Clinical Trial Search

Primary: Family Wellbeing: Depression — 14.19; 10.82; 9.76; 11.67 score on a scale — p=0.026

Primary: Percentage of Sessions Completed — 100 percentage of intervention sessions

Primary: Veteran Engagement in VA Mental Health Services — 4; 4 participants — p=0.927

Primary: Abstinence — 55.0; 49.5 days

Primary: Multnomah Community Ability Scale (MCAS) — 67.78; 74.63; 70.00; 74.38 units on a scale

Primary: Longest Duration of Abstinence From Cocaine — 4.14; 6.64; 6.93 weeks — p=.01

Primary: Abstinence Rate (During the Preceding 90 Days) at 12 Months Follow-up Point as Assessed by the Form-90 — 40; 38; 47; 51 participants

Primary: Form-90 Timeline Followback Interview — .78; .64 proportion of days abstinent

Primary: Alcohol Abstinence — 2.9; 2.6 Samples — p=0.66

Primary: Community Reinforcement And Family Training (CRAFT) Procedure Fidelity — 44.00; 52.75; 57.25 Score on a scale — p=0.0008

Primary: Number of Participants Showing Resurgence as Predicted by the Quantitative Model -- Highest Response Rate — 1; 5 Participants

Primary: Number of Teens Using Any Alcohol During Past 6 Months — 16; 20; 38; 14 Participants — p=<0.01

Primary: Change From Baseline in the Eyberg Child Behavior Inventory (ECBI) Score at Different Time Points (Baseline up to 18 Weeks) — -7; -22; -2; -5 units on a scale

Primary: Binge Eating Frequency Assessed by the Eating Disorder Examination — 25.10; 25.27; 9.19; 13.07 Binge eating episodes

Primary: Acceptance of Intervention-Number of Participants Who Dropped Out of Treatment — 4; 3 Participants

Primary: Change in Stop Signal Reaction Time — -8.62 ms — p=.003

Primary: Child Welfare Services Removal From Birth Parent Home — 12; 19 Participants — p=.159

Primary: DPICS-IV Observed Parenting Skills (During Child-Led Play) — 2.32; 2.63; 2.86; 2.11 number of behaviors

Primary: Child Welfare Outcomes: CWS Removal From Birth Parent Home — 7; 16 participants — p==.043

Primary: Average Z-score From Participant Self Report on Domains in the Clinical Scale of the Treatment Outcome Package (TOP-CS) at Study Intervention Endpoint — 0.42; 0.63 Z-score

Primary: Average Depression Symptom Scores Over 27 Weeks on the Adolescent Longitudinal Interval Follow-up Evaluation — 3.39; 3.09 score on a scale

Primary: Main Study, Adolescent Drug Use — 3; 3 days of drug use 28 days prior baseline — p=.27

Primary: Percentage of Participants Fully-Adherent to Buprenorphine — 6; 3 Participants

Primary: Depressive Cognitions Scale — 6.46; 6.97; 6.32; 7.28 Score on a Scale

Primary: Cocaine Use as Assessed by Proportion of Visits (Excluding Excused Absences) With Cocaine-negative Urine Drug Screen — 0.31; 0.24 proportion of visits

Primary: Change From Baseline in Communication During Structured Lab Observation (SLO) at 12 Weeks — 45.7; 40.8; 64.5; 51.4 Utterances — p=0.42

Primary: Number of CR Sessions Completed Within 6 Months in Patients Randomized to HYCR vs. Patients Randomized to Traditional CBCR (Usual Care). — 28.7; 27.6 Number of cardiac…

Primary: Number of Participants With Positive Urine Drug Screens at 5 Months Post-baseline — 18; 13 participants

Primary: Biochemically Measured Change in Alcohol Abstinence. — 347; 615; 209 Number of negative BAC samples by phase.

Primary: TOPSE: Group Mean Change at 6 Weeks and 4 Months on the Tool of Parenting Self-Efficacy — 8.77; 7.50; 8.70; 7.65 score on a scale — p=0.014