N/A N=34 Positive Airway Pressure Program
Sleep Apnea, Obstructive
Primary: Participant Providing Feedback — 26 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=1,105 Apnea Positive Pressure Long-Term Efficacy Study
Lung Diseases · Sleep Apnea Syndromes · Sleep
Primary: Effect of CPAP on Neurocognitive Function: E/F Function- SWMT-OMD — 0.035; -0.074; 0.072; 0.018 score on a scale — p=0.0074
N/A N=164 Positive Pressure Treatment of Obstructive Sleep Apnea
Obstructive Sleep Apnea
Primary: Apnea-Hypopnea Index — 6.09; 3.54; 3.24; 1.26 events/hour — p=0.3
N/A N=194 Effect of Positive Airway Pressure on Reducing Airway Reactivity in Patients With Asthma (CPAP)
Asthma
Primary: Methacholine Reactivity — 2.13; 1.48; 1.44; 1.60 mg/mL — p=0.51
N/A N=59 Modulation Of Airway Reactivity With Chronic Mechanical Strain
Asthma
Primary: Change in Airway Reactivity From Baseline (Visit 1) and 4 Weeks (Visit 2) — 3.0; 3.2; 5.3; 4.3 mg/mL
N/A N=32 Auto Continuous Positive Airway Pressure (CPAP) Based Energy Spectrum Analysis of Flow for Treatment of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Sleep Apnea, Obstructive
Primary: Apnea Hypopnea Index (AHI) — 2.4 events per hour
N/A N=25 Servo-Ventilation In-lab PSG Evaluation
Sleep Apnea Syndromes
Primary: Average Apnea Hypopnea Index Among Different Polysomnography Devices. — 18.4; 25.4; 24.1; 19.2 events per hour
N/A N=21 Auto-PAP for Pulmonary Hypertension Treatment in Decompensated HF Patients With Sleep Apnea.
Sleep Apnea, Obstructive · Hypertension, Pulmonary · Heart Failure
Primary: Pulmonary Artery Systolic Pressure. — 58.6; 62.7; 42.8; 57.5 mmHg
N/A N=111 Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal Endoscopy
Hypoxia · Endoscopy · Anesthesia Morbidity
Primary: Hypoxia Rate as Assessed by Number of Participants With at Least One Hypoxic Event — 3; 16 Participants
Phase 2 N=12 Sleep Apnea Treatment With Expiratory Resistance(Provent™)
Sleep Apnea, Obstructive
Primary: Change in AHI — 45; -15.8 events/h
N/A N=270 Self-Management of Continuous Positive Airway Pressure Settings
Obstructive Sleep Apnea
Primary: Treatment Adherence — 2.1; 2.2 Hours per night
N/A N=40 Prophylactic nCPAP Following Bowel Surgery (Bio-REB File 11-27)
Postoperative Pulmonary Atelectasis · Surgery
Primary: Alveolar - Arterial Gradient — 70.6; 134 torr
N/A N=169 CPAP (Continuous Positive Airway Pressure) Study Educational Materials and Usage Feedback to Promote CPAP Adherence
Adherence
Primary: Nightly Adherence — 4.83; 5.82; 4.82; 4.60 hours
N/A N=281 Continuous Positive Airway Pressure to Improve Milder Obstructive Sleep Apnea
Lung Diseases · Sleep Apnea Syndromes · Hypertension
Primary: Change in the Score of the Functional Outcomes of Sleep Questionnaire at Baseline and Week 8 Treatment — 0.98; -0.14 scores on a scale
N/A N=156 Continuous Positive Airway Pressure (PAP) Titration and Treatment Versus Auto-adjusting PAP Treatment for Sleep Apnea
Obstructive Sleep Apnea
Primary: Positive Airway Pressure Adherence (Nightly Use of Treatment) — 3.99; 4.45 hours — p== 0.27
N/A N=150 TPAP for Comfort in OSA
Obstructive Sleep Apnea
Primary: CPAP v TPAP Patient Preference at 9 cmH2O Baseline Pressure, TPAP Drop 2+2 cmH2O — 69.3 percentage of total participants
