Chronic Insomnia in Hospitalized Adults: Associated Conditions and Metabolic Abnormalities
Elderly women with insomnia often have heart disease, infections, and metabolic issues
This retrospective observational study evaluated 871 hospitalized adults aged 18 to 100 years with chronic insomnia at a single center in Ch…
Hospitalized older women with insomnia frequently face infections, heart disease, and blood sugar problems, a single-center study finds.
ECG abnormalities observed in 45.5% of pediatric patients on antipsychotics in a real-world cohort
Most kids on antipsychotics show normal heart tests
This observational cohort study of 430 children and adolescents found that 45.5% exhibited at least one ECG abnormality during antipsychotic…
Nearly half of children on antipsychotics had minor heart test changes, but dangerous rhythms were absent, suggesting monitoring may be targ…
Observational cohort links symptom severity subgroups to poorer functioning and brain volume in psychosis and depression risk
Severe Mental Symptoms Share Hidden Common Cause
This observational cohort study stratified 749 participants into transdiagnostic symptom severity subgroups.
This could explain why different mental illnesses feel so similar in early stages.
Blood biomarker variance in UK Biobank influenced by technical, demographic, and behavioral factors
Why Blood Tests Fail to Predict Mental Health
This UK Biobank cohort study examined how technical, demographic, behavioral, and temporal factors influence 29 blood biomarkers.
Many doctors rely on blood work to check your physical health.
SCC DBS with at-home LFP data collection predicts stable recovery in treatment-resistant depression
New brain signal predicts stable recovery for depression patients at home
This cohort study evaluated ten SCC DBS participants with treatment-resistant depression.
A specific brain signal helps predict stable recovery in depression patients using at-home data, showing promise for better care.
WGS in multiplex OCD pedigrees identifies rare variants in NPY5R, DLGAP1, and MAPK8IP3
OCD Genes Found in Family Clusters
This case report performed whole genome sequencing in 25 individuals from two multiplex OCD pedigrees to identify rare protein-disrupting va…
Imagine a family where multiple members — parents, children, siblings — all struggle with obsessive thoughts and compulsive rituals.
Review of P-NQLS psychometric validation in U.S. parents of children aged 6-18 years
Parents See Kids’ Mental Health Differently Than Doctors Do
This narrative review summarizes a psychometric validation study of the Parent-report Nationwide Quality of Life Scale (P-NQLS) in 2,251 U.S…
Six-year-old Maya used to laugh at everything.
Retrospective case-case study links interpersonal trauma exposure to younger suicide deaths and distinct genetic profiles
People with trauma histories die by suicide at younger ages
This retrospective case-case study analyzed 8,738 suicide deaths to compare individuals with and without interpersonal trauma exposure.
A study of over 8,700 suicide deaths found those with interpersonal trauma histories died younger and had different genetic and clinical pro…
Preclinical and EEG analysis links autism neurosubtypes to opposing electrophysiological profiles
Brain Signals Reveal Two Opposite Types of Autism, New Study Shows
This is a preclinical modeling and human EEG analysis publication.
This research shows autism isn't one condition but two opposite brain types, which could lead to more personalized treatments in the future.
Cross-sectional evaluation finds supervisory system improves suicide risk detection in LLMs
AI Chatbots Often Miss Suicide Risk. A New Safety Layer Could Change That
A cross-sectional evaluation of 224 paired suicide-related clinical vignettes compared an independent supervisory safety architecture with a…
Adding a separate safety monitor to AI chatbots could prevent them from missing signs of suicide risk, making digital mental health tools sa…
Systematic review shows small, significant executive function gains in youth mindfulness interventions
Mindfulness training shows small improvements in executive function for youth aged 3 to 18 years
This systematic review and meta-analysis evaluated Mindfulness-based interventions (MBIs) excluding yoga-only programs in typically developi…
Mindfulness training in schools gives children and teens small but consistent boosts to focus, memory, and flexible thinking skills.
Culturally adapted CBT reduced anger in war-exposed Syrian and Palestinian adolescents in Jordan
New Group Therapy Cuts Anger in War-Traumatized Teens
This single-arm pretest–posttest study evaluated a culturally adapted cognitive behavioral group intervention in 50 Syrian and Palestinian a…
A new group therapy helps war-traumatized teens in Jordan stop feeling trapped by rage and rebuild connections with friends and family.