Observational study evaluates dynamic prediction model for clozapine initiation in Danish schizophrenia patients
Can we predict who needs clozapine soon? A new model says yes for many patients.
This observational research article evaluates a dynamic prediction model designed to forecast incident clozapine prescriptions within 365 da…
A new model predicts which schizophrenia patients need clozapine within a year, helping doctors start this life-saving treatment sooner for …
Elobixibat improved constipation in schizophrenia or depression patients during postmarketing surveillance in Japan.
New Hope for Constipation in Mental Health Patients
This postmarketing cohort study evaluated elobixibat in 105 patients with schizophrenia and 129 with depression in Japan. Defecation frequen…
A new drug helps millions with mental health conditions overcome severe constipation caused by their mood-stabilizing medications.
Parecoxib reduces postoperative anxiety but not cognitive decline in pancreaticoduodenectomy patients
Pain Drug Cuts Anxiety After Major Surgery
This randomized controlled trial of 80 patients undergoing laparoscopic pancreaticoduodenectomy evaluated intravenous parecoxib versus salin…
A common pain drug called parecoxib significantly lowers anxiety and may reduce mental fog for patients recovering from major pancreatic sur…
Polygenic risk scores show stronger associations with comorbid anxiety and depression cases in cohort studies
Do anxiety and depression share the same genetic roots when they appear together?
This observational cohort study in UK Biobank and MoBa participants found polygenic risk scores for anxiety and depression were more strongl…
When anxiety and depression occur together, their shared genetic risk is much stronger than when each disorder appears alone.
Digital self-hypnosis with essential oils for subsyndromal generalized anxiety in adults: study protocol
Anxiety Relief in Minutes—No Therapy Needed
This study protocol outlines a randomized controlled trial of 630 adults with subsyndromal generalized anxiety, comparing digital self-hypno…
A new digital tool combines guided self-hypnosis with essential oils to help adults with mild anxiety feel calmer without needing therapy or…
Cognitive Remediation Therapy Re-analysis Shows Benefit Over Treatment As Usual on Global Assessment Scale
When Patients Rank Treatment Success Differently Than Doctors
This re-analysis of a randomized controlled trial evaluated Cognitive Remediation Therapy versus treatment as usual among participants and s…
Patients and doctors value different treatment benefits, and letting patients help decide what counts as success can change how we understan…
Meta-analysis of VELscope diagnostic accuracy for oral potentially malignant disorders
Meta-analysis reviews VELscope device for detecting oral potentially malignant disorders
This meta-analysis of 24 studies evaluated VELscope for detecting oral potentially malignant disorders. Pooled sensitivity was 84% and speci…
The VELscope screening tool catches most oral cancer cases but often flags healthy mouths as risky, causing unnecessary worry and extra test…
Multimodal MRI Protocol to Study Interoception in Schizophrenia
How Schizophrenia Changes the Body’s Inner Signals
This is a protocol for a cross-sectional multimodal MRI study in 30 individuals with schizophrenia and 30 matched healthy controls. It outli…
Understanding how the brain reads the body could unlock new ways to treat the emotional struggles of schizophrenia.
Systematic review finds simulation-based training equivalent or superior to traditional methods in veterinary education.
New Tools Train Vets to Keep Your Pets Safer
This systematic review synthesizes evidence on physical models and simulation-based training versus traditional teaching in veterinary educa…
New training tools let vet students practice on realistic models, so your pet gets safer surgeries and better care from doctors who are full…
Systematic review and meta-analysis on depression and anxiety prevalence in liver cirrhosis
More Than Half of Cirrhosis Patients Face Anxiety, New Global Study Reveals
This meta-analysis synthesized data from 23 studies including 979,113 patients with liver cirrhosis to estimate the prevalence of depression…
This massive global review proves that mental health struggles are a hidden, widespread crisis for people living with liver disease.
Narrative review on social participation decline in young and middle-aged stroke survivors
Young Stroke Survivors Struggle to Rejoin Life
This narrative review synthesizes evidence on social participation in young and middle-aged stroke survivors. It reports that participation …
Young stroke survivors in China face a harsh reality: up to 80% lose independence and struggle to return to work or family life years after …
Baseline cognitive scores predict antidepressant non-response in Chinese adults with MDD
Depression’s Hidden Symptom Predicts Treatment Success
This retrospective observational cohort study of 321 Chinese adults with major depressive disorder found that higher baseline PDQ-D-20 score…
Worse thinking problems before treatment predict poorer antidepressant results, helping doctors spot patients who need different care.