30 closest matches · ranked by relevance
Psychomotor Retardation · Psychomotor Slowing · Schizophrenia and Related Disorders
Primary: Number of Responders at Week 3 — 4; 9; 0; 3 responders
Agitation Associated With Bipolar Disorder · Agitation,Psychomotor · Bipolar Disorder
Primary: Change From Baseline in the Positive and Negative Syndrome Scale- Excited Component (PEC) Total Score — 18.0; 18.0; 17.9; -10.4 score on a scale — p=<0.0001
Alzheimer's Disease · Psychosis · Agitation
Primary: Change in Neuropsychiatric Inventory (NPI) Agitation/Aggression Domain Score — 3.2; 2.5 score on a scale — p=0.53
Agitation · Schizophrenia · Schizo Affective Disorder
Primary: Change From Baseline in the Positive and Negative Syndrome Scale- Excited Component (PEC) Total Score — 17.5; 17.6; 17.6; -8.4 score on a scale — p=<0.0001
Alzheimer Disease · Psychomotor Agitation
Primary: Mean Clinical Global Impression of Change (CGIC) at Last Observation — 2.6; 4.5 units on a scale
Alzheimer's Disease · Disruptive Behavior
Primary: ADCS-Clinical Global Impression of Change in Agitation (ADCS-CGIC-A) — 3.434; 3.442 score on a scale — p=0.9904
Agitation
Primary: Change in the PANSS-EC Score Among Participants From Baseline to 2 Hours After Administration of the Medication. — -11.0; -11.5 score on a scale — p=>0.05
Alzheimer's Disease
Primary: Symptoms of Agitation as Measured by the Pittsburgh Agitation Scale — 7.14; 5.55; 5.69; 4.97 score on a scale — p=.015
Agitation in Patients With Dementia of the Alzheimer's Type · Alzheimer Disease · Agitation,Psychomotor
Primary: Change in CMAI Total Score — -15.4; -10.0; -11.5 score on a scale — p=0.010
Alzheimer's Disease · Agitation
Primary: NeuroBehavior Rating Scale-- Agitation — 4.33; 5.26 units on a scale — p=0.036
Agitation in Participants With Dementia of the Alzheimer's Type
Primary: Change From Baseline to Week 12 in the Cohen-Mansfield Agitation Inventory (CMAI) Composite Score — 73.7; 68.8; 71.3; -16.2 score on a scale — p=0.789
Agitation · Dementia
Primary: Absolute Change From Baseline in Positive and Negative Syndrome Scale- Excited Component (PEC) Total Score for the First Episode of Agitation — -5.7; -7.5; -5.4 score on…
Schizophrenia
Primary: PANSS-EC Change From Baseline — -4.98; -6.71; -8.56 PANSS units — p=0.0880
Agitation in Patients With Dementia of the Alzheimer's Type
Primary: Stage 1 and Stage 2: Change From Baseline in the Cohen-Mansfield Agitation Inventory (CMAI) Composite Score to Week 6 and Week 12 — 73.9; 72.3; 71.7; -10.7 units on a…
Alzheimer's Disease
Primary: Mean Change From Baseline in the 4-Item Agitation/Aggression Subscale of the Neuropsychiatric Inventory (NPI-4 A/A) at Week 12 — -5.4; -6.2 units on a scale
Schizophrenia
Primary: Change From Baseline to 2 Hours Post the First Intramuscular (IM) Injection in Positive and Negative Syndrome Scale-Excited Component (PANSS-EC) — -4.7; -4.6 units on a…
Emergence Agitation
Primary: Number of Participants With Emergent Agitation — 16; 24 Participants
Alzheimer's Disease
Primary: Alzheimer's Disease Cooperative Study - Clinical Global Impression of Change — 2.5; 2.43 units on a scale
Schizophrenia
Primary: Change From Baseline in Brief Psychiatric Rating Scale (BPRS) Total Scores at 72 Hours — -17.32; -18.44 scores on a scale
Bipolar I Disorder
Primary: Change in PANSS Excited Component (PEC) Score From Baseline Following Dose #1 of Staccato Loxapine, Compared With Placebo — -4.9; -8.1; -9.0 units on a scale — p=<0.0001
Agitation,Psychomotor · Dementia
Primary: Mean Change From Baseline in Positive and Negative Syndrome Scale-Excited Component (PEC) Total Score — -5.4; -7.1; -2.9; -6.8 score on a scale — p=0.0813
Patients With Schizophrenia and Acute Agitation
Primary: Change in PANSS-EC From Baseline — -5.5; -8.1; -8.6 units on a scale — p=0.0004
Agitation · Alzheimer's Disease
Primary: Change in the Neuropsychiatric Inventory (NPI) Agitation/Aggression Domain Score From Day 1 (Stage 1 Baseline) to Day 36 (Stage 2 Baseline) and From Day 36 to Day 70…
Agitation
Primary: Positive and Negative Syndrome Scale - Excited Component — 7.86; 14.93 PANSS SCORE
Bipolar Disorder · Schizophrenia · Agitation,Psychomotor
Primary: Change From Baseline in the Positive and Negative Syndrome Scale- Excited Component (PEC) Total Score — -10.4; -10.0; -10.1; -9.8 score on a scale
Major Depressive Disorder · Irritability
Primary: Change From Baseline to Week 6 in SIS Total Score — -21.13 units on a scale
Brain Injury · Aggression
Primary: Proportion of Participants With >2-point Increase on Neuropsychiatric Inventory - Irritability Domain Rated by Observer Day 28 — 66.3; 66.7 percentage of participants…
Alzheimer's Disease · Apathy · Dementia
Primary: Apathy Evaluation Scale Score at 12 Weeks — 38.2; 43.6 units on a scale — p=<0.05
Alzheimer Disease
Primary: Presence of Agitation and/or Psychosis Measured by the Neuropsychiatric Inventory (NPI) Combined With an Assessment of the Clinical Significance of Behavioral Change…
Agitation Associated With Dementia of the Alzheimer's Type
Primary: Change From Baseline in Cohen-Manfield Agitation Inventory(CMAI) Score at 10 Weeks After Dosing. — -11.7; -15.2; -8.0 units on a scale — p=< 0.0001