N/A N=29 Calcium Absorption in Patients With Rothmund-Thomson Syndrome
Rothmund-Thomson Syndrome
Primary: Bone Density (Low Areal Bone Mineral Density (aBMD)) — -1.3; -0.9; -2.4; -1.2 z-score
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=18 Enhancing Skeletal Adaptations to PTH and Exercise
Exercise · Bone Resorption · Bone Formation
Primary: Change in C-terminal Peptide of Type 1 Collagen (CTX) — 0.03; 0.03; 0.05; 0.03 ng/mL
Phase 4 N=53 Effect of Calcium + Vitamin D Supplementation on Weight Management in Very-low Calcium Consumers
Obesity · Overweight
Primary: Change in Body Weight — -3.9; -3.5 kg — p=0.441
N/A N=12 PTH And Calcium Responses to Exercise in Older Adults Experiment 2 (PACE Sr. 2)
Osteoporosis
Primary: Change in Parathyroid Hormone (PTH) — 8.5; 20.0 pg/mL
N/A N=36 Health Benefits of Vitamin D and Calcium in Women With PCOS (Polycystic Ovarian Syndrome)
Polycystic Ovarian Syndrome · Vitamin D Deficiency
Primary: Serum HbA1C at 3 Months — 5.55 percentage
Phase 2 N=241 Adding Phosphorus to Osteoporosis Drug Treatment
Osteoporosis · Osteopenia
Primary: Lumbar Spine and Hip BMD, Measured as Grams Per Square Centimeter. — 0.76; 0.78; 0.88; 0.86 g/cm2
Phase 4 N=230 Treatment of Vitamin D Insufficiency
Vitamin D Deficiency
Primary: Intestinal Calcium Absorption — 0.200; 0.217; 0.183; 0.206 Total Fractional Calcium Absorption
Phase 4 N=19 Does Treatment of Hypovitaminosis D Increase Calcium Absorption?
Osteoporosis · Osteopenia · Vitamin D Deficiency
Primary: Change in Intestinal Calcium Absorption From Baseline to One Month — 3 percent calcium absorption
N/A N=22 Calcium Retention as Influenced by Dietary Components That Induce an Acid Load
Healthy
Primary: Calcium Absorption — 30.4; 25.4 percentage of Calcium-47 absorbed — p=0.02
Phase 3 N=47 Calcium and Vitamin D to Optimize Bone Mass in Boys With Risperidone-induced Hyperprolactinemia
Risperidone-induced Hyperprolactinemia
Primary: Trabecular Bone Mineral Density in the Ultradistal Radius — 192.9; 197.2; 191.0; 194.6 mg/cm^3
N/A N=129 Ca:Mg Ratio and Cognitive Function
Cognitive Function
Primary: Overall Score Changes From Baseline by Magnesium Treatment vs. Placebo — 1.1; 0.6 score on a scale — p=0.20
N/A N=55 Effects of Gastric Bypass Surgery and Calcium Metabolism and the Skeleton
Obesity, Morbid · Gastric Bypass
Primary: Change in Intestinal Calcium Absorption — -25.8 % of ingested calcium that is absorbed
N/A N=12 Calcium and Phosphorus Balance and Calcium Kinetics in Patients With Stage 3/4 Chronic Kidney Disease
Chronic Kidney Disease
Primary: Calcium Balance — 61; 508 mg/d calcium
Phase 1 N=27 Effect of Calcium 500 mg and Vitamin D3 1000 IU Chewable Tablet on Intestinal Calcium Absorption
Healthy Volunteers
Primary: PTH AUC(0-6): Area Under the Serum Concentration-Time Curve From Time 0 to 6 Hours for Parathyroid Hormone — 215; 157 hour*picogram per milliliter (hr*pg/mL)
Phase 1 N=55 Human Pharmacology Trial of Calcium-vitamin D3 Tablet in Healthy Participants
Calcium Deficiency · Vitamin D Deficiency
Primary: Amount of Calcium Excreted in Urine From 0 Hours up to 6 Hours Post Dose (Ca2+ Ae0-6h) — 1.07; 0.63 mmol
Phase 4 N=23 Does Omeprazole Decrease Intestinal Calcium Absorption?
