N/A N=300 Cervical Preparation Before Dilation and Evacuation
Abortion, Induced
Primary: Operative Time — 6.27; 6.28; 5.53 minutes
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=96 12 Versus 20 mL PCB for D&E Cervical Prep
Pain
Primary: Pain Immediately Following Dilator Insertion — 41; 49 score on a scale
N/A N=41 Paracervical Block for Pain Associated With Laminaria Insertion
Pain
Primary: Pain After Placement of Laminaria (100 mm Visual Analog Scale) — 13; 54 units on a scale (100 mm VAS) — p=0.01
Phase 4 N=70 24-hour Mifepristone and Buccal Versus Mifepristone and Vaginal Misoprostol for Cervical Preparation for D&E
Abortion, Second Trimester
Primary: Procedure Time — 9.5; 9.9 minutes
N/A N=50 Mifepristone Versus Laminaria Insertion for Cervical Preparation Prior to Surgical Abortion at 14-16 Weeks
Abortion
Primary: Time for Completion of Procedure — 8.0; 9.87 Minutes — p=0.05
N/A N=50 Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 Weeks
Abortion, Induced
Primary: Procedure Time — 10.9; 11.8 minutes
N/A N=32 Transcervical Balloon Compared to Osmotic Dilators Prior to Surgical Abortion
Abortion, Second Trimester
Primary: Procedure Time — 22.4; 22.6 minutes
Phase 3 N=50 Mifepristone Versus Osmotic Dilator Insertion for Cervical Preparation Prior to Surgical Abortion at 15-18 Weeks
Cervical Preparation
Primary: Length of Procedure — 14; 13.5 minutes
N/A N=125 Misoprostol Versus Dilapan-S for Cervical Preparation
Cervical Ripening
Primary: Cervical Dilation in Women Following Exposure to Either Ripening Agent — 32.1; 33.9 mm
Phase 2 N=18 CerviPrep for Applying Topical Gemcitabine to the Cervix in Treating Patients With Primary Endometrial, Cervical, or Ovarian Epithelial Cancer
Cervical Cancer · Endometrial Cancer · Ovarian Cancer
Primary: Number of Patients With Measurable Concentration of Gemcitabine in Uterine Vein (dFdC) — 5 Participants
Phase 4 N=100 Same-Day Mifepristone-Misoprostol Compared to Misoprostol Only for Surgical Abortion Cervical Preparation
Induced Abortion
Primary: Initial Cervical Dilation — 11.7; 10.9 mm
Phase 3 N=72 Self-administered Lidocaine Gel for Pain-control During Cervical Preparation for Dilation and Evacuation
Pain Management, Cervical Preparation
Primary: Pain Perceived at the Time of Laminaria or Osmotic Dilator Insertion — 48.4; 56.3 units on a scale
N/A N=144 Balloon Catheter for Cervical Ripening
Cervical Dilation
Primary: Duration — 16.2; 16.9 hours — p=0.814
N/A N=180 Laminaria Compared to Dilapan-S for Cervical Preparation Before Dilation and Evacuation at 18-24 Weeks of Gestation
Second Trimester Abortion
Primary: D&E Procedure Time — 7.35; 7.55 minutes
Phase 2 N=80 Paracervical Block During Office Hysteroscopy
Paracervical Block
Primary: Assessment of Pain on a 10-point Visual Analog Pain Scale During the Procedure. — 4.15; 3.38 Score on a scale — p=<.001
Phase 2 N=51 Efficacy and Safety Study of the Misoprostol Vaginal Priming Insert (MVPI) Prior to Hysteroscopy
Cervical Priming
Primary: Change in Diameter of the Internal Cervical os From Baseline (Pre-treatment) to Just Prior to the Hysteroscopy Procedure (Post-treatment). — 2.2; 2.3; 1.5 mm
N/A N=72 Dilapan Versus Laminaria
Cervical Preparation
Primary: Procedure Time — 5.9; 8.1 minutes
Phase 2 N=133 Treatment of High-Grade Pre-Neoplastic Cervical Lesions (CIN 2/3)
Cervical Intraepithelial Neoplasia · Cervical Dysplasia
Primary: Incidence of Objective Response — 32; 36; 30; 0 Participants — p=0.043
Phase 3 N=465 PREGNANT Short Cervix Trial
Preterm Delivery · Short Cervix · Short Uterine Cervical Length
Primary: Number of Participants With Birth <=32 6/7 Weeks Gestation. — 36; 21 participants — p=0.020
N/A N=89 Paracervical Versus Intracervical Lidocaine
Abortion, Induced · Pain
Primary: Pain Score, as Assessed Using a 10 cm Linear Visual Analog Scale (VAS) — 4.25; 3.97 units on a scale
N/A N=102 Comparison of Pre-Induction Cervical Ripening
Failed Labour
Primary: Vaginal Delivery — 20; 21; 20 participants
N/A N=80 Modifying Cervical Bishop Scoring System
Failed Induction of Labor
Primary: Area Under Receiver Operating Characteristic Curve (ROC) for Modified Bishop Score — 0.916 probability — p=0.000
N/A N=230 Cervical Ripening in Premature Rupture of Membranes
Pregnancy · Premature Rupture of Membranes · Preterm Premature Rupture of Membranes
Primary: Rate of Cesarean Section — 27; 26; 89; 86 participants — p=0.99
N/A N=130 An Innovative Treatment for Cervical Pre Cancer
Cervical Intraepithelial Neoplasia
Primary: Mean Depth of Necrosis Achieved With the LMIC-adapted CryoPen and the Thermocoagulator Compared to Mean Depth of Necrosis Achieved With CO2-based Cryotherapy — 6.0; 5.6…
Phase 3 N=114 Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage.o
Abortion, Spontaneous · Abortion in First Trimester · Pain Uterus
Primary: Pain With Cervical Dilation — 52; 45 units on a scale
Phase 4 N=236 Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness Trial
Obesity · Labor Induction · Cesarean Delivery
Primary: Number of Participants With a Need for Cesarean Delivery — 51; 53 Participants
N/A N=100 Foley Catheter Compared to the Foley Catheter Alone for Cervical Ripening
Cervical Ripening · Induction of Labor
Primary: The Median Times From Placement of Foley Catheter to Vaginal Delivery — 21.2; 31.3; 17.1; 14.8 hours
Phase 1 N=30 Intravaginal Artesunate for the Treatment of HPV+ High Grade Cervical Intraepithelial Neoplasia (CIN2/3)
Cervical Intraepithelial Neoplasia Grade 2/3 · High-risk HPV (Any Strain)
Primary: Number of Participants With Serious Adverse Events — 0; 0; 0; 0 Participants
N/A N=20 Cervix Monitor for Elasticity and Length Measurements
Preterm Birth
Primary: Cervix Elasticity — 54; 19.7 kPa
N/A N=50 Cervical Ripening for Induction of Labor: Misoprostol Versus Oxytocin in Conjunction With Foley Balloon
Induction of Labor
Primary: Rate of Induction To Delivery — 732.19; 944.35 minutes — p=0.037