N/A N=37 Biobehavioral Pathways Underlying Alcohol Use and Health
Alcohol Use Disorder · Liver Diseases
Primary: Percentage of Screen Eligible Who Enroll — 28; 5 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=60 Acute Alcohol Response In Bipolar Disorder: a fMRI Study
Bipolar Disorder · Alcohol Drinking · Alcohol Use Disorder
Primary: Level of Intoxication (Subjective Response) on Each Condition Day After Drinking Relative to How They Felt When Arriving to the Lab on That Respective Day )Prior to…
Phase 3 N=40 Glutamatergic Modulation of Disordered Alcohol Use
Alcohol Dependence
Primary: Percentage of Participants Demonstrating Alcohol Abstinence in the Control (Midazolam) Group Versus the Active (Ketamine) Group — 68.6; 98.6 percentage of participants
N/A N=131 Neurobiological Responses in Alcoholism and Early Trauma
Alcohol Use Disorder · Early Trauma Complications
Primary: Brain Response — .015; .010; -.013; .08 unitless — p=<0.05
Phase 1 N=26 Citalopram Effects on Craving and Dopamine Receptor Availability in Alcoholics
Alcohol Dependence
Primary: Craving for Alcohol in Alcohol Dependence With Citalopram Compared to Placebo — 21; 30.4; 10.8; 10.6 score on a scale
Phase 2 N=119 Integrated Alcohol Disorder and PTSD Treatment
PTSD · Alcoholism
Primary: Clinician Administered PTSD Scale (CAPS) — 43.2; 42.1; 25.8; 32.9 score on a scale — p=.002
N/A N=123 Contingency Management of Alcohol Abuse in the Severely Mentally ILL
Alcohol Abuse · Schizophrenia · Bipolar Disorder
Primary: Alcohol Use as Assessed by Ethyl Glucuronide Detection in Urine — 408.86; 734.79 EtG Value (nanograms per milileter)
Phase 3 N=75 Aripiprazole for Bipolar Disorder and Alcohol Use Disorder
Bipolar Disorder · Alcoholism · Alcohol Abuse
Primary: Timeline Follow Back (TLFB) — -0.82; -0.71 drinks per drinking day
N/A N=674 STAR*D Alcohol: Treatment of Depression Concurrent With Alcohol Abuse
Major Depressive Disorder · Alcohol Use Disorder
Primary: Quick Inventory of Depression- Self Report 16 — 9.3; 8.9 units on a scale
N/A N=134 Records for Alcohol Care Enhancement
Alcohol Use Disorder (AUD)
Primary: Percent of New Alcohol Use Disorder (AUD) Diagnosis Episodes That Meet Criteria for AUD Treatment Engagement Among Patients With a New AUD Diagnosis Who Are Empaneled to…
Phase 2 N=12 Modafinil for the Treatment of Alcohol Use Disorders
Alcohol Use Disorder
Primary: Time to Relapse — 16; 43 days
Phase 4 N=96 Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders
Alcohol Use Disorder · Bipolar Disorder · Schizoaffective Disorder Bipolar Type
Primary: Baseline-to-Exit Change in Drinks Per Drinking Day (TLFB) — -1.98; -2.82; -1.22 Standard Drinks per Drinking Day
Phase 1 N=19 Behavioral Effects of Drugs: Inpatient (36) (Alcohol, Duloxetine, and Methylphenidate)
Alcohol Use Disorder
Primary: Reinforcing Effects (Pre-Alcohol Dose Consumption) — 0.005; .01; 0.007; 0.005 Units on a Theoretical Scale
N/A N=60 A Response Modulation Hypothesis of Socioemotional Processing Associated With Alcohol Use Disorder
Healthy Volunteers · Alcohol Drinking Related Problems · Alcohol-Related Disorders
Primary: Alcohol Attention Bias Signal - Stage 1 — 0.007121461; 0.135970228; -0.015216812; 0.112620872 Arbitrary units (A.U)
