Clinical Trial Search

Primary: Determine the Difference Between Acute Effect of a Mixed Meal on Radial Artery Stiffness in Subjects With Type I Diabetes Mellitus Who do and Who do Not Take an…

Primary: Carotid Femoral Pulse Wave Velocity (cfPWV) — 8.71; 7.8; 8.28 m/s

Primary: Copeptin Levels — 8.3 pmol/L

Primary: Postprandial Pulse Wave Velocity (PWV) in Type 2 Diabetes Mellitus (T2DM) Participants at 30 Minutes (Mins) Pre-Breakfast — 10.99; 10.73; 11.56; 11.31 meters per second…

Primary: LDL-C Levels Assessed at Randomization and 6 Months — 128; 87; 126; 133 mg/dL — p=<0.0001

Primary: Differences in Pulse Wave Velocity at Baseline and 3, 6 and 12 Months After Treatment With Metformin or Agonist GLP-1R. — 11.8; 11.2; 11.6; 11.5 m/s

Primary: Change in Insulin Sensitivity — 12.2; -2.4 (mg/kg/min)/(insulin) — p=0.005

Primary: Percent Time in the Optimal Glucose Range — 71.20; 62.51 percentage of time — p=<0.001

Primary: Pulse Wave Velocity (m/s) — 8.81; 7.36; 5.53 m/s

Primary: Linear Relationship Between HOMA-IR and Cognitive Function (R-squared) — 0.205; 0.299; 0.738; 0.0264 R-squared — p=0.162

Primary: Change From Baseline in Reactive Hyperemia Index at 5 and 10 Months — 1.9; 1.5; 2.01; 1.55 arbitrary units — p=<0.05

Primary: Percentage of Time in Target Range of 70-180 mg/dL. — 49.64; 48.86; 60.78; 50.1 percent time spent 70 mg/dL - 180 mg/dL

Primary: Hemoglobin A1c — 7.988; 8.025 A1c percentage

Primary: Coronary Blood Flow Assessment With Regadenoson Stress by Cardiac MRI Between Non-diabetic and Type 1 Diabetic Subjects. — 2.19; 1.81; 1.95 percentage of StressMBF/ Rest…

Primary: Glycemic Variability — 2.00; 3.91 percent

Primary: Arterial Stiffness — -0.26; -0.22 m/s

Primary: Glygocalyx Integrity - Perfused Boundary Region — 0.11; -0.16 Delta micrometers (mcm)

Primary: Change in Percentage Overweight — 1.92; 1.91 change in percent overweight

Primary: Hemoglobin A1c — 9.0; 9.0 Percentage of glycated hemoglobin

Primary: Non-dominant Wrist-worn Actigraph to be Worn 24/7 (Spectrum Plus) — 18; -25.8 min per night — p=0.0227

Primary: Percentage of Enrolled of Eligible Participants Screened — 42 Participants

Primary: Hemoglobin A1c — 9.6; 9.8; 8.5; 10.9 Percentage (%) of glycated hemoglobin — p=.219

Primary: Insulin Sensitivity — 8.6; 6.2; 5.8; 4.8 mg/kg/min

Primary: C-peptide Area Under the Curve (AUC) — 0.57; 0.60; 0.66; 0.60 (pmol/ml)*minutes — p=0.89

Primary: Change From Baseline Hemoglobin A1c — -0.5 A1c percentage points

Primary: Feasibility: Response Rate — 4; 4 number of participants

Primary: Glycemic Control (A1C) — 8.60; 9.35 percentage of glycosylated hemoglobin — p=0.593

Primary: Barriers to Diabetes Adherence Questionnaire-Youth Report Stress/Burnout Subscale — 2.36; 2.31 score on a scale

Primary: Time in Range (TIR) — 50.1; 47.2; 53.8; 50.3 Percent of time — p=.224

Primary: A1C — 8.7; 8.6 percentage of glycosylated hemoglobin