Meta-analysis associates deep sedation with increased delirium and mortality in ICU patients
Deep Sedation in ICU Linked to Higher Delirium and Death Risk
This meta-analysis of 3,466 patients examines the relationship between deep sedation and clinical outcomes in the ICU. The findings suggest …
A new analysis of over 3,400 ICU patients finds that deep sedation is linked to higher rates of delirium, death, and longer hospital stays, …
Expert consensus guidelines for N-acetylcysteine use in various respiratory conditions
Experts share new guidance on using N-acetylcysteine for lung health
This expert consensus guideline reviews the clinical utility of N-acetylcysteine (NAC) across several respiratory diseases. The authors sugg…
Medical experts have reached a consensus on how a specific supplement might help people managing various chronic lung diseases.
Treat-to-target strategy improves gout remission vs symptom-driven care
A new gout treatment strategy is changing outcomes
This open-label RCT in 308 adults with gout and hyperuricaemia found that a treat-to-target strategy (urate-guided titration) led to higher …
Many people with gout stay in pain despite treatment, but aiming for a specific uric acid level nearly doubles the chance of remission.
Psychosis Prevalence in SLE Patients: Meta-Analysis of 31,495 Adults
Lupus psychosis risk is higher than doctors thought
A meta-analysis of 31,495 SLE patients found psychosis prevalence of 4.5% overall and 20.5% in NPSLE, highlighting the need for clinical vig…
Many people with lupus may face a higher risk of psychosis than previously believed, and a key antibody could help spot those most at risk.
Systematic review explores the role of RNA methylation in autoimmune rheumatic diseases
RNA Methylation Could Change How We Treat Joint Pain
This systematic review examines the impact of RNA methylation on various autoimmune rheumatic diseases, including rheumatoid arthritis and s…
A new review explains how tiny chemical tags on RNA control inflammation and could lead to better treatments for painful autoimmune diseases…
Late-onset rheumatoid arthritis shows higher DAS28 scores and lower remission rates compared to young-onset disease in a meta-analysis
Meta-analysis compares treatment outcomes in older versus younger rheumatoid arthritis patients
This meta-analysis reviewed data from over 5000 patients with late-onset rheumatoid arthritis (LORA) and young-onset rheumatoid arthritis (Y…
A large review found older patients with rheumatoid arthritis had higher disease activity and lower remission rates on biologics compared to…
Vitamin D supplementation may reduce disease activity in SLE: a systematic review and meta-analysis
Vitamin D supplements may calm lupus activity, study finds
This systematic review and meta-analysis of 847 patients with systemic lupus erythematosus found that vitamin D supplementation significantl…
A new analysis of 847 lupus patients suggests vitamin D supplements may reduce disease activity and improve immune markers.
Scoping review finds SGLT2 inhibitors show kidney protection in IgA nephropathy
Two major trials show kidney-protective effects for a specific IgA nephropathy group
This scoping review synthesizes evidence on SGLT2 inhibitors in IgA nephropathy.
Two large trials found kidney-protective effects for some IgA nephropathy patients taking SGLT2 inhibitors, while real-world data showed red…
Network meta-analysis finds exercise therapies reduce depressive symptoms in post-stroke depression
Exercise therapies reduce depression and improve function after stroke
This systematic review and network meta-analysis of 2,339 patients found that various exercise therapies significantly reduce depressive sym…
A network meta-analysis of nearly 2,400 patients found exercise therapies significantly reduce depressive symptoms and improve daily living …
Team-based care with rheumatological specialist assistants improved patient satisfaction in seropositive rheumatoid arthritis flares
Team-based care boosts satisfaction for rheumatoid arthritis patients
This randomized controlled trial enrolled 224 patients with seropositive rheumatoid arthritis during flares across a multicenter setting.
Rheumatoid arthritis patients were more satisfied with care from a team led by specialist assistants than with standard rheumatologist visit…
Individualized intervention plans improved stress management and pain management in African American lupus patients compared to usual care
Individualized plans may help African American lupus patients manage stress and pain
This randomized controlled trial evaluated individualized intervention plans versus a standardized chronic disease self-management program o…
A trial suggests personalized self-management options improved stress management and pain handling for African American lupus patients compa…
Narrative review discusses MicroRNAs in melanoma without reported outcomes or safety data
A review explores how MicroRNAs might relate to Melanoma
This narrative review examines the role of MicroRNAs in melanoma.
This narrative review discusses MicroRNAs in the context of Melanoma, offering a broad overview of current scientific understanding.