4,901 trials
Colitis, Ulcerative · Crohn Disease
Primary: Cmax: Maximum Observed Serum Concentration for Vedolizumab — 136.4120 microgram per milliliter (mcg/mL)
HIV Infections
Primary: Area Under the Concentration-time Curve From Time Zero (Pre-dose) Extrapolated to Infinite Time (AUC[0-infinity]) of GSK3640254 Following Single Oral Dose in Healthy…
Breast Cancer
Primary: Percent Correct on the Knowledge Measure (Objective Knowledge Score) — 84.6; 59.7 percentage of answers correct
Anaemia
Primary: Part 1: Area Under the Concentration-time Curve From Time Zero (Pre-dose) Extrapolated to Infinite Time (AUC [0-infinity]) of GSK1278863 and Its Metabolites — 296.2407…
Healthy Volunteers
Primary: Number of Participants With Clinically Significant Effects — 3; 1; 3; 2 Participants
Pulmonary Disease, Chronic Obstructive
Primary: Area Under the Concentration-time Curve From Time 0 to Infinity (AUC [0-inf]) of Danirixin for Part 1 — 6166.7; 6052.9; 5816.4; 5996.1 Hours*nanograms per milliliter
Tumors
Primary: AUC(0-24): Area Under the Concentration-time Curve From Time Zero to 24 Hours Postdose for Midazolam and 1'-Hydroxymidazolam — 92.5; 89.7; 117; 38.5 hour*nanograms per…
Malaria
Primary: Cmax: Peak Plasma Concentration — 277; 373.4444 ng/mL
Healthy, Young Adults
Primary: Balance Score — 9.9; 11.5; 7.0; 11.3 seconds — p=0.172
Allogeneic Hematopoietic Stem Cell Transplantation
Primary: Number of Participants With Dose-Limiting Toxicities (DLTs) — 0; 0 Participants
Cocaine Dependence
Primary: Cocaine Negative Urines — 10; 35; 14 percentage of cocaine-negative urines
Healthy Volunteers
Primary: Change-from-baseline Mean Effect of P03277 on QT Interval Expressed as QTc According to Fridericia's Formula (∆QTcF) — 0.97; 5.05; 0.24; -0.11 milliseconds
Leukemia · Lymphoma
Primary: Number of Patients Who Received 2 Doses of Natural Killer (NK) Cell Infusions — 3; 2; 5 Participants
Latent Tuberculosis · Latent Tuberculosis Bacteriology and Histology Unknown
Primary: Number of Participants With at Least One Adverse Event (AE) Through Day 210 — 8; 8; 9; 6 Participants
Recurrent Melanoma · Stage IV Melanoma · Tumors Metastatic to Brain
Primary: Maximum Tolerated Dose (MTD) of Ipilimumab — 3; 10 mg/kg