Phase 4 N=43 Chloroprocaine Spinal Anesthesia for Cervical Cerclage (CP Spinal)
Adverse Reaction to Spinal Anesthetic · Maternal Care for Cervical Incompetence
Primary: Time to Resolution of Motor Block — 109; 112 minutes
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=159 3 Local Anesthetics for Spinal Anesthesia in Primary Total Hip Arthroplasty
Osteoarthritis, Hip
Primary: Percentage Ambulating Early After Spinal Anesthesia — 9; 20; 35 Participants
Phase 4 N=82 Spinal Anesthesia Induced Hypotension During Cesarean Section
Hypotension
Primary: Incidence of Maternal Hypotension — 10.8; 27 percentage of participants
N/A N=23 Changes in Tissue and Cerebral Oxygenation Following Spinal Anesthesia in Neonates, Infants, and Children
Infants Undergoing Surgery
Primary: Cerebral Non-invasive Near Infrared Spectroscopy (NIRS) — 0.05 percentage change per minute
Phase 3 N=40 Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine 2% for Cesarean Section Under Spinal Anesthesia
Pregnant Women · Pain · Hypotension
Primary: Time to Regression of Motor Block — 180; 130 minutes
Phase 4 N=68 Does the Addition of Epinephrine Prolong the Duration of Spinal Anesthesia for Repeat Cesarean Section?
Spinal Anesthesia · Cesarean Section
Primary: Sensory Recovery — 135; 165; 120 minutes
N/A N=429 Predict Fluid Responsiveness in Spinal Anesthesia
Hypotension and Shock · Excessive Amount of Blood / Fluid Infusion
Primary: Percentage of Participants With Systemic Hypotensions — 68; 46; 65 Participants
N/A N=110 Phenylephrine in Spinal Anesthesia in Preeclamptic Patients
Preeclampsia · Hypotension
Primary: The Umbilical Artery pH — 7.22; 7.20 pH — p=.38
Phase 4 N=183 Spinal Anesthesia With Hyperbaric Levobupivacaine 0.75% for Ambulatory Knee Arthroscopy
Disorder of Knee · Anesthesia
Primary: Probability of Motor Block — 5; 20; 27 percentage of motor block
Phase 2 N=66 The Prevention of Hypotension After Epidural Analgesia After Major Surgery
Hypotension · Pain
Primary: Changes Between the 3 Groups Assessed by Blood Pressure Measurement — 5; 2; 3; 10 Participants — p=0.165
N/A N=196 Effect of Intra-abdominal Pressure to the Level of the Sensory Block at Caesarean Section Under Spinal Anesthesia
Obstetric Anesthesia Problems · High-Risk Pregnancy
Primary: The Level of Intra-abdominal Pressure (IAP) — 15.33 mm Hg
N/A N=116 Perioperative Intravenous Lidocaine or Epidural Anesthesia on Outcomes in Complex Spine Surgery
Spine Surgery
Primary: Mean Pain Scores — 4.4; 5.3 verbal response scores — p=<0.001
Phase 3 N=35 Minimal Effective Dose of Hyperbaric Spinal Bupivacaine for Saddle Block
Perianal Surgery
Primary: Minimal Effective Dose of Hyperbaric Bupivacaine — 1.9 milligrams
N/A N=260 Comparison of Two Spinal Needles Regarding Postdural Puncture Headache
Anesthesia; Adverse Effect, Spinal and Epidural, Headache · Complications; Anesthesia, Spinal and Epidural, in Pregnancy
Primary: Postdural Puncture Headache in Patients Receiving Spinal Anesthesia for Cesarean Section — 14; 10 participants
Phase 2 N=40 Estimation of the ED95 of Intrathecal Hyperbaric Prilocaine 2% With Sufentanyl for Scheduled Cesarean Delivery
Pregnant Women
Primary: Success of Anesthesia — 4; 4; 4; 1 Participants
Early Phase 1 N=70 Comparison of Chloroprocaine vs Lidocaine for Epidural Anesthesia in Cesarean Delivery
Surgical Anesthesia, Cesarean Section
Primary: The Onset Time to Surgical Anesthesia — 558; 655 seconds — p=0.10
Phase 4 N=36 Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery.
Nerve Block · General Anesthesia · Spinal Anesthesia
Primary: Time Until Patient is Ready for Discharge From Post-Anesthesia Care Unit (PACU) to Home. — 81; 43.5 Minutes
Phase 3 N=2,108 Regional Anesthesia and Breast Cancer Recurrence
Breast Neoplasms
Primary: Number of Participants Who Had Breast Cancer Recurrence After Breast Cancer Surgery — 111; 102 participants — p=0.84
N/A N=446 Thoraco Lumbar Vertebral Length and Bupivacaine Dosage in C-Section
Obstetric Anesthesia Problems · Bupivacaine Adverse Reaction
Primary: Hypotension Rate Among the Groups — 9; 26; 37 Participants
Phase 4 N=180 Effects of General Anesthesia and Spinal-Morphine Anesthesia on Recovery and Comfort After Benign Abdominal Hysterectomy
Hysterectomy (MeSH nr: E04.950.300.399)
Primary: Duration of Hospital Stay. — 46; 50 Hours
Phase 4 N=602 Prophylactic Ephedrine and Combined Spinal Epidurals for Labor
Labor Pain
Primary: Early Profound Fetal Bradycardia — 8; 14 participants — p=0.18
N/A N=170 Optimizing Dose of Bupivacaine in Combined Spinal Epidurals To Reduce Side Effects
Pregnancy
Primary: Maternal Blood Pressure — 78.2; 79.58; 80.52 mm/Hg
N/A N=394 Observational Study on 2-chloroprocaine Hydrochloride 1%
Neurological Complication, in Particular TNS or CES
Primary: Number of Participants With Adverse Events — 9; 5 participants
Phase 3 N=192 Wound Infusion vs Spinal Morphine for Post-caesarean Analgesia
Post Caesarean Analgesia
Primary: Duration of Effective Analgesia — 351; 380; 247 minutes
Early Phase 1 N=229 Comparison of 0.1 and 0.05mg Intrathecal Morphine for Post-cesarean Analgesia.
Cesarean Section
Primary: Time to First Narcotic Rescue Dose in the First 24 Hours Post-cesarean Delivery. — NA; 23.5 hours
N/A N=60 Epidural Anesthesia for Transurethral Resection of The Prostate
Epidural Catheter · Epidural Analgesia · Geriatric Cardiology
Primary: Time to Reach Sensory Block at T10 — 15.25; 10.50; 11.25 Minutes — p=0.05
Phase 2 N=110 1% Chloroprocaine(PF) vs. Bupivacaine Spinals
Return of Motor and Sensory Blockade · Anesthesia, Spinal · Decrease Discharge Time Status Post Hemorrhoidectomy
Primary: Recovery Time — 134.1; 161.9 minutes
N/A N=50 Accuracy of Manual Palpation vs Ultrasound for Spinal Anesthesia
Anesthesia, Local · Infant Conditions
Primary: Intended Interspace — 1; 24; 25 Participants
Phase 4 N=44 2 Dose Neuraxial Morphine for Prevention of PDPH
Postdural Puncture Headache
Primary: Number of Participants With Postdural Puncture Headache — 3; 4; 8; 10 Participants
Phase 4 N=81 Phenylephrine vs. Norepinephrine Infusion After Spinal Anesthesia for Cesarean Delivery
Effects of; Anesthesia, in Labor and Delivery
Primary: Number of Rescue Boluses to Maintain SBP — 25; 21 rescue boluses — p=0.12