unilateral SLT was associated with a mean contr…
Treating one eye with laser therapy lowers pressure in the other eye by an average of 1.85 mmHg without reported safety concerns.
Vitreoretinal surgery yields high reattachment rates in familial exudative vitreoretinopathy-associated retinal detachment
Ophthalmology Meta-analysis
Vitreoretinal surgery yields high reattachment rates in familial exudative vitreoretinopathy-associated retinal detachment Surgery outcomes for FEVR retinal detachment vary by procedure type and disease stage
This systematic review and meta-analysis evaluated 682 eyes from 19 observational studies of patients with familial exudative…
Surgery success for FEVR retinal detachment depends on disease stage, with scleral buckling achieving a 90 percent reattachment rate for sim…
PHOMS observed in both arteritic and nonarteritic anterior ischemic optic neuropathy in small cohort
Ophthalmology Cohort
PHOMS observed in both arteritic and nonarteritic anterior ischemic optic neuropathy in small cohort Small study finds PHOMS in both A-AION and NA-AION eyes with no clear difference
An exploratory retrospective cohort study of 22 patients with A-AION or NA-AION found PHOMS in both subtypes (36.4% vs 18.2%), with no stati…
A bright retinal spot called PHOMS appears in both types of optic nerve ischemia, suggesting it signals blood flow damage rather than the sp…
Optic nerve sheath fenestration in IIH associated with improved visual function and reduced papilledema
Ophthalmology Cohort
Optic nerve sheath fenestration in IIH associated with improved visual function and reduced papilledema Early OCT and vision changes after optic nerve surgery for idiopathic intracranial hypertension
A retrospective case series of 35 patients with idiopathic intracranial hypertension who underwent bilateral optic nerve sheath fenestration…
Optic nerve swelling and vision improved after surgery for idiopathic intracranial hypertension, though some nerve cell layers thinned over …
Arclight Project training repositioned Malawian eye-care workers and sustained device use over three years
Ophthalmology
Arclight Project training repositioned Malawian eye-care workers and sustained device use over three years Low-cost eye tools changed roles for health workers in Malawi
This qualitative follow-up study examined Ophthalmic Clinical Officers and Health Surveillance Assistants in central Malawi three years afte…
Low-cost eye tools in Malawi turned health workers into trusted community leaders, strengthening connections between clinics and villages ov…
Subretinal fibrosis develops in 40-50% of nAMD eyes after 5 years of anti-VEGF therapy, associated with worse vision
Ophthalmology Meta-analysis
Subretinal fibrosis develops in 40-50% of nAMD eyes after 5 years of anti-VEGF therapy, associated with worse vision How often does scarring develop in treated macular degeneration eyes?
A systematic review and meta-analysis of 58 studies in anti-VEGF-treated nAMD eyes found subretinal fibrosis developed in approximately 10-1…
Scarring in treated macular degeneration eyes affects 10% to 15% within two years and up to half by five years, causing vision loss averagin…