N/A
N=22
Effects of Strengthening Exercise on the Brain for Early Dementia and Normative Older Adults
Cognitive Decline · Dementia · Alzheimer's Disease · Mild Cognitive Impairment
Bottom Line
View on ClinicalTrials.gov: NCT01264614 ↗Enrolled (actual)
22
Serious AEs
0.0%
Results posted
Mar 2015
Primary outcome: Primary: Stroop Test Performance From Pre- to Post-intervention — 137.67; 56.17; 116.51; 55.13 Time to complete (seconds)
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Strengthening exercise (Behavioral)
- Age
- Adult, Older Adult · 55+ yrs
- Sex
- All
- Sponsor
- Union College, New York
- Primary completion
- Apr 2011
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Stroop Test Performance From Pre- to Post-intervention |
137.67; 56.17; 116.51; 55.13 | — |
| PRIMARY Digits Backwards Test Performance From Pre- to Post-intervention |
4.10; 5.50; 3.90; 6.83 | — |
| PRIMARY Color Trails Test Performance From Pre- to Post-intervention |
250.00; 124.00; 259.01; 96.11 | — |
| PRIMARY Fuld Test Performance From Pre- to Post-intervention |
10.60; 18.80; 10.60; 18.60; 2.90; 6.60 | — |
| PRIMARY Figure Copy & Delayed Test Performance From Pre- to Post-intervention |
16.44; 28.67; 22.06; 30.33; 3.28; 14.50 | — |
| PRIMARY Neurophysiological Function Pre- & Post- Intervention |
— | — |
Summary
This study will evaluate the effects of low-intensity strengthening exercise on the brain (thinking and processing speed) for patients with early dementia, compared with normative older adults. Participants will engage in 3 months of exercise 3-5 times per week using a chair and small weights. It is hypothesized that there will be a significant improvement in brain function.
Eligibility Criteria
Inclusion Criteria
- Adult Day Program Participants with early dementia able to consent or assent with surrogate permission
- Control participants (55-100+ yo) able to participate at location with doctor permission
Exclusion Criteria
- history of significant TBI, psychiatric condition, substance abuse, physical conditions that preclude participation in cognitive testing or strengthening exercises
Data sourced from ClinicalTrials.gov (NCT01264614). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.