30 closest matches · ranked by relevance
Abdominal Abscess · Pelvic Abscess
Primary: Percentage of Patients Requiring Surgical Debridement for a Persistent Abscess Within 30 Days Following Initial Drainage — 3; 7 participants
Abscess
Primary: Number of Participants With Abscess Resolution — 11; 9 Participants
Abscess · Cellulitis
Primary: Number of Participants Who Experienced a 30% or Greater Reduction in Surface Area of Abscess — 6; 19 Participants — p=.0003
Complicated Appendicitis · Acute Appendicitis
Primary: Feasibility of the Use of Antibiotic Solution Instillation Following Intraoperative Diagnosis of Complex Appendicitis as Assessed by Percentage of Eligible Participants…
Skin Diseases, Infectious
Primary: Skin Abscess Resolution — 4; 3 participants
Abscess
Primary: Clinical Improvement at 7 Days After Incision and Drainage — 10; 14 participants
Perforated Appendicitis
Primary: Abscess After Appendectomy — 10; 10 number of patients
Abscesses
Primary: Treatment Failures at 7 Days — 15; 27 participants
Appendicitis · Perforated Appendicitis · Ruptured Appendicitis
Primary: Overall Cost of Care
Open Abdomen
Primary: Primary Closure Rate — 75; 67 % of participants
Acute, Perforated Appendicitis
Primary: Number of Participants With Postoperative Intra-abdominal Abscess — 6; 8 Participants
Abscess · Methicillin-Resistant Staphylococcus Aureus Infection
Primary: Recurrence Rates of Abscesses — 4; 14 participants
Suppurative Appendicitis
Primary: Post Operative Length of Stay — 8.2; 23.4 Hours
Infection
Primary: Number of Subjects Achieving Clinical Cure at Test of Cure (TOC) Visit in the Per Protocol Population — 315; 324; 37; 23 participants
Skin Disease, Bacterial · Abscess
Primary: Treatment Failures — 9; 4 participants — p=0.25
Gastrointestinal Injury · Complicated Diverticulitis
Primary: Rate of Surgical Site Infection — 5 Participants
Pain, Postoperative
Primary: Total Morphine Milliequivalent (MME) Use Postoperatively After Cesarean Delivery — 52; 68 Morphine milligram equivalents
Abscess
Primary: Sensitivity and Specificity of Bedside Emergency Ultrasound When Added to the Clinical Examination Compared With Clinical Examination Alone. — 94.7; 93.1; 84.2; 81.4…
Complicated Intra-Abdominal Infection
Primary: Duration of Hospitalization — 14.1 Days
Complicated Intra-abdominal Infections
Primary: Clinical Response of Eravacycline and Ertapenem Treatment Arms at the Test-of-cure (TOC) Visit in the Microbiological Intent-to-treat (Micro-ITT) Population — 191; 198…
Furunculosis
Primary: Number of Side-effects — 4; 2 Participants
SURGICAL SITE INFECTION
Primary: Surgical Site Infection — 6; 3 participants — p=<0.05
Intra-abdominal Infection
Primary: Clinical Response at the Test-of-Cure (TOC) Assessment Within the Clinically Evaluable (CE) Population — 89.9; 96.6; 10.1; 3.4 percentage of participants — p=0.0008
Complicated Intra-abdominal Infections
Primary: Number of Participants With Clinical Response at the Test of Cure (TOC) Visit — 62; 71 participants
Peritonsillar Abscess
Primary: Number of Participants With Recurrence of Peritonsillar Abscess — 10; 10 Participants — p=0.05
Abdominal Wall Defects
Primary: Confirmed Hernia Recurrence — 20 participants
Complicated Intra-abdominal Infection
Primary: Clinical Response to TP-434 and Ertapenem in the Microbiologically Evaluable (ME) Population at the Test-of-Cure Visit — 39; 41; 24; 3 participants
Complicated Intra-Abdominal Infection
Primary: Clinical Response at the Test of Cure (TOC) Visit in the Microbiologically Modified Intent-To-Treat (mMITT) Analysis Set (Primary Outcome for FDA). — 337; 349; 37; 30…
Pain Management
Primary: Postoperative Pain Examination — 3; 5; 2; 3 score on a scale
Complicated Intra-abdominal Infections · Complicated Appendicitis
Primary: Number of Participants With a Favorable Clinical Response at the Test-of-Cure (TOC) Visit in the Microbiological Intent-to-treat (Micro-ITT) Population — 177; 187; 7; 7…