N/A N=146 Arthroscopy in the Treatment of Degenerative Medial Meniscus Tear
Osteoarthritis, Knee
Primary: The Lysholm Knee Score — 82.2; 83.4 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=351 Comparing Surgery Versus Standard Physical Therapy in Treating People With a Meniscal Tear and Osteoarthritis
Osteoarthritis
Primary: WOMAC Functional Status - Difference From Baseline — 20.9; 18.5 Score — p=0.26
N/A N=140 Surgical or Exercise Therapy on Patients With Degenerative Meniscus Tears
Degenerative Meniscal Tear
Primary: KOOS4 - