Unipolar mania prevalence in patients with bipolar type I disorder is 21.1%
About one in five people with bipolar disorder experience mania
This meta-analysis of 35 independent samples indicates a pooled prevalence of unipolar mania (UM) in adults with bipolar type I disorder of …
New data shows that over 20% of adults with bipolar type I disorder experience unipolar mania, highlighting a need for better clinical aware…
Ketamine may improve abstinence in substance use disorder, but evidence is limited
Ketamine May Help People With Substance Use Disorder Stay Abstinent
This meta-analysis of 798 participants suggests ketamine may improve abstinence rates in substance use disorder. However, the abstract lacks…
A new analysis suggests ketamine could improve abstinence rates for people with substance use disorder.
Habitual Mindfulness Practice reduces depressive and anxiety symptoms in adults with mild to moderate distress
Mobile mindfulness practice helps reduce anxiety and depression symptoms
This randomized controlled trial of 686 adults found that Habitual Mindfulness Practice (HMP) significantly reduced depressive and anxiety s…
A new mobile app approach to mindfulness shows promise for adults struggling with mild to moderate anxiety or depression.
Virtual reality stress paradigms elicit consistent autonomic responses but variable endocrine and neural activations
Virtual reality tools can trigger and measure human stress responses
This scoping review of 21 studies maps virtual reality (VR) stress paradigms across subjective, autonomic, endocrine, neural, and behavioral…
New research maps how different virtual reality scenarios trigger physical and mental stress, helping scientists study how our bodies react …
Exercise-induced lactate via the lactate-HCAR1 axis serves as a potential immunometabolic mechanism in depression
Exercise Lactate May Offer New Path for Treating Depression
This narrative review explores the lactate-HCAR1 axis as a link between exercise metabolism and inflammatory responses in depression. The au…
New research explores how the lactate produced during exercise might help regulate inflammation and brain responses in people with depressio…
Theoretical models and frameworks clarify stakeholder perspectives during the commercial digital health innovation life cycle
New framework helps teams navigate complex digital health technology
This systematic review synthesizes 12 theories, models, and frameworks to map the landscape of healthcare digitalization. The findings categ…
A review of 12 key models shows how different teams can better manage and design tools for digital healthcare.
Structured exercise reduces depressive symptoms and improves quality of life in adults with rheumatoid arthritis
Structured Exercise May Reduce Depression in Rheumatoid Arthritis Patients
This meta-analysis of 11 trials involving 1652 participants indicates that structured exercise significantly reduces depressive symptoms (He…
Structured exercise programs may help reduce feelings of depression and anxiety while improving quality of life for adults with rheumatoid a…
Elevated peripheral blood Neuron-specific enolase levels correlate with increased risk of MDD and PSD
Blood Protein Levels Linked to Risk of Major Depression
This meta-analysis of 18 studies indicates that abnormally elevated levels of peripheral blood Neuron-specific enolase (NSE) are closely rel…
New research identifies a specific protein in the blood that may serve as an early warning sign for major and poststroke depression.
Family-centered care and parent-infant interaction improve well-being of NICU parents
Specific Support Programs Improve Well-being for Parents in the NICU
A scoping review of 87 articles found that family-centered care, parent-infant interaction enhancement, and infant care education improve pa…
Parents of infants in neonatal intensive care units can find improved well-being through family-centered care and education on infant develo…
Psychosis symptoms in youth linked to 2-fold higher risk of later mental health disorders
Psychosis symptoms in youth linked to later mental health disorders
This meta-analysis of studies in children and youth under 25 without baseline mental health diagnoses found that psychosis spectrum symptoms…
Children and teens with mild psychosis symptoms face double the risk of later mental health disorders, a new analysis finds.
Active VNS increases likelihood of meaningful improvement in suicidal ideation with OR 1.43
Active vagus nerve stimulation may reduce suicidal thoughts in depression
This randomized controlled trial of 463 participants with treatment-resistant depression and baseline suicidal ideation found that active VN…
A new trial shows that active vagus nerve stimulation can help reduce suicidal thoughts for people with treatment-resistant depression.
Ecological momentary interventions reduce depressive symptoms with moderate effect in meta-analysis
Ecological Momentary Interventions Help Reduce Symptoms of Depression
This meta-analysis of 1258 individuals found that ecological momentary interventions (EMIs) significantly reduced depressive symptoms (Hedge…
A review of studies shows that real-time digital interventions can significantly reduce depression symptoms and improve quality of life.