Phase 4 N=70 The Effect of Intra-articular Bilateral Knee Injections of Zilretta on Performance Measures in Adults With Knee OA
Knee Osteoarthritis
Primary: 30 Second Chair Standing Test — 9.5 stands
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=80 Knee Bracing for People With Patellofemoral Osteoarthritis
Knee Osteoarthritis
Primary: Change in Pain on the VIsual Analog Scale (VAS) — -.068 change in units on a scale from baseline
Phase 2 N=157 Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee
Osteoarthritis, Knee
Primary: Change From Baseline in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Domain Score at Week 2 — -3.64; -3.15 Units on a scale — p=0.39
N/A N=79 Gait Modification Treatment for Knee Osteoarthritis
Knee Osteoarthritis
Primary: Change From Baseline to Week 17 and From Baseline to Week 21 in Pain as Measured by Numerical Rating Scale — -2.1; -1.8; -2.2; -1.5 units on a scale — p=0.495
N/A N=100 Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement
Osteoarthritis of the Knee
Primary: Change in KOOS4 From Baseline (Knee Injury and Osteoarthritis Outcome Score) — 16.0; 32.5 units on a scale
N/A N=40 Muscle Property, Alignment and Joint Loading in People With Knee Osteoarthritis
Osteoarthritis, Knee
Primary: Change of External Knee Adduction Moment as Assessed by Visual Motion Analysis System — 0.50 Nm/kg
N/A N=23 In Vivo Three-Dimensional Determination of Osteoarthritis Brace Effectiveness
Osteoarthritis, Knee
Primary: Medial Condylar Separation With Brace — 0.60 mm
N/A N=34 Knee Biofeedback Rehabilitation Interface for Game-based Home Therapy for Patients With Knee Osteoarthritis
Osteo Arthritis Knee
Primary: Change in Knee Injury and Osteoarthritis Outcome Score (KOOS) — 3.3; 8.9; 4.6; 9.7 score on a scale — p=<0.05
N/A N=64 Needling Techniques for Knee Osteoarthritis
Knee Osteoarthritis · Kidney Yin Deficiency · Kidney Yang Deficiency
Primary: WOMAC Total in Week 15 — 11.6; 54.4 score on a scale — p=<0.001
N/A N=3,000 Development of an Osteoarthritis (OA) Care Plan to Improve Process and Quality of OA Treatment Decisions
Osteo Arthritis Knee · Osteoarthritis, Hip
Primary: Differences in Decision Conflict Scale With ASK vs Usual Care — 25.1; 26.0 Score on a scale
N/A N=99 Time-dependent Improvement of Functional Outcome Following Oxford Medial Unicondylar Knee Replacement
Osteoarthritis
Primary: Knee Injury and Osteoarthritis Outcome Score — 85.5; 88.2 units on a scale
N/A N=51 Efficacy Study of an Unloading Brace for Knee Osteoarthritis
Osteoarthritis of the Knee
Primary: Knee Injury and Osteoarthritis Outcome Score (KOOS) Pain Score — 2.92; 2.86; 3.03; 2.67 units on a scale — p=<0.05
N/A N=27 Muscle Weakness and Post-traumatic Knee OA
Meniscectomy
Primary: Change in International Knee Documentation Committee (IKDC) Subjective Knee Form Score — 22.2; 20.6 units on a scale
Phase 3 N=380 Effect of Diacerein vs Celecoxib on Symptoms and Structural Changes in Symptomatic Knee Osteoarthritis
Osteoarthritis · Osteoarthritis, Knee
Primary: Change Form Baseline in WOMAC A Pain Subscale — -11.14; -11.82 cm — p=<0.025
Phase 3 N=164 A Study on Visco-antalgic Intra-articular Administration in Symptomatic Knee Osteoarthritis
Knee Osteoarthritis
Primary: Change From Baseline in WOMAC VA3.1 Pain Subscale Score at Month 6 — -23.6; -14.1 mm — p=0.141
