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N/A Completed N=175 Randomized Single-blind Health Services Research

A Collaborative Care Program to Improve Depression Treatment in Cardiac Patients

Source: ClinicalTrials.gov NCT00847132 ↗
Enrolled (actual)
175
Serious AEs
0.0%
Results posted
Mar 2017
Primary outcomePrimary: Rates of Adequate Depression Treatment at Discharge — 71.9; 9.5 percentage of participants

Summary

Depression in cardiac patients is common, persistent, and deadly. However, the vast majority of cardiac patients with depression go unrecognized and untreated, despite the existence of treatments that clearly improve depressive symptoms and may favorably impact survival. Our research group and others have found that depression recognition and treatment appears particularly limited among patients with acute cardiac illness, though this population may be the most vulnerable to the deleterious effects of depression. We propose a project, building on successful collaborative care depression management programs in outpatient settings, to address this important issue. The specific hypotheses behind the proposed research are that a collaborative care depression management program can be successfully adapted to inpatient cardiac units, and that such a program will lead to greater rates of adequate depression treatment and improvements in secondary outcomes. The following specific aims capture the stepwise goals of this program: 1. To determine whether a collaborative care depression management program ('Enhanced Care') leads to significantly increased rates of adequate depression treatment compared to usual care (screening and feedback) (Primary Aim). 2. To assess whether this Enhanced Care program has a lasting impact on adequate depression treatment, depressive symptoms, health-related quality of life, and adherence to medical recommendations at 6 weeks, 12 weeks, and 6 months, compared to usual care.

Outcome Measures

OutcomeResultp-value
PRIMARY
Rates of Adequate Depression Treatment at Discharge
71.9; 9.5
SECONDARY
Change in Depression Symptoms From Baseline to 6 Months
-8.98; -5.95; -8.73; -5.30; -8.67; -6.90

Eligibility Criteria

Inclusion Criteria

  • Inpatient admission for cardiac diagnosis
  • Positive depression evaluation (PHQ-2>2, PHQ-9>9)
  • Ability to provide informed consent

Exclusion Criteria

  • Active suicidal ideation
  • Bipolar disorder, psychotic disorder, active substance use disorder
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00847132). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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