Methylphenidate ER Improves Functional Capacity in Stable Schizophrenia
Methylphenidate extended-release improved daily function in stable schizophrenia patients
This randomized open-label trial in 24 stable adults with schizophrenia found that 4 weeks of methylphenidate ER improved functional capacit…
A new trial found that methylphenidate extended-release helped adults with schizophrenia spectrum disorder improve daily function and reduce…
Preoperative Pain Education Reduces Postoperative Pain and Postpartum Depression After Cesarean
Pre-op pain education cuts pain and depression after C-section
This randomized trial of 160 women scheduled for elective cesarean section found that adding preoperative pain education to routine guidance…
Talking about pain before surgery helps new moms feel less pain and less depression after a C-section.
Text-message CBT treatment reduced generalized anxiety disorder symptoms in young adults compared to wait-list control
Text Message Therapy Reduces Anxiety Symptoms in Young Adults
This randomized clinical trial enrolled 103 young adults with generalized anxiety disorder or major depressive disorder.
A text message treatment for depression also significantly lowered anxiety symptoms in young adults compared to waiting for care.
Cariprazine showed modest weight reduction versus aripiprazole in schizophrenia patients previously treated with olanzapine
Cariprazine shows modest weight benefit over aripiprazole in schizophrenia patients
This trial compared cariprazine to aripiprazole in patients with schizophrenia who had previously used olanzapine.
A trial found cariprazine linked to slightly more weight loss than aripiprazole in people with schizophrenia, though overall differences wer…
Self-help mindfulness and CBT interventions reduce depression and anxiety in distressed students
Mindfulness Apps Help Students Reduce Depression and Anxiety Symptoms
This RCT in 335 distressed university students in China found that self-help mindfulness interventions, with or without CBT, significantly r…
A trial found that online mindfulness programs significantly reduced depression and anxiety symptoms in stressed university students compare…
Protocol for Systematic Review and Meta-Analysis of Dopaminergic Measures in Opioid Use Disorder
Opioid addiction changes brain chemistry in lasting ways
This publication outlines a protocol for a systematic review and meta-analysis investigating dopaminergic measures in adults with opioid use…
People with opioid addiction have clear changes in brain chemistry that may explain why cravings persist, even after stopping use, and could…
Scoping review of Montmorency tart cherry consumption on muscle soreness and recovery
Tart cherries may help your muscles recover after hard workouts
This scoping review analyzed 28 clinical trials regarding the effects of Montmorenly tart cherry consumption on healthy adults.
Tart cherries may help your muscles recover strength after exercise, but results vary across studies.
Meta-analysis finds NLRP3 inflammasome components upregulated in animal depression models
New research links brain inflammation to depression symptoms in animals
This systematic review and meta-analysis of 170 animals (85 depression model, 85 controls) found that protein and mRNA levels of NLRP3, ASC,…
Scientists found that specific inflammation markers rise in the brains of animals with depression, pointing to a new target for future treat…
Meta-analysis identifies moderators of the bidirectional anxiety-alcohol relationship
Age and peer influence link anxiety and alcohol use
This meta-analysis of 55 longitudinal studies examined mediators and moderators in the anxiety-alcohol pathway.
Age, peer drinking, and family experiences shape how anxiety and alcohol use are linked, a review of 55 studies finds.
Digital mental health intervention reduces anxiety and depression in Chinese high school students
A 12-week digital program reduced depression and anxiety in Chinese high school students
This 12-week randomized controlled trial in 390 Chinese high school students found that a digital mental health literacy intervention integr…
A 12-week digital program reduced depression and anxiety in Chinese high school students compared to controls, offering a scalable solution …
Meta-analysis reviews psychosis prevalence in bipolar disorder patients across 285 studies
Psychosis common in bipolar disorder, review finds
This meta-analysis reviews data from 285 studies regarding the prevalence of psychosis and psychotic symptoms in patients with bipolar disor…
Nearly half of people with bipolar disorder experience psychosis, and 8% also have schizophrenia, a review of 285 studies finds.
Systematic review finds aerobic exercise improves executive function in adults with major depressive disorder
Aerobic exercise improves thinking skills in adults with major depression
This systematic review and three-level meta-analysis evaluated aerobic exercise in adults with major depressive disorder.
Adults with major depression who exercised regularly showed better focus and mental flexibility. This review found clear benefits for core t…