N/A N=31 A Biomechanical Exercise Program for Knee OA
Osteoarthritis, Knee
Primary: Change in Lower Extremity Function — 10.6; 7.6; -6.4 Change in scores on a scale
N/A N=76 Home Rehabilitation in Patients After Primary Total Knee Arthroplasty
Osteoarthritis · Rehabilitation
Primary: Total WOMAC Score — 51.64285714; 52.47619048; 39.60714286; 40.38095238 score on a scale
N/A N=100 Structured Non-operative Treatment of Knee Osteoarthritis
Osteoarthritis of the Knee
Primary: Change From Baseline in KOOS4 (Knee Injury and Osteoarthritis Outcome Score) — 18.2; 7.1 units on a scale
N/A N=60 Energy Dispersive Bracing for Conservative Treatment of Knee Osteoarthritis
Knee Osteoarthritis · Arthritis
Primary: Assessment of Pain Using the Visual Analog Scale — 48.7; 62.6; 50.8; 27.1 score on a scale
N/A N=1,261 Survey of Osteoarthritis Real World Therapies (MK-0663-140)
Osteoarthritis
Primary: Percentage of Participants Who Reported Adequate vs. Inadequate Pain Relief at Baseline — 46.2; 53.8 Percentage of Participants
N/A N=345 STepped Exercise Program for Knee OsteoArthritis
Osteoarthritis, Knee
Primary: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) — -4.85; 0.26; -3.97; -2.53 units on a scale — p=0.0003
Phase 2 N=44 Effectiveness of Minimally Invasive Total Knee Replacement in Improving Rehabilitation and Function
Osteoarthritis
Primary: Quadriceps Muscle Force — 1.27; 1.37; 0.79; 0.66 Nm/kg — p=0.07
Phase 1 N=8 Safety, Tolerability and Pharmacokinetics of Intraarticular 4P004 Single Dose in Patient With KL 2-4 Osteoarthritic Knee
Knee Osteoarthritis
Primary: Safety and Tolerability of Single IA Administration of 4P-004 at Escalating Doses in Participants With Knee OA. — 5; 5; 5; 6 participants
N/A N=80 Trial of Realignment Therapy for Treatment of Medial Knee Osteoarthritis
Knee Osteoarthritis
Primary: Mean Change WOMAC Pain Scale (Most Symptomatic Treated Knee) — -2.2; -1.7 units on a scale change from baseline
N/A N=144 Intra-articular Polyacrylamide Hydrogel in Knee Osteoarthritis
Osteoarthritis
Primary: Change of the Total WOMAC Score (WOMAC-T) — -624.12; -444.82; -605.61; -426.31 score on a scale — p=0.00030
N/A N=24 Group Physical Therapy for Knee Osteoarthritis
Osteoarthritis
Primary: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) — 43.3; 34.1 units on a scale
Phase 3 N=231 Duloxetine Versus Placebo for Osteoarthritis Knee Pain
Osteoarthritis Knee Pain
Primary: Weekly Change From Baseline in the 24-Hour Average Pain Rating Using an 11-Point Numerical Likert Scale Patient Diary — -0.36; -0.84; -0.95; -1.54 units on a scale…
N/A N=93 Wearable LITUS Device for Osteoarthritis of the Knee: a Randomized Double-Blind Placebo-Controlled Trial
Knee Osteoarthritis
Primary: Pain on the Numeric Rating Scale (NRS) Change From Baseline to Study Conclusion — -1.96; -0.85 units on a scale
Phase 2 N=350 A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis
Knee Osteoarthritis · Medial Compartment Knee Osteoarthritis
Primary: Change From Baseline in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Scores of the Index Knee at Week 16 — -8.9; -9.2; -11.8; -10.1 score…
Phase 4 N=120 Colchicine for the Treatment of Osteoarthritis of the Knee
Osteoarthritis · Osteo Arthritis Knee
Primary: Change in Visual Analog Scale (VAS) Pain Score — -1.45; -1.16 score on a scale