N/A N=86 Performance of Dailies Total1® Contact Lenses for Astigmatism in Symptomatic Habitual Reusable Toric Lens Wearers
Astigmatism
Primary: Contact Lens Dry Eye Questionnaire (CLDEQ-8) Score — 16.8; 12.4 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=221 Efficacy and Safety of FIRTECH in Patients With Mild to Moderate Acute Low Back Pain
Low Back Pain
Primary: Percentage of Numerical Rating Scale (NRS) Responders at Day 5 — 72.5; 49.4 percentage of participants — p=0.002
N/A N=20 Development and Validation of a Tumour Oxygenation Monitoring Probe
Cancer
Primary: Count of MRIs Successfully Modelled for Oxygen Correlation — 10; 10 MRIs analyses
Phase 1 N=48 CPI-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Granulocytic Sarcoma
Granulocytic Sarcoma · Recurrent Adult Acute Myeloid Leukemia
Primary: Feasibility of Administering CPI-613 in Combination With High Dose Cytarabine and Mitoxantrone During Induction, Consolidation and Maintenance Therapies, Defined as…
Phase 4 N=20 Buspirone Treatment of Anxiety in Williams Syndrome
Williams Syndrome · Anxiety
Primary: Mean 16-Week Change in Pediatric Anxiety Rating Scale 5-Item Total Score — -7.9 score on a scale — p=<0.001
N/A N=133 Noninvasive Peripheral Nerve Stimulation for Medication-Refractory Primary RLS (The RESTFUL Study)
Restless Legs Syndrome
Primary: Number of Subjects for Which the Clinician Reported "Much Improved" or "Very Much Improved" on the Clinical Global Impressions-Improvement (CGI-I) Scale for TOMAC…
N/A N=420 Effect of Wearable Health Technology on Patients Treated for Chronic Pain at Geisinger Health System
Chronic Pain
Primary: Numerical Pain Score (NPS) — 5.48; 6.50; 6.48; 5.22 score on a scale
N/A N=257 Improving Outcomes for Care Partners of Persons With Traumatic Brain Injury
Caregivers
Primary: Change From Baseline in Self-reported Caregiver Strain as Measured by Traumatic Brain Injury Caregiver Quality of Life (TBI-CareQOL) Caregiver Strain — -1.09; 0.34 T Score
Phase 4 N=34 Safety, Tolerability and PK of TPOXX in Adults Weighing More Than 120 KG
Smallpox
Primary: AUC0-t — 29500 ng*h/mL
Phase 3 N=263 To Compare Brolucizumab to Aflibercept in Chinese Patients With Visual Impairment Due to Diabetic Macular Edema
Diabetic Macular Edema
Primary: Change From Baseline at Week 52 in Best-corrected Visual Acuity (BCVA) for the Study Eye. — 10.6; 11.9 Scores on a scale — p=0.013
N/A N=20 Intra-articular Injection in Arthroscopic Management of Temporomandibular Diseases
Temporomandibular Joint Disorders
Primary: Maximum Interincisal Opening (MIO) Measurements — 23.1; 27.9; 33.8; 35.6 Millimeter
N/A N=34,960 Study of Progression to Progressive Fibrosing Interstitial Lung Disease (PF-ILD) Incidence/Management and Treatment
Lung Diseases, Interstitial
Primary: Incidence Probability of Progression to Pulmonary Fibrosing-Interstitial Lung Disease (PF-ILDs) — 0.147; 0.249; 0.334; 0.395 Cumulative incidence probability
Phase 3 N=568 Study to Assess Efficacy and Safety of Cx601, Adult Allogeneic Expanded Adipose-derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula(s) in Participants With Crohn's Disease (CD)
Crohn's Disease
Primary: Percentage of Participants With Combined Remission at Week 24 — 46.32; 48.76 percentage of participants — p==0.571
N/A N=153 Cervical Cancer Self-Collection for Southeast Asian Immigrant and Refugee Women
Cervical Cancer Screening
Primary: Number of Participants Who Obtain or Self-Report Future Desire for Cervical Cancer Screening — 59; 71 Participants
Phase 3 N=30 Effect of Probiotic Supplementation on the Immune System in Patients With Ulcerative Colitis in Amman, Jordan
Ulcerative Colitis
Primary: The Level of Immunoglobulin (Ig) A — 270.42; 208.63 mg/dL