Phase 4 N=23 Serum and Tissue Cefazolin Concentrations in Patients Undergoing Cesarean Delivery
Cesarean Delivery · Wound Infection · Obesity
Primary: Cefazolin Levels — 18.36; 40.11; 21.73; 34.89 mcg/mL — p=<0.01
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=380 The Role of Antimicrobial Foam Dressing in Prevention of Cesarean Section Wound Complications
Cesarean Section; Complications, Wound, Dehiscence
Primary: Number of Participants With Wound Disruption and/or Infection — 5; 9 Participants
N/A N=2,013 Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean Infection
Endometritis · Wound Infection · Abscess
Primary: Participants With Endometritis and/or Wound Infection and/or Other Post-cesarean Infections (Occurring Within 6 Weeks of Delivery) — 119; 62 Participants
N/A N=400 Timing of Antibiotic Prophylaxis for Cesarean Deliveries
Infection
Primary: Endometritis and Wound Infection — 6; 4 patients infected
N/A N=1,064 Effect of Prophylactic Negative Pressure Versus Silver Impregnated Silicone Bandage on C-Section Infection Rates
D001458 · D011247
Primary: Infection Rate — 17; 18; 5; 5 Participants
N/A N=92 The Use of the Prevena™ Incision Management System on Post-Surgical Cesarean Section Incisions
Post-operative Complications · Surgical Site Infection · Surgical Wound Infection
Primary: Incidence of Postoperative Surgical Site Occurrences (SSOs) up to Day 42 (+/- 10 Days) Post Cesarean Section Surgery. — 7; 2 participants
N/A N=168 Short Term Comparison of Two Different Techniques of Uterine Cesarean Incision Closure
Cesarean Section Complications
Primary: Cesarean Scar Defect in the Uterine Incisional Line — 12; 39 participants — p=0.0001
N/A N=168 Long Term Comparison of Two Different Techniques of Uterine Cesarean Incision Closure
Cesarean Section; Complications · Placenta Previa · Placenta Accreta
Primary: Placenta Previa — 18; 17; 0; 3 Participants
N/A N=657 Prospective Study on Cesarean Wound Outcomes
Surgical Site Infection · Cosmetic Appearance of Cesarean Scar · Post Operative Pain
Primary: Percentage of Patients Who Develop a Surgical Site Infection — 14; 15 Participants — p=<0.05
N/A N=932 Chlorhexidine-Alcohol Versus Povidone-Iodine for Cesarean Antisepsis
Surgical Site Infection
Primary: Number of Patients With Surgical Site Infection — 29; 33 Participants — p=0.38
N/A N=1,404 Comparison of Surgical Skin Preps During Cesarean Deliveries
Surgical Site Infection Following Cesarean Delivery
Primary: Cesarean Surgical Site Infection — 18; 21; 21; 15 Participants
N/A N=79 Improving Cesarean Section Experience Through Hypnotherapy
Cesarean Section · Pain · Anxiety
Primary: Wellbeing Measured Using a Comfort Scale — 6.7; 8.0 units on a scale
Phase 4 N=753 Seprafilm® Adhesion Barrier and Cesarean Delivery
Adhesions · Cesarean Section · Delivery, Obstetric
Primary: Incidence of Adhesions — 75.6; 75.9 percentage of patients with adhesions
N/A N=1,356 STRIPES Study: Study To Reduce Infection Post cEsarean Section
Chlorhexidine Gluconate Cloths · Infection; Cesarean Section · Infectious Morbidity
Primary: Number of Participants With Incisional SSI — 17; 24 Participants
N/A N=69 High Pain Intervention in Cesarean Sections
Other Chronic Postoperative Pain
Primary: Severity of Acute Pain — 46; 31 mm — p=0.05
N/A N=120 Prophylactic Incisional Care in Obese Women at Cesarean
Wound Infections
Primary: Number of Participants With Composite Surgical Site Infection (SSI) or Other Wound Complication. — 5; 3 Participants — p=0.72
Phase 4 N=30 Increased Cefazolin During Cesarean Delivery in Obese Population
Obesity · Obesity, Morbid · Pregnancy
Primary: Achievement of Minimal Inhibitory Concentrations Within Adipose and Serum Sampled at Time of Cesarean Delivery — 22.4; 9.6 mg/g
N/A N=110 Negative Pressure Wound Therapy After Cesarean Delivery
Major Puerperal Infection, Postpartum · Wound Complications · Wound Seroma
Primary: Wound Complication Rate — 3; 1; 3; 6 participants
N/A N=1,147 The Skin Prep Study
Surgical Site Infections
Primary: Number of Participants With Surgical Site Infection — 23; 42 Participants — p=0.02
N/A N=541 Cesarean Section Via Enhanced Recovery
Cesarean Section
Primary: Opioid Consumption — 60.34; 104.33 oral morphine equivalents (mg) — p=< 0.001
N/A N=553 Effect of Intra-operative Glove-changing During Cesarean Section on Post-op Complications: A Randomized Controlled Trial
Wound Complications
Primary: Composite Wound Complication — 34; 15 Participants
N/A N=301 Self-Retaining Retractor in Obese Patients Undergoing Cesarean Section
Pregnancy · Obese
Primary: Wound Infection or Disruption — 38; 37 participants
N/A N=1,274 Timing of Planned Caesarean Section and Morbidity of the Newborn
Respiratory Disorders · Intensive Care, Neonatal
Primary: Neonatal Admission After Elective Caesarean Section — 88; 76 participants — p=0.31
N/A N=746 Cesarean Trial of Staples vs. Sutures
Cesarean Section · Wound Complications · Patient Satisfaction
Primary: Number of Participants With Wound Complications — 18; 40; 9; 14 Participants
Phase 4 N=550 Subcuticular Suture for Cesarean Skin Incision Closure
Complications; Cesarean Section · Surgical Wound Infection
Primary: Number of Participants With Wound Complications (Surgical Site Infection (SSI), Hematoma, Separation, Seroma, Etc) — 23; 37; 16; 25 Participants — p=0.04
N/A N=136 PROphylactic Wound VACuum Therapy to Decrease Rates of Cesarean Section in the Obese Population
Wound Complication
Primary: Number of Participants With Wound Complications — 3; 4 Participants
Early Phase 1 N=186 Antibiotic Prophylaxis to Prevent Obesity-Related Induction Complications in Nulliparae at Term
Obesity · Induction of Labor Affected Fetus / Newborn
Primary: Number of Participants With Cesarean Delivery — 27; 37 Participants
N/A N=40 Opportunistic Salpingectomy for Permanent Sterilization at the Time of Cesarean Delivery
Contraception
Primary: Mean Difference Between Pre and Postoperative Hemoglobin (g/dl) — 1.4; 1.8 g/dL — p=0.08
N/A N=702 Prospective, Randomized, Parallel-arm Clinical Trial of CleanCision or Alexis O in Elective Colorectal Surgery
Colorectal Surgery
Primary: Surgical Site Infection (SSI) Rate — 16; 14; 6; 1 Participants
N/A N=300 Evaluation of Wound Infection Rates and Cosmetic Results of Different Suture Materials in Cesarean Skin Incision
Cesarean Section; Infection · Scar
Primary: Evaluation of the Difference Between the Groups in the Number of Patients With Wound Infection at the End of the 10th Postoperative Day — 80; 90; 93; 12 Participants