N/A N=123 Technology-Based Prevention for Adolescents in Primary Care
Substance Use
Primary: Enrollment and Recruitment Rate — 61; 62 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 1 N=497 Middle School to High School Transition Project: Depression and Substance Abuse Prevention
Depression · Substance-Related Disorders
Primary: Change in Short Moods and Feelings Questionnaire (SMFQ) — 2.19; 1.21 units on a scale — p=<0.05
N/A N=88 Adolescent Interventions to Manage Self-regulation of T1D (AIMS T1D)
Self-regulation · Medication Adherence
Primary: Change From Baseline in Youth Executive Function (Behavioral EF) at 8 Weeks (Z-score) — 0.02; -0.02 z-score
N/A N=66 Congenital Heart Adolescents: Program of Transition Evaluation Research
Congenital Heart Defects
Primary: Transition Readiness Assessment Questionnaire (TRAQ) Score — 2.77; 2.95; 3.80; 3.92 units on a scale
N/A N=15 Adolescent Attention to Emotion Study
Depression
Primary: Affect-biased Attention Following Neurofeedback (Immediately Post-Intervention) — .41 Proportion (0-1) — p=.004
N/A N=146 Prevention of Adolescent Risky Behaviors: Neural Markers of Intervention Effects
Risk-Taking · Adolescent Behavior
Primary: Changes in Emotional Regulation — 54.43; 52.02; 54.47; 60.77 T Score — p=0.003
N/A N=168 A Study Examining Adolescents With Non-Suicidal Self-Injury
Self-Injurious Behavior · Deliberate Self-Harm
Primary: Self-Injurious Thoughts and Behaviors Interview (SITBI) - Lifetime Episodes — 73.29; 0 episode count
N/A N=226 Reducing HIV Risk Among Adolescents: Evaluating HEART for Teens
HIV Infections · Sexually Transmitted Diseases
Primary: Acceptability — 88; 83 Participants
N/A N=122 Adolescents With Substance Use Disorders Transitioníng From Residential Treatment to the Community
Substance Use · Adolescent Behavior
Primary: Change in Proportion of Days Used Outside of Controlled Environment — .27; .35; .35; .32 proportion of days used — p=.12
N/A N=353 Testing a Digital Intervention for Adolescents
Rumination · Stress, Psychological
Primary: Change in Perceived Stress [Perceived Stress Scale (PSS)] — 26.33; 25.26; 22.01; 24.67 score on a scale — p=<.001
N/A N=120 Developing Text-based Support for Parents of Adolescents After an Emergency Department Visit
Suicide
Primary: Percentage of Eligible Youth-Parent Dyads Who Agree to Participate in the Study, — 125 Parent-youth dyads
N/A N=32 Activating and Connecting Teens (ACT) Study
Depression
Primary: Depression — 9.63 score on a scale
N/A N=16 African American Knowledge Optimized for Mindfully Healthy Adolescents
Depression
Primary: Attendance at First Depression Treatment Appointment — 5; 6 participants
Phase 2 N=3,901 A Stage-Based Expert System for Teen Dating Violence Prevention
Violence · Bullying
Primary: Number of Participants Perpetrating Physical Dating Violence During Follow-up — 240; 307 participants — p=<.0001
N/A N=48 Group Depression Treatment for Autistic Youth
Autism Spectrum Disorder · Depression · Suicidal Ideation
Primary: Change in Severity of Adolescent Depressive Symptoms, Self-report — 8.14 T-score
N/A N=15 The S.M.A.R.T. Project: Stress Management and Resilience Training for Teens
Depression Mild · Resilience, Psychological · Adolescent Behavior
Primary: Time to Incident Depression — 36; 18.86 weeks — p=0.02
N/A N=23 Insulin Resistance in Adolescents
Insulin Resistance
Primary: Linear Relationship Between HOMA-IR and Cognitive Function (R-squared) — 0.205; 0.299; 0.738; 0.0264 R-squared — p=0.162
N/A N=460 Alcohol, Marijuana, and Risky Sex: Group Interventions With Detained Adolescents
Risk Reduction Behavior · Health Behavior · Sexual Behavior
Primary: Number of Participants With Risky Sexual Behavior Measured for 1 Year — 143; 155; 162 Participants
N/A N=302 I-ACT With Check Yourself
Adolescent Behavior
Primary: Number of Health Risk Behaviors — 2.23; 2.62 score on a scale
N/A N=222 Reducing HIV Risk Among Adolescents: Evaluating Project HEART
HIV · Sexually Transmitted Diseases
Primary: 6-item Self-report of Program Acceptability — 84; 94; 101; 60 Participants
N/A N=153 Treatment for Adolescent Marijuana Abuse
Marijuana Abuse
Primary: Marijuana Abstinence (2 Weeks or Greater) — 72.5; 68.6; 45.1 percentage of participants
N/A N=59 Behavioral Treatment of Adolescent Substance Use
Substance Use Disorders
Primary: Any Cannabis Abstinence — 13; 18 participants
N/A N=80 Examining Reward-Related Predictors and Mechanisms of Change in BA Treatment for Anhedonic Adolescents
Anhedonia
Primary: Change in Anhedonic (Snaith-Hamilton Pleasure Scale; SHAPS) Symptoms — 7.06; -1.29 units on SHAPS scale
N/A N=109 Improving Diabetes in Emerging Adulthood
Diabetes Mellitus, Type 1
Primary: Hemoglobin A1c — 9.6; 9.8; 8.5; 10.9 Percentage (%) of glycated hemoglobin — p=.219
N/A N=96 Effects of a Single-session Implicit Theories of Personality Intervention on Early Adolescent Psychopathology
Anxiety Symptoms · Depressive Symptoms
Primary: Change in Children's Depression Inventory (CDI) From Baseline to 9-month Follow-up — 12.35; 11.76; 11.54; 11.66 scores on a scale
N/A N=36 Improving Adherence in Adolescents and Young Adults With Bipolar Disorder
Bipolar Disorder
Primary: Change From Baseline in the Tablet Routine Questionaire (TRQ) "Past Month" Item at 24 Weeks — 21.5; 28.0 percent of medications not taken
N/A N=140 Young Parents Program, Project Connect
Adolescents · 18 and Under When Child Was Born for Mothers · 25 and Under When Child Was Born for Fathers
Primary: Rapid Repeat Pregnancy — 8; 16 Participants — p=.037
N/A N=223 Self-guided Treatment for Adolescents Navigating Depression
Depressive Symptoms · Depression · Depressive Disorder
Primary: Depressive Symptom Severity at Post-intervention — 8.39; 11.03 units on a scale — p=<0.001
N/A N=202 Affective Social Buffering
Social Stress · Adolescent Behavior
Primary: Cortisol AUCi — -93.6397; -68.0959; -106.9105 (ug/dL)*minutes
N/A N=78 iTransition Development
Human Immunodeficiency Virus · HIV Seropositivity
Primary: Linkage to Adult Care — 16; 22; 0; 0 Participants