N/A N=21 Assessment of Contact Lens Wettability Using Wavefront Aberrometry
Visual Acuity
Primary: Higher Order Root Mean Square (HO RMS) - Near Target in Downgaze With Natural Blinking — 0.159; 0.142 microns
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=22 Evaluation of Silicone Hydrogel Lens Wettability With Marketed Lens Care Solutions
Contact Lens Wear
Primary: Ex Vivo Contact Angle — 104.8; 104.9; 103.3 degrees
N/A N=66 Effect of FID 114675A on Lens Wettability
Contact Lens Wettability
Primary: Lens Wettability — 95.5; 97.0 percentage of lenses
N/A N=21 In-vivo Wettability Grading and Assessment Study
Myopia
Primary: On-eye Wettability — 1.33; 2.11; 1.70; 2.07 units on a scale
N/A N=32 Objective Testing of Tear Film Stability
Contact Lens Solutions
Primary: Objective, In-vivo Soft Contact Lens Wettability Index — -1.82; -1.98 wettability index
N/A N=70 Comparative In-Vivo Wetting Characteristics of Silicone Hydrogel Materials With Selected Lens Care Systems
Myopia · Astigmatism · Refractive Error
Primary: Mean Ex-Vivo Total Lipid Uptake Per Lens — 7.198; 35.879 micrograms
Phase 3 N=246 Safety and Acceptability of Using a Rewetting Drop With Contact Lens Wear
Ametropia
Primary: Best Corrected Visual Acuity — 0.65; 1.33; 98.06; 98.67 Percentage of Participants
N/A N=40 Single Site Study of the Wettability of Contact Lenses With an Investigational Multi-Purpose Disinfecting Solution vs. a Marketed Multi-Purpose Solution
Contact Lens Care
Primary: Mean Ex-Vivo Wetting Angle — 52.1; 59.6 Degrees
N/A N=61 Evaluation of Comfilcon A and Senofilcon A Lenses
Myopia
Primary: Subjective Responses for Comfort Rated on a 0-100 Visual Scale. — 86; 87; 89; 91 units on a scale
N/A N=28 Subjective Comparison of Pre-Lens Tear Film Stability With Daily Disposable Contact Lenses
Myopia · Hyperopia · Refractive Error
Primary: Pre-Lens Non-Invasive Keratograph Break Up Time (PL NIK-BUT) at 8 Hours — 5.28; 3.46; 4.93 seconds
N/A N=60 A Comparison of Two Daily Disposable Contact Lenses
Myopia
Primary: Visual Acuity — -0.10; -0.10; 0.17; 0.18 logMAR scale
Phase 4 N=20 The Impact of Contact Lens Coefficient of Friction (CoF) on the Development of Lid Wiper Epitheliopathy (LWE)
Lid Wiper Epitheliopathy
Primary: Lid Wiper Epitheliopathy — 0.63; 0.25 score on a scale
N/A N=24 Lubricity Post-Wear - Competitive Lenses Pilot
Refractive Error
Primary: Average Coefficient of Friction of Worn Lenses at 16 Hours — 0.0602; 0.0576; 0.0578 unitless
N/A N=60 Dailies Total 1 Sphere Contact Lenses
Dry Eye · Contact Lens Complication
Primary: Visual Analog Scale (VAS) Contact Lenses Comfort Scores — 44 Score on a scale — p=<0.001
N/A N=30 Evaluation of Wear Experience With a Water Surface Daily Disposable Contact Lens
Contact Lens
Primary: Subjective Assessment of Overall Comfort With Verofilcon A Daily Disposable Lenses for Astigmatism — 91 units on a scale
N/A N=59 Daily Wear Comparison of Enhanced and Non-Enhanced Silicone Hydrogel Lenses
Myopia
Primary: Overall Vision — 8.7; 8.7 Units on a Scale
N/A N=248 A Comparison of Daily Disposable Contact Lenses.
Myopia
Primary: Overall Comfort — 3.903; 3.349 Units on a scale
N/A N=15 DAILIES TOTAL1® Lubricity Post Wear
Refractive Error
Primary: Average Coefficient of Friction (CF) at 16 Hours Compared to Unworn — 0.0394; 0.0396 unitless
N/A N=166 Study to Evaluate a Contact Lens Lubricating and Rewetting Drop
Dry Eye
Primary: Percentage of Eyes With Graded Slit Lamp Findings Greater Than Grade 2. — 1; 0 eyes
N/A N=21 Tangible Hydra-PEG: A Promising Solution for Scleral Lens Wearers With Dry Eye
Dry Eye · Dry Eye Syndromes
Primary: Ocular Surface Tear Breakup Time — 3.81; 2.91 seconds — p=<0.01
Phase 4 N=73 Direct Application of Systane Complete to Contact Lenses
Dry Eye · Contact Lens Complication
Primary: Difference in Ocular Surface Damage as Measured by the Brien Holden Vision Institute (BHVI Grading Scale) at Two Weeks — 0.44; 1.08; 0.83 Score on a Scale — p=0.30
N/A N=127 Senofilcon A Investigational Manufacturing Process
Visual Acuity · Comfort · Overall Vision
Primary: Subjective Overall Comfort (Using CLUE ) — 63.3; 65.0 units on a scale
N/A N=39 Pre-Lens Tear Film Performance of Silicone Hydrogel Daily Disposable Contact Lenses
Myopia
Primary: Pre-Lens Non-Invasive Tear Break-Up Time (PL-NITBUT) — 13.56; 12.0; 11.86 seconds
N/A N=60 Clinical Performance of Hydrogel vs. Silicone Hydrogel Contact Lenses
Myopia
Primary: Participant's Subjective Rating for Lens Handling - Enfilcon A / Omafilcon A — 97; 84 units on a scale
N/A N=33 Clinical Biocompatibility Evaluation of Contact Lens Coatings
Refractive Errors · Ametropia
Primary: Average Percent Area of Solution-related Corneal Staining — 7.01; 12.82; 13.54; 7.58 percentage of area
N/A N=26 Dehydration of Omafilcon A Contact Lenses Versus Delefilcon A Contact Lenses
Myopia
Primary: Absolute Change in Water Content (Mean) of Omafilcon A and Delefilcon A — 1.59; 3.82 absolute WC change
N/A N=9 Daily Disposable Contact Lens Tear Film Study
Myopia
Primary: Number of Participants With Corrected Visual Acuity of 0.0 or Better — 9; 9; 9; 9 participants
N/A N=120 Clinical Comfort Evaluation of Two Marketed Spherical Contact Lenses
Astigmatism
Primary: Comfort at Insertion — 8.7; 8.5 units on a scale
N/A N=35 Evaluation of Tangible Boost Replenishing System
Contact Lens Solution
Primary: Number of Patients With Adverse Event Reports or Discontinuations — 4; 2; 4 Participants
N/A N=40 Fitting Evaluation of Hydrogel and Silicone Hydrogel Spherical Contact Lenses
Myopia
Primary: Visual Acuity Using logMAR — -0.14; -0.13; -0.13; -0.14 logMAR