N/A N=392 Individualizing Incentives for Alcohol in the Severely Mentally Ill
Schizophrenia · Bipolar Disorder · Major Depressive Disorder
Primary: Alcohol Use Assessed by Ethyl Glucuronide (EtG) Detection in Urine — 0.66; 0.65; 0.61 proportion uEtG negative
Phase 4 N=4,985 Alcohol Research Consortium in HIV-Intervention Research Arm
HIV Positive · Alcohol Use
Primary: Audit-C Score on a Scale — -1.0; -2.3; -1.0 score on a scale
Phase 2 N=52 Ibudilast and Withdrawal-Related Dysphoria
Alcohol Use Disorder
Primary: Negative Affect — 2.91; 2.47 units — p=.62
N/A N=200 Women's Treatment and Early Recovery
Substance-related Disorders
Primary: Treatment Completion — 43; 31 Number of women — p=<0.05
Phase 2 N=151 Concurrent Alcohol and Smoking Treatment: Effects on Alcohol Relapse Risk
Tobacco Use Cessation · Alcohol-related Disorders
Primary: Smoking Abstinence — 20; 1 participants — p=<.01
Phase 2 N=7 Treatment of Young Adults With Comorbid AUD/MDD: A Pilot Medication Trial
Major Depressive Disorder · Alcohol Use Disorder
Primary: Drinks Per Drinking Day — 2.8; 2.0 Drinks per drinking day
N/A N=16 Pilot Study on Training Emerging Adults Skills in Navigating College
Alcohol Abuse · Cognitive Deficit in Attention
Primary: Participant Retention — 85.71; 88.89 percentage of participants
Phase 4 N=41 Disulfiram Combined With Lorazepam for Alcohol Dependence and Anxiety Disorder
Alcohol Dependence · Anxiety Disorder
Primary: Treatment Adherence — 15 Participants
N/A N=303 The Impact of Alcohol Consumption on Tuberculosis Treatment Outcomes
Tuberculosis · Alcohol Consumption · Treatment Adverse Effect
Primary: Time to Culture Conversion — 5.6; 5.4; 5.5 weeks
N/A N=75 Transdiagnostic CBT for Comorbid Alcohol Use and Anxiety Disorders
Alcohol Use Disorder · Anxiety Disorders
Primary: Mean Number of Drinks Consumed Per Week — 40.82; 29.62; 12.12; 23.86 Standard Drinking Units per Week — p=0.002
N/A N=105 Neurobiology of Alcohol and Nicotine Co-Addiction
Alcohol Use Disorder · Nicotine Use Disorder
Primary: Brain Activation During Functional Magnetic Resonance Imaging (fMRI) in Response to a Stress Modulated Cue Induced Craving Task (DSNBACK) — -26.1562; -45.2123; 18.4989…
Phase 2 N=46 Varenicline to Reduce Alcohol Consumption in Heavy Drinkers
Alcohol Drinking
Primary: Alcohol Consumption — 92.0; 77.3 mg/%
Phase 2 N=69 Combined Treatment for Alcohol-Dependent Individuals With PTSD
Stress Disorders, Post-Traumatic · Alcohol Abuse · Substance-Related Disorders
Primary: Heavy Drinking Days/Week — 3.13; 2.89; 1.05; 0.48 Days/Week — p=0.34
N/A N=5,706 Computerized Substance Use and Depression Screening and Behavioral Treatment in HIV Primary Care
Substance Use Disorders · HIV · Depression
Primary: Change in Mental Health and Substance Use Screening Rates — 2008; 2379 Participants
N/A N=287 Dual Diagnosis Self-Help Referral
Dual Diagnosis
Primary: Psychiatric Functioning at 6 Months — .333; .387 units on a scale
N/A N=75 Clinical Intervention in Alcohol Use Disorder
Alcohol Use Disorder · Eligible to go Into the MRI Scanner · Short-term Abstinence From Alcohol Use (2 Week Abstinent)
Primary: Intervention Effects on Brain Functional Connectivity — 0.05; 0.19 percentage of Blood Oxygenation Level De