Osteoporosis · Achlorhydria · GERD
Primary: Change in Intestinal Calcium Absorption From Baseline to One Month — 5 percent calcium absorption
Phase 4 N=80 Impact on Reducing the Incidence of Low Serum Calcium by Providing Educational Materials on the Need to Take Daily Supplemental Calcium and Vitamin D to Patients With Paget's Disease Treated With Reclast®
Paget's Disease of the Bone · Hypocalcemia
Primary: Percentage of Patients With Serum Calcium <2.07 mmol/L at 9-11 Days After Receiving Zoledronic Acid. — 1.3; 0.0 percentage of patients
N/A N=3 Calcium and Phosphorus Whole-Body Balance and Kinetics in Patients With Moderate Chronic Kidney Disease
Phosphorus and Calcium Disorders · Chronic Kidney Disease Mineral and Bone Disorder · Chronic Kidney Diseases
Primary: Fractional Calcium Absorption — 0.30; 0.42 fraction of 1.00
N/A N=22 Impact of Vitamin D Supplementation on Lactation Associated Bone Loss
Osteoporosis
Primary: Change in Bone Mineral Density (BMD) in HIP at 6 Months — -0.041; 0.011 grams/cm^2
Phase 4 N=29 Vitamin D Repletion in Stone Formers With Hypercalciuria
Nephrolithiasis · Urolithiasis · Idiopathic Hypercalciuria
Primary: Change in 24 Hour Urine Calcium — 2 mg/day
Phase 4 N=12 Do Aromatase Inhibitors (AIs) Decrease Intestinal Calcium Absorption?
Breast Cancer · Osteoporosis · Osteopenia
Primary: Change in Intestinal Calcium Absorption Related to Aromatase Inhibitor Therapy — 16 percent calcium absorption
Phase 4 N=12 The Effect of Protein on Calcium Absorption and Gastric Acid Production
Osteoporosis
Primary: Percent Change in Intestinal Calcium Absorption — 34.2; 31.5 percentage of calcium absorption
Phase 2 N=23 The Role of Parathyroid Hormone (PTH) in Low Bone Mass in Anorexia Nervosa
Anorexia Nervosa · Osteoporosis
Primary: Percent Change in Lumbar Spine Bone Mineral Density — 5.6; 0.2 percentage of change — p=< 0.01
Phase 3 N=120 Calcium Chloride for Prevention of Blood Loss During Intrapartum Cesarean Delivery
Uterine Atony · Uterine Atony With Hemorrhage · Postpartum Hemorrhage
Primary: Quantitative Blood Loss — 840; 1051 milliliters — p=<0.05
N/A N=17 Effects of Calcium and Phytate on Zinc Absorption
Dietary Zinc Absorption
Primary: Zinc Absorption — 32.8; 26.9; 39.4; 26.2 Percentage of Zinc-65 absorbed — p=0.17
Phase 2 N=40 Calcium Chloride for Prevention of Uterine Atony During Cesarean
Uterine Atony · Uterine Atony With Hemorrhage · Cesarean Section Complications
Primary: Uterine Atony — 4; 10 Participants
N/A N=9 Tumor Necrosis Factor Decreases Vitamin D Dependant Calcium Absorption
Rheumatoid Arthritis · Crohn's Disease
Primary: Intestinal Absorption of Calcium
Phase 2 N=92 Vitamin D and Calcium Homeostasis for Prevention of Type 2 Diabetes
Glucose Intolerance · Type 2 Diabetes Mellitus · Metabolic Syndrome
Primary: Chang in Disposition Index, a Measure of Beta Cell Function — 287; 314; -122; -129 units on a scale
N/A N=82 IGF-1 and Bone Loss in Women With Anorexia Nervosa
Anorexia Nervosa · Osteopenia · Osteoporosis
Primary: Postero-anterior Spine Bone Mineral Density by DXA — 0.891; 0.887; 0.874 g/cm2 — p=0.03
Phase 3 N=68 Bone Properties in Hypoparathyroidism: Effects of PTH
Hypoparathyroidism
Primary: Requirements for Calcium Supplementation — 3.03; 1.66 grams per day of calcium supplementation