Clinical Trial Search

Primary: Change in Concentration of Oxygenated Hemoglobin Between Pre-drug and Post-drug Scans of Patients Completing the N-back Task. — 0.00000000042; -0.00000000126…

Primary: Peak Activity Volume: Right D1 Attempt Movement Activity at S1 - SCI — 893.6 mm^3

Primary: Clinician Administered HAM-D — 27.0; 26.2; 22.0; 22.7 units on a scale

Primary: Depressive Symptoms at 4 Weeks — 15.6; 15.6 units on a scale — p=0.16

Primary: Hamilton Depression (HAM-D) and Anxiety (HAM-A) Rating Scales — 20.07; 21.36; 1; 14.07 units on a scale

Primary: Number of Head Images Successfully Collected — 10 Images

Primary: Brain Oxygenation Level Dependent Signal in the Fusiform Gyrus and the Amygdala on Concerta vs. Placebo — 1.79; 0.58; 1.43; 0.77 Face-Shape BOLD signal difference

Primary: Remission Defined as Hamilton Depression Rating Scale-17 Score of Less Than or Equal to 7 at 12 Weeks — 12; 12 participants

Primary: Activations in Different Cortical Regions Caused by Emotionally Evocative Task — -0.021; 0.084; 0.021; -0.030 Voxels

Primary: Distribution Volume (VT) — 1.27; 1.54; 1.14; 1.31 mL/cm^3 — p=0.02

Primary: Change in Functional Connectivity Measured by Resting MRI — 0.103399365; -0.7637409 correlation coefficients

Primary: Cognition on the RBANS (Repeatable Battery for the Assessment of Neuropsychological Status) Scale — 7; 5.25; -1.5; -1.33 units on a scale

Primary: Change in Right Insula-dorsomedial Frontal Cortex Functional Connectivity Strength. — 93.2; 97.8 percent change from baseline — p=0.981

Primary: Depression Severity Measured by the Hamilton Depression Rating Scale (24-Item) — 18.2 units on a scale

Primary: Change From Baseline in Percent of Trained Items Correctly Repeated — 6.67 d2 treatment effect size

Primary: Resting State Functional Connectivity — 26.2; 23.3 global efficiency percentage — p=0.04

Primary: Post-Lithium Treatment Hamilton Depression Rating Scale (HDRS) — -44.49 Percent Change in HDRS-24 Score

Primary: Average Correlations Between Average Time Series - Left & Right Hemisphere of the Brain — 0.9; 0.92 correlation coefficient (r) — p=< 0.001

Primary: Sensitivity of Pathological Findings (Full Analysis Set) — 0.66; 0.68 Proportion of participants

Primary: Relationship Between Prefrontal Cortex Activation and Respiratory Sinus Arrhythmia — -0.064; 0.00375 Micro mol per second — p=0.008

Primary: Columbia Suicide Severity Rating Scale (CSSRS) - Visit 1 — 2.08; 2.37 points

Primary: Memory Test Accuracy on Trained Stimuli — 53.9; 37.6; 48.9; 37.3 Percent correct

Primary: Neurometabolites Based on Magnetic Resonance Spectroscopy (MRS) — 19.38; 18.94; 27.83; 24.95 arbitrary units

Primary: Relative Changes in Corticolimbic Functional Connectivity as a Result of TMS — -0.11; -0.19 Fisher transformed z values

Primary: Change in Dopamine Levels at Baseline and After Drug of Dependence Administration as Confirmed by PET Images. — 0.0388; 0.033; 0.0285; 0.0368 mm^3

Primary: Performance on Trail-making Test, Part B — -0.02; 0.18 z-score — p=< 0.04

Primary: Change in % Blood Oxygenation Level Dependent Change (%BOLD) in the Nucleus Accumbens — -0.08 %BOLD signal change

Primary: National Institutes of Health Stroke Scale (NIHSS) — 3.8; 2.7 score on a scale

Primary: Signal Change in Functional Magnetic Resonance Imaging (fMRI) BOLD Signal Between Response Inhibition Trials and Control Trials in Right Inferior Frontal Cortex (rIFC)…

Primary: HAM-D 17 (Hamilton Depression Rating Scale) — 1.0; 18.5 Units on a scale