N/A N=19 Robotic Cardiac Surgery Wet Lab Simulation Study
Robotic Cardiac Surgery Simulation
Primary: Time-based Score — 553; 127; 143 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=164 Extracardiac Complications After Cardiac Surgery
Acute Lung Injury · Sepsis · Infections
Primary: Acute Lung Injury After Cardiac Surgery — 20 participants — p=<0.05
Phase 4 N=314 Effects of Microplegia on Transfusion Rates After Cardiac Surgery
Aortic Valve Disease · Mitral Valve Disease
Primary: Intraoperative and Postoperative Transfusions — 2.43; 2.97; 4.42; 3.50 units of blood per participant — p=0.354
Phase 3 N=201 Risk of Oxygen During Cardiac Surgery Trial
Cardiac Surgery
Primary: Intraoperative Systemic Oxidative Damage — 69; 83 pg/ml
Phase 4 N=57 Study of High Dose Vitamin C On Outcome in Cardiac Surgery Patients
Reperfusion Injury
Primary: Mortality — 0; 0 participants
Phase 2 N=51 Measures to Lower the Stress Response in Pediatric Cardiac Surgery
Tetralogy of Fallot (TOF) · Ventricular Septal Defects (VSD) · Atrioventricular Septal Defects (AVSD)
Primary: ACTH and Cytokine Levels — 116.9; 182.7; 135.3; 44.5 pg/mL
N/A N=460 Cerebral Autoregulation Monitoring During Cardiac Surgery
Thoracic Surgery · Cardiopulmonary Bypass
Primary: Composite Neurological Outcome of Clinical Stroke or New Ischemic Brain Lesion on Diffusion Weighted MRI or Neurocognitive Dysfunction 4 to 6 Weeks After Surgery. — 79…
Phase 3 N=2,136 Comparison of Surgical and Medical Treatment for Congestive Heart Failure and Coronary Artery Disease
Cardiovascular Diseases · Coronary Disease · Heart Failure, Congestive
Primary: H01: All Cause Mortality — 244; 218 participants — p=0.12
Early Phase 1 N=40 Telemedicine in Cardiac Surgery: A Pilot Study
Coronary Artery Disease
Primary: Accuracy (FTF Decision on Patient Disposition vs. V-visit Decision on Patient Disposition) — 89 percentage of agreement
N/A N=1,439 Outcomes Study of Hyperinsulinemic Glucose Control in Cardiac Surgery
Cardiac Surgery
Primary: Any Major Morbidity/30-day Mortality — 46; 82 Participants — p=0.0043
N/A N=483 Perioperative Management of Patients With Coronary Stents Undergoing Noncardiac Surgery
Acute Coronary Syndrome · Coronary Stent Occlusion · Surgery
Primary: Major Adverse Cardiac and Cerebrovascular Events (MACCEs) — 63 participants
Phase 1 N=6 Utilization of Confocal Microscopy During Cardiac Surgery
Atrial Septal Defect
Primary: Number of Participants Who Experienced Adverse Events Possibly Related to Study Intervention — 0; 6 Participants
N/A N=180 GDT by Cardiac Index Trending Via a Radial Arterial Line in General Surgery
Reduction of Length of Hospitality Stay, Reduction of Perioperative Complications
Primary: Postoperative Complications — 52; 72 numbers of complications
Phase 3 N=2,203 Outcomes Following Myocardial Revascularization: On and Off Cardiopulmonary Bypass
Ischemic Heart Disease
Primary: Short-term End Point — 61; 77 participants
Phase 4 N=750 The Effect on Blood Loss of Topical and Intravenous Tranexamic Acid in Cardiac Surgery Patients
Blood Loss · Tranexamic Acid · Cardiac Surgery
Primary: Postoperative Blood Loss — 290; 300; 290 ml
N/A N=40 Accuracy of the Dexcom G6 Continuous Glucose Monitoring System Following Cardiac Surgery
Surgery--Complications
Primary: Number of Matching Glucose Measurements (CGM Versus Blood Glucose Measurements) — 817 matched clinical glucose measure
