N/A N=39 Beta Events and Sensory Perception
Beta Rhythm · Tactile Perception
Primary: Threshold-Level Tactile Detection Hit Rate — 0.37; 0.46; 0.47; 0.32 # hit trials/(total # hit + miss trials) — p=0.0031
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=13 Examining the Effect of EEG-guided Theta Burst Stimulation in Bipolar Disorder
Bipolar Disorder
Primary: Brain Activity (Beta Power) in Left vLPFC — -88.78; 1437.64; 13.43; -128.00 Percentage of change post versus pre — p=0.29389090
N/A N=58 Modulation of Cognitive Control Signals in Prefrontal Cortex by Rhythmic Transcranial Magnetic Stimulation
Executive Function
Primary: Number of Remembered Items — 1.863; 1.754; 1.796; 1.797 number of remembered items — p=0.263
N/A N=39 Theta Connectivity in Working Memory
Executive Function
Primary: Number of Remembered Items — 1.72; 1.68; 1.68; 1.65 remembered items — p=0.783
N/A N=24 Investigating Electroencephalographic Predictors of Default Mode Network Anticorrelation in Healthy Adults
Healthy
Primary: Association Between EEG Measurements and Default Mode Network Brain Activity Measured With fMRI — 0.09 Spearman rank correlation coefficient
N/A N=25 Measuring Plasticity in SFC/dACC Following Theta-Burst-Stimulation Using TMS
Cognitive Control
Primary: Post vs. Pre Change in Mid-frontal Theta Oscillations for iTBS vs. cTBS Stimulation — -0.043; 0.017 microVolts (uV) at FCz EEG electrode
N/A N=13 EEG Changes With Guided Online Meditation
Meditation
Primary: Number of Participants With EEGs to Measure Changes in Wave Oscillations — 3; 4 Participants with Evaluable EEGs
N/A N=25 Theta Burst Stimulation in Young Adults With Depression
Depression
Primary: Dorsomedial Prefrontal Cortex Activation — 0.16; 1.35; 0.36 score in arbitrary units — p=0.80
Phase 3 N=28 EEG Synchronized TMS Trial for Depression
Depression
Primary: Remission Rate — 2; 3 Participants — p=0.6
N/A N=52 Rhythmic Light Therapy for Alzheimer's Disease Patients
Mild Cognitive Impairment
Primary: Change in Electroencephalography (EEG) Power at 40 Hertz (Hz) — 3.54; 5.28; 2.83; 4.10 μV2/Hz
Phase 1 N=157 Teen Brain Training (TBT)
Suicide, Attempted · Suicide, Ideation · Depression
Primary: Columbia Suicide Severity Rating Scale (CSSRS) - Visit 1 — 2.08; 2.37 points
N/A N=9 TMS Alteration of the Reward Positivity
Anhedonia
Primary: Reward Positivity — 2.21; .29 femtoteslas
N/A N=8 Theta Burst Stimulation for Alcohol Use Disorder
Alcohol Use Disorder
Primary: Change in Penn Alcohol Craving Scale — 11.50; 11.75; 8.25; 7.25 units on a scale
N/A N=14 Feasibility of Gamma Transcranial Alternating Current Stimulation to Reduce Beta-amyloid Load and Improve Memory
Mild Cognitive Impairment
Primary: Side Effects — 0.53 units on a scale
N/A N=10 Stimulating Neural Activity to Improve Blood Flow and Reduce Amyloid: Path to Clinical Trials
Alzheimer Disease
Primary: Percentage of Adherence to Daily Device Use — 95.55; 95.37 percentage of adherence to treatment
N/A N=65 Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms
Bipolar Disorder · Major Depressive Disorder · Mood Disorders
Primary: Mean Score Measuring Suicidal Ideation/Propensity (SI/P) Using Concise Health Risk Tracking Scale-Self Reported (CHRT-SR) to Assess for Propensity — 12.83; 12.41; 10.84…
N/A N=231 Mind-body Awareness Training and Brain-computer Interface
Healthy Subjects
Primary: BCI Performance Change From Baseline — 16.87; 7.9 Percent valid correct (PVC) — p=0.003
Phase 4 N=26 Beta Blockade in in Traumatic Brain Injury
Brain Injuries, Traumatic
Primary: Mortality — 7.7; 33.3 percentage of participants
N/A N=60 Brain Emotion Circuitry-Targeted Self-Monitoring and Regulation Therapy (BE-SMART)
Mood Disorders
Primary: Functional Magnetic Resonance Imaging (fMRI) Blood Oxygen-level Dependent (BOLD) Signal Changes in Left Amygdala at Baseline and at the End of the Intervention — 1.62…
N/A N=26 Effect of Cross Frequency tACS on Cognitive Control
Cognitive Control · Executive Function
Primary: Reaction Time for Trials With High Abstraction Relative to Low Abstraction — 0.1247; 0.1444; 0.1022 seconds — p=0.031
N/A N=90 The Influence of Age on EEG Signals and Consciousness During Anesthesia
Anesthesia
Primary: BIS50 — 70.9; 74.7 index
N/A N=22 Transcranial Magnetic Stimulation for BECTS
Benign Epilepsy With Centrotemporal Spikes · Language Problems · Learning Disorders
Primary: Interictal Epileptiform Discharge (IED) Frequency — 0; 0; 0; 0 IEDs per 5 minutes — p=0.04
N/A N=7 Pilot Accelerated Theta Burst in Treatment-Resistant Bipolar Depression
Treatment Resistant Depression
Primary: Change From Baseline Montgomery Asberg Depression Rating Scale (MADRS) — 40.0; 5.7 score on a scale
N/A N=37 Sound and Music for Mild Cognitive Impairment
Mild Cognitive Impairment
Primary: Episodic Memory Assessed by the Cogstate Alzheimer's Battery — -0.0746; 0.0700; 0.0593; 0.5137 z score
N/A N=30 Augmenting Single-session Behavioral Activation (BA) With Delta-beta Transcranial Alternating Current Stimulation (tACS) for the Treatment of Depression
Major Depressive Disorder
Primary: Clinician-rated Depressive Symptoms — 19.33; 19.93; 11.33; 13.93 score on a scale — p=0.34
N/A N=35 Investigating the Causal Role of Prefrontal Control in Decision-making in Patients With Anhedonia
Major Depressive Disorder · Anhedonia
Primary: Change in the Percentage of Trials That the Participant Chooses to Perform the Hard Task — -0.30; -0.22; -0.09 percentage of trials — p=0.049
N/A N=30 BIS and Entropy in Deep Brain Simulation
Movement Disorders · Depth of Anesthesia Monitors
Primary: Correlation Between Bispectral (BIS) and Response Entropy (RE) Indices — 96; 96; 65; 77 units on a scale
N/A N=20 Effect of tACS Stimulation on Alpha Oscillations
Healthy
Primary: Salivary Alpha Amylase — 0.00695; 0.03055 log-normalized percent change of U/mL — p=0.70
N/A N=12 rTMS and Botulinum Toxin in Benign Essential Blepharospasm
Benign Essential Blepharospasm
Primary: Change in JRS Severity Score — -1.8; -0.1 Change in score
N/A N=20 Measurement of Bispectral Index and Awareness in Patients Undergoing Electrophysiology Studies With Isoproterenol
Intraoperative Awareness
Primary: Number of Participants With an Increase in BIS Readings During Steady State — 19 participants