Hospitalized AE-RA-ILD patients receiving JAK inhibitors alongside glucocorticoids showed mixed respiratory outcomes over three months
A Rheumatoid Arthritis Drug May Help Save Lungs in Crisis
This retrospective observational case series examined six consecutive patients hospitalized for acute exacerbation of rheumatoid arthritis–a…
A small study suggests a familiar arthritis pill may help calm sudden, dangerous lung flare-ups in people with rheumatoid arthritis.
In children with first psychotic symptoms, 23.5% had substance- or medically-associated psychosis after extensive workup
Medical testing found substance or medical causes in 23.5% of youth with new psychosis
This retrospective cohort study evaluated 68 children and adolescents admitted for a first presentation of psychotic symptoms at a tertiary …
Medical testing found substance or medical causes in 23.5% of youth with new psychosis, proving a thorough workup is essential before diagno…
Racial discrimination linked to negative symptoms in schizophrenia via defeatist beliefs
Why Some Patients Can't Shake the "I'll Fail" Mindset
An observational study of 208 Black and White individuals with schizophrenia-spectrum disorder found that Black participants had greater neg…
For Black Americans with schizophrenia, the stress of racism may fuel low motivation and withdrawal that standard medication rarely touches.
Observational cohort study links early-life adversity to smaller caudate volumes in children with enduring pain
Adversity Changes the Brain, But Not Pain Yet
This observational cohort study from the Adolescent Brain Cognitive Development (ABCD) Study examined multimodal MRI markers in children ass…
Early-life hardship changes the brain, but new research shows it does not cause lasting pain in children.
Children with ASD reported lower perceived navigation ability than typically developing peers in an observational study
Autistic Kids Navigate Fine, But Feel Lost Inside
This observational study compared 26 children with high-functioning autism spectrum disorder (ASD) to 25 typically developing peers.
Autistic kids navigate just as well as peers, yet they often feel lost inside, revealing a gap between ability and confidence.
Deep brain stimulation of the anterior limb of the internal capsule reduced OCD symptoms in a small observational study
A Tiny Brain Signal May Show When OCD Treatment Is Working
This observational study evaluated deep brain stimulation (DBS) of the anterior limb of the internal capsule in 10 clinically responsive…
A drop in a specific brain wave signal may tell doctors when deep brain stimulation is finally easing severe obsessive-compulsive disorder s…
Meta-analysis shows psychotherapy effect sizes vary by baseline depression severity compared to control conditions
Depression Treatment Works Best For The Most Severe Cases
This meta-analysis evaluated 47,315 patients with depression to assess how baseline severity influences treatment response.
Depression therapy works best for the most severe cases, with response rates improving as symptoms worsen, according to a large review of 38…
Omega-3 supplementation reduces stress, anxiety, and depression in Saudi adults over three months
Omega-3s Help Calm Stress And Improve Sleep
A randomized, double-blind, placebo-controlled trial in 64 Saudi adults found that omega-3 supplementation (500 mg EPA + 250 mg DHA) signifi…
A new trial shows omega-3 supplements significantly reduce stress, anxiety, and depression while improving sleep and memory in people with s…
Ten-week Baduanjin exercise improved sleep and mood in college students with Qi-deficiency constitution
Could a gentle 10-week exercise routine help college students feel less anxious and sleep better?
This small randomized study enrolled 37 college students with Qi-deficiency constitution and sleep problems, assigning 18 to control and 19 …
Many college students struggle with sleep and anxiety, often feeling a sense of low energy or weakness.
Systematic review finds exercise prescription linked to mood, cognition, and stress resilience benefits
Your Workout May Boost Mood Through Your Gut, Not Just Your Brain
A systematic review suggests exercise prescription is associated with advantageous impacts on mood, cognitive function, and stress resilienc…
Daily exercise may lift your mood by changing gut bacteria to produce mood-boosting molecules that signal your brain.
Internet-based CBT relapse predictors in remitted major depressive disorder patients
For those who beat depression with online therapy, what risks relapse and how to stay well?
This secondary analysis of a randomized controlled trial examined relapse in 83 remitted patients with major depressive disorder over 12 mon…
After beating depression with online therapy, about one-third of people relapse within a year, but finishing the program and seeking care wh…
Zanubrutinib-combined therapy in heavily treated non-GCB DLBCL: retrospective two-center cohort of 27 patients
New hope for tough lymphoma cases
A retrospective two-center cohort of 27 heavily treated patients with relapsed/refractory non-GCB DLBCL evaluated zanubrutinib-combined ther…
Combining zanubrutinib with other treatments helped 74% of patients with tough, hard-to-treat lymphoma respond after standard options failed…