Phase 4 N=91 Graft Patency Outcomes in Patients Undergoing Coronary Artery Bypass Grafting Via Minimally Invasive Coronary Surgery
Arteriosclerosis of Coronary Artery Bypass Graft
Primary: Technical Success (Graft Patency) in a MICS Approach — 100 percentage of grafts
Phase 2 N=11 AZD8601 Study in CABG Patients
Heart Failure
Primary: Number of Subjects With Adverse Events — 7; 4 Participants
Phase 4 N=30 Transepicardial With Transseptal Autologous CD 133+ Bone Marrow Cell Implantation in Patient Following CABG Surgery
Coronary Artery Disease
Primary: Myocardial Defect Perfusion — 15.76; 15.38; 2.08; 3.85 Percentage of Myocardial Perfusion
Phase 4 N=647 Multicenter Infection Surveillance Study Following Open Heart Surgery
Surgery · Pneumonia · Surgical Site Infection
Primary: Hospital Acquired Pneumonia — 8; 18 participants
N/A N=89 Pre-operative Rehabilitation for Reduction of Hospitalization After Coronary Bypass and Valvular Surgery.
Patients Waiting for Coronary Artery Bypass Graft Surgery · Patients Waiting for Aortic Valve Repair or Replacement · Patients Waiting for Mitral Valve Repair or Replacement
Primary: Proportion of Patients With Hospital Length of Stay Greater Than 7 Days. — 20; 16 Participants
N/A N=200 Clinical Evaluation of the CM-1500 in Postoperative Surgery Patients
Blood Loss
Primary: Relative Index Change During PACU Stay — -2.01; -1.32 Relative Index (RI)
N/A N=439 Evaluation Of New Onset Postoperative Atrial Fibrillation
Atrial Fibrillation New Onset
Primary: Primary Safety Endpoint — 3.9; 3.6 percentage of participants
N/A N=722 Balancing Risk: Red Blood Cell Transfusion Strategies In Cardiac Surgery
Anemia
Primary: A Composite of In-hospital Postoperative Morbidity and Mortality — 59; 68 Participants
Phase 3 N=33 Vitamin C for Prophylaxis of Post-operative Atrial Fibrillation in On-pump Cardiac Surgery Procedures
Atrial Fibrillation
Primary: Incidence of Postoperative Atrial Fibrillation — 5; 4; 5 participants
Phase 3 N=882 Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery On Cardiopulmonary Bypass
Coronary Artery Bypass Grafting · Mitral Valve Surgery · Low Cardiac Output Syndrome
Primary: Number of Dual Efficacy Endpoint Events — 56; 48 events
Phase 2 N=29 Confirming The Sitaxsentan Dose In Patients Undergoing Heart Surgery
Cardiac Surgery Subjects · Subjects Undergoing CABG and/or Cardiac Valve Replacement
Primary: Percent Change From 0 Hour in Pulmonary Vascular Resistance (PVR) at 0.5 Hour Post-separation From Cardiopulmonary Bypass (CPB) — -7.75; -10.94; 62.22 percent change…
N/A N=37 The Effect of Tight Glycemic Control on Surgical Site Infection Rates in Patients Undergoing Open Heart Surgery
Diabetes · Hyperglycemia · Surgical Site Infection
Primary: Number of Participants Undergoing Open Heart Surgery With Postoperative Surgical Site Infection — 4; 5; 5 participants — p=0.512
N/A N=200 Cerebral Oximetry and Neurocognitive Functions in Cardiosurgical Patients
Coronary Artery Disease · Postoperative Cognitive Dysfunction · Neurological Impairment
Primary: Difference in Incidence of Cognitive Impairment Between Groups. Change Between Preoperative and Postoperative Cognitive Function Was Assessed by Performing Standardized…
N/A N=100 Delirium and EuroSCORE II in Cardiac Surgery
Delirium
Primary: Number of Participants With Delirium — 5 Participants