Phase 2 N=75 Study of Modified FOLFIRINOX in Advanced Pancreatic Cancer
Metastatic Pancreatic Cancer · Pancreatic Cancer
Primary: Progression Free Survival — 54; 97 percentage of participants
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Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=11 Cabozantinib (XL184) in Patients With Relapsed or Refractory Myeloma
Relapsed or Refractory Multiple Myeloma
Primary: Maximally Tolerated Dose — 40 mg
Phase 2 N=48 Dose-Ranging Study of Intranasal Kovacaine Mist in Pediatric Subjects
Anesthesia
Primary: Number of Participants Who Completed the Study Dental Procedure Without Need for Rescue by Injection of Local Anesthetic. — 6; 7; 8; 5 Participants
N/A N=24 Effects of Daytime Eszopiclone Administration in Shift Workers
Shift-Work Sleep Disorder
Primary: Nighttime Wakefulness Assessed by Mean Sleep Latency Across 4 Maintenance of Wakefulness Tests — 11.0; 14.75 minutes
Phase 2 N=87 Teprotumumab (RV 001) Treatment in Patients With Active Thyroid Eye Disease
Thyroid Associated Ophthalmopathies · Thyroid-Associated Ophthalmopathy
Primary: Responder Status at Week 24 — 9; 29; 36; 13 Participants — p=< 0.001
Phase 3 N=90 Comparison of Intranasal Kovacaine Mist, and Placebo for Anesthetizing Maxillary Teeth in Pediatric Patients
Anesthesia
Primary: Number of Participants Who Completed the Study Dental Procedure Without Need for Rescue by Injection of Local Anesthetic. — 46; 16 Participants
Phase 4 N=68 Does the Addition of Epinephrine Prolong the Duration of Spinal Anesthesia for Repeat Cesarean Section?
Spinal Anesthesia · Cesarean Section
Primary: Sensory Recovery — 135; 165; 120 minutes
Phase 3 N=110 Comparison of Intranasal Kovacaine Mist, Tetracaine Alone, and Placebo for Anesthetizing Maxillary Teeth in Adults
Anesthesia
Primary: Number of Participants Who Completed the Study Dental Procedure After Without Need for Rescue by Injection of Local Anesthetic. — 84.1; 27.3; 27.3 percentage of patients
N/A N=126 Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya Disease and Stroke Patients
Cerebrovascular Accident · Moyamoya Disease
Primary: Percentage of Regions With Collateral Versus Antegrade Blood Flow (Sensitivity) Correctly Identified Using MRI With Xenon Contrast Agent (Specificity) — 81.7; 88.9…
N/A N=11 Memantine for Neuroprotection and Cognitive Enhancement Following Traumatic Brain Injury
Traumatic Brain Injury
Primary: California Verbal Learning Test - Second Edition (CVLT-II) - Long Delay Free Recall — -2.000; -1.375 z-score
Phase 2 N=34 Brentuximab Vedotin Plus AVD in Limited-stage Hodgkin Lymphoma
Hodgkin Lymphoma
Primary: Complete Response Rate — 31 Participants
Phase 4 N=106 Does Duloxetine Reduce Sub-Acute Pain After Knee Arthroplasty?
Total Knee Arthroplasty
Primary: NRS Pain With Ambulation at 2 Weeks — 3.5; 3.8 NRS pain score
N/A N=34 Comparative Effectiveness of Decision Aids for Stable Chest Discomfort
Coronary Artery Disease · Stable Angina
Primary: Total Knowledge Score — 2.83; 4.0 knowledge score
N/A N=92 Utilizing Advance Care Planning Videos to Empower Perioperative Cancer Patients and Families
Cancer
Primary: Measured ACP Content in the Presurgical Consent Visit — 6; 5; 10; 8 Recordings
Phase 4 N=43 Stopping TDF Treatment After Long Term Virologic Suppression in HBeAg-negative CHB
Chronic Hepatitis B
Primary: Proportion of Participants With HBsAg Loss at Week 144 in Both Study Arms — 0.236; 0 Proportion of participants — p=0.022