Narrative review examines pathophysiological mechanisms of post-exertional malaise in PCC and CFS
Why Your Body Crashes After Small Efforts
This narrative review synthesizes current understanding of post-exertional malaise (PEM) in individuals with Post COVID-19 Condition and Chr…
Even a short walk can trigger a dangerous crash in people with Long COVID and Chronic Fatigue Syndrome because their cells stop making energ…
Phase 2b trial finds basmisanil does not improve cognitive deficits in schizophrenia
Schizophrenia Drug Failed to Fix Thinking Skills
A Phase 2b multicenter RCT randomized 213 patients with cognitive impairment associated with schizophrenia to basmisanil (80 mg or 240 mg tw…
A schizophrenia drug that improved thinking skills in animals failed to help human patients improve their cognitive function in a clinical t…
Cannabis use associated with emotion regulation difficulties in adolescents and young adults
Cannabis May Quietly Reshape How Young People Handle Emotions
A systematic review and meta-analysis of 3,801 adolescents and young adults aged 12–30 years found cannabis use was associated with greater …
Regular cannabis use in teens and young adults may weaken brain skills needed to manage strong feelings and control impulses.
PRISM implementation support increased depression care pathway adoption in obstetric practices compared to standard care
Pregnant Women Are Missing Depression Care — This Program Changes That
This cluster randomized controlled trial evaluated PRISM, which combines MCPAP for Moms with practice-level implementation support, against …
A new support program doubled the rate at which pregnant women with depression were identified and followed up in obstetric practices.
Mandala coloring three times weekly for 12 weeks reduces anger and death anxiety in nursing home elders
Coloring Calm: How Art Helps Elderly Residents Fight Anger and Fear
A randomized controlled study of 80 nursing home older adults (40 experimental, 40 control) tested art-based mandala coloring three times we…
A simple 12-week art program can significantly reduce feelings of rage and fear of dying in older adults living in care facilities.
Systematic review synthesizes HCP perceptions on digital mental health tools augmenting care
Digital Tools Help, But Can't Replace Doctors
This systematic review and thematic synthesis of healthcare professional perceptions found that digital mental health tools are endorsed to …
Digital mental health tools can boost access to care, but doctors insist they must support face-to-face visits rather than replace them.
Meta-analysis finds large symptom reductions with Detached Mindfulness for OCD and panic disorder
Could a new mindfulness approach help reduce symptoms of OCD and panic disorder?
This systematic review and meta-analysis synthesized evidence on Detached Mindfulness as a stand-alone intervention for obsessive–compulsive…
A new mindfulness approach called Detached Mindfulness helped reduce symptoms of OCD and panic disorder while also lowering feelings of sadn…
Scoping review identifies service delivery as main health equity action for refugees and minorities in One Health
Why Fair Health Care Still Leaves Many Behind
A scoping review of 62 reviews found that service delivery actions were the predominant approach to health equity for refugees, immigrants, …
A major new review shows that health fairness efforts rarely connect with programs protecting people, animals, and the planet together — eve…
Traditional South African medicinal plants may improve reproductive performance in goats
Ancient Plants May Hold the Key to Healthier Goats
This narrative review examined the use of traditional South African medicinal plants, including Securidaca longepedunculata and Moringa olei…
South African farmers may boost goat fertility and fight infections naturally using ancient healing plants found right outside their door.
Cohort study shows schizophrenia patients and siblings differ in gray matter volume compared to healthy controls
Why Age Changes Brain Risk
This cohort study examined gray matter volume patterns in 31 schizophrenia patients, 62 healthy siblings, and 31 healthy controls.
Age changes brain risk for schizophrenia siblings, as new findings show brain structure differs between those in their teens and those in th…
Meta-analysis finds gamma neuromodulation benefits in schizophrenia and major depressive disorder
Gamma neuromodulation showed symptom improvements in schizophrenia and depression in this review
This systematic review and meta-analysis synthesizes evidence on gamma neuromodulation for neuropsychiatric disorders.
Gamma neuromodulation improved positive and negative symptoms, anxiety, and thinking skills in schizophrenia while reducing depression in ma…
Pathway-partitioned schizophrenia polygenic risk scores associate with age of psychosis onset in multi-ancestry cohorts
Why Schizophrenia Hits Some People Younger Than Others
This cohort study utilized harmonized North American and UK Biobank datasets to evaluate genome-wide and pathway-partitioned schizophrenia p…
Tiny blood vessel and brain wiring genes may shape when schizophrenia first appears, helping families understand why some young adults devel…