N/A N=111 Effects of Continuous Positive Airway Pressure (CPAP) on Glucose Metabolism
Obstructive Sleep Apnea · Sleep Apnea · Sleep-disordered Breathing
Primary: Insulin Sensitivity (SI) — 1.95; 2.22 [mU/L]^-1 x [min]^-1
N/A N=78 CPAP vs ASV for Insomnia
Insomnia · Sleep-Disordered Breathing
Primary: Insomnia Severity Index — 9.29; 13.21 units on a scale
N/A N=33 Revised Algorithm for Next Generation DeVilbiss Healthcare AutoAdjust Continuous Positive Airway Pressure (CPAP)
Obstructive Sleep Apnea
Primary: % Agreement Between Reviewer and Machine Pressure Settings During Sleep Study — 92.2 percentage of agreement
N/A N=114 Non-invasive Ventilation Versus Continuous Positive Airway Pressure in Cardiogenic Pulmonary Edema
Cardiogenic Pulmonary Oedema
Primary: Need for an Endotracheal Intubation Within Seven Days After Onset of Cardiopulmonary Edema at the Intensive Care Unit — 5; 5 Participants — p=1.000
N/A N=241 Automated Graduated CPAP (AGPAP) for Improved Adherence in Newly Diagnosed Obstructive Sleep Apnea (OSA) Patients
Obstructive Sleep Apnea
Primary: CPAP Adherence — 3.6; 4.0 hours per night
N/A N=50 Duration of Continuous Positive Airway Pressure and Pulmonary Function Testing in Preterm Infants
Respiratory Distress Syndrome · Bronchopulmonary Dysplasia
Primary: Changes in the Measurements of Functional Residual Capacity (FRC) in Randomized Premature Infants — 12.6; 6.4; 27.2; 17.1 mL — p=<0.05
N/A N=36 Evaluation of an Algorithm to Detect Sleep and Wake in Continuous Positive Airway Pressure (CPAP)
Sleep Apnea, Obstructive
Primary: Sleep/Wake Algorithm — 62 accuracy (%)
N/A N=115 Comparison of Breathing Event Detection by a Continuous Positive Airway Pressure Device to Clinical Polysomnography
Sleep Apnea
Primary: Apnea-hypopnea Indices (AHI) as Determined by Polysomnography (PSG) vs Automatic Event Detection (AED ) Algorithm — 5.6; 5.8; 2.4; 3.2 events per hour — p=0.007
N/A N=49 Evaluation of Treatment Efficacy and Comfort of a Modified Positive Airway Pressure Device to Treat Obstructive Sleep Apnea.
Obstructive Sleep Apnea (OSA)
Primary: PAP Treatment Efficacy — 4.2; 4.0 Events per hour
N/A N=193 Targeted CPAP Therapy for Obstructive Sleep Apnea in Pregnancy
Obstructive Sleep Apnea
Primary: Number of Participants With Adverse Pregnancy Outcomes — 45; 39 Participants — p=<0.05
N/A N=21 Positive Airway Pressure for the Treatment of Asthma
Asthma · Sleep Apnea
Primary: Asthma Control Test — 19.3; 19.8; 19.1; 19.6 units on a scale — p=0.8
N/A N=21 Adjustment of Mask Pressure, for Bilevel Positive Airways Pressure Therapy, by Automated Algorithm
Respiratory Insufficiency · Sleep Disordered Breathing
Primary: Index of Apneoas Plus Hypopnoeas Per Hour of Sleep (AHI) — 1.3; 1.7 Events per hour of sleep
N/A N=20 High Intensity Non-Invasive Positive Pressure Ventilation (HINPPV)
Chronic Obstructive Pulmonary Disease (COPD)
Primary: Daytime Partial Pressure of Carbon Dioxide in Arterial Blood (PaCO2) — 53; 50 mmHg — p=0.01
N/A N=124 Study of Positive Airway Pressure in Preeclampsia to Reduce Blood Pressure
Preeclampsia · Hypertension
Primary: Nocturnal Blood Pressure — 128.2; 124.7; 70.6; 68.8 mmHg — p=0.45