N/A N=54 Food Intake Response to Short-Term Modifications of Metabolism in Humans
Healthy Volunteers
Primary: 24-hour Energy Expenditure (kcal) — 2256; 2166; 2563; 2487 kcal
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=15 Effect of Caloric Restriction and Protein Intake on Metabolism and Anabolic Sensitivity
Weight Loss · Starvation
Primary: Change in Resting Metabolic Rate — -63.4; -77.6; -47.4 kcal change
N/A N=47 Females, Aging, Metabolism, and Exercise
Obesity
Primary: Change in Physical Activity Energy Expenditure (PAEE) — 74.5; -10.2; 61.0 kcal/day
Phase 3 N=31 Thyroid Hormones Homeostasis and Energy Metabolism Changes During Stimulation of Endogenously Secreted Bile Acids (BAs)
Healthy Volunteers
Primary: Energy Expenditure — 1.37; 1.40; 1.28; 1.27 kcal/min — p=0.0001
N/A N=21 Effects of Low Fat Versus Low Carbohydrate Diets on Energy Metabolism
Healthy · Healthy Volunteers
Primary: Ad Libitum Energy Intake — 2752; 2063 kcal per day
N/A N=87 Assessment of Energy Balance
Caloric Intake and Energy Metabolism
Primary: ENERGY BALANCE EQUATION, PHASE I, ONE SUB-STUDY — 2360; 2208; -152 kCal
N/A N=39 Effect of Caloric Restriction on Fat Oxidation in Obese Men and Women (Magellan II)
Obesity · Overweight · Metabolic Diseases
Primary: Change From Baseline Amount of Fat Oxidation at 14 Days — 0.91; 0.94 Fold change of RQ ratio
N/A N=60 Dietary Carbohydrate Manipulation and Energy Balance: RCT
Physical Activity · Diet Modification
Primary: Physical Activity Energy Expenditure (kJ/Day or kcal/Day) — 1229; 1096; 1275; 1142 kcal/d
N/A N=20 The Effects of Exercise on Dietary Intake
Active Lifestyle Males · Inactive Lifestyle Males
Primary: Energy Intake at the Meal (Exercise Session) — 1105.6; 934.8 kilocalories
N/A N=113 Effect of Infant Formula on Energy Balance
Development
Primary: Growth, Weight for Length (WLZ) Z Scores — -0.26; -0.12; -0.12; 0.13 Z score — p=<0.05
N/A N=20 Timing of Caloric Intake, Diet-induced Thermogenesis and Hormonal Pattern
Diet-induced Thermogenesis
Primary: Intra-individual Variation in Morning Diet-induced Thermogenesis (DIT) Evaluated by Calorimetric Exam After the Consumption of a Meal at 8:00 am Compared With Evening…
N/A N=198 The Comparison of Energy in Take and Body Weight EXERCISE
Exercise · Energy · Body Weight
Primary: A Comparison of the Effects of Energy Balance With Three Groups. [Energy Intake, Adjusted DLW] — 123.6; 90.7; -2.3 kcal/day
N/A N=32 Impaired Regulation of Energy Balance in Elderly People (Balance Study)
Anorexia of Ageing
Primary: Energy Intake Compensation — 1; 1 MJ/day
N/A N=218 CALERIE: Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy
Aging
Primary: Change in Core Body Temperature, Baseline to 12 Months — -0.05; -0.03 degrees Celsius — p=0.70
Phase 3 N=32 Behavioral Mechanism of Energy Compensation With Exercise
Obesity · Weight Loss · Eating Behavior
Primary: Attentional Bias — 48.85 percentage of time fixated on food cues
Phase 2 N=13 Energy Metabolism in Thyroidectomized Patients
Thyroid Goiter · Hypothyroidism · Thyroid Cancer
Primary: Short Term Change in Weight — 1.7; -0.76 Kilogram
Phase 3 N=80 Hypocaloric Nutrition in Critically Ill Patients
Critically Ill
Primary: SOFA (Sequential Organ Failure Assessment) Score — 0.7; 1.7 units on a scale
Phase 2 N=47 Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate
Healthy Volunteers
Primary: Resting Energy Expenditure at Low Temperature — 1.277; 1.134; 1.300; 1.271 kcal/min
N/A N=20 Effect of Vestibular Stimulation on Fat Consumption and Energy Expenditure as Assessed Using Indirect Calorimetry
Obesity · Metabolic Syndrome
Primary: Change in Fat Consumption (During VeNS) — 50.23; 54.44 % of fat as metabolic substrate
N/A N=38 Caloric Restriction in Treating Patients With Stage 0-I Breast Cancer Undergoing Surgery and Radiation Therapy
Ductal Breast Carcinoma in Situ · Invasive Ductal Breast Carcinoma · Invasive Lobular Breast Carcinoma
Primary: Number of Participants Who Are Adherent to the Diet Restriction — 28 participants
Phase 3 N=164 Calorie Restriction and Changes in Body Composition, Disease, Function, and Quality of Life in Older Adults
Obesity · Diabetes · Hypertension
Primary: Change in Abdominal Fat Mass — -192.6; -21.9; -275 Cubic cm
N/A N=90 Health, Aging and Later-Life Outcomes
Aging
Primary: Number of Participants That Sustained >10% Caloric Restriction — 7; 12 Participants
N/A N=24 Growth Hormone as a Determinant of Weight Regulation
Obesity
Primary: 24 Hour Average Plasma Growth Hormone Concentration — 0.4; 1.2; 4.1 ng/mL
N/A N=20 Essential Amino Acids and Protein Kinetics During Caloric Deprivation
Muscle Protein Synthesis · Whole-body Protein Balance
Primary: Postprandial, Resting Muscle Protein Synthesis Rates — 0.055; 0.061 percent per hour
N/A N=26 Effects of 12 Weeks of Omega 3 Supplementation on Resting Metabolic Rate
Whole Body Energy Metabolism
Primary: Change in Resting Metabolic Rate From Baseline — -0.19; -0.19; 0.67; 1.11 percent change
N/A N=26 Fatty Acid Oxidation Disorders & Body Weight Regulation Grant
Trifunctional Protein Deficiency
Primary: An Outcome of This Study is the Difference in Percent Body Fat (%BF) Between Subjects With a Long-chain Fatty Acid Oxidation Disorder and Normal Controls. — 31.8; 27.2…
N/A N=56 Effect of Energy Density Over 5 Days in Preschool Children
Feeding Behavior
Primary: Differences in Food and Beverage Intake by Energy — 956; 884; 1041 kilocalories — p=< 0.0001
N/A N=6 Effects of Estrogen Deficiency on Energy Expenditure
Obesity
Primary: Brown Adipose Tissue Activity — 3.9; 4.0 Standard uptake value (SUV) — p=0.84
N/A N=82 Fructose Consumption and Metabolic Dysregulation
Central Obesity · Hypertriglyceridemia
Primary: TG Plasma AUC — 1130; 1220 mmol/l*min — p=0.005
N/A N=32 The Influence of Glycemic Control and Obesity on Energy Balance and Metabolic Flexibility in Type 1 Diabetes
Type 1 Diabetes
Primary: Energy Expenditure — 1978.3; 1969.8; 2414.8; 1497.7 Kilocalories — p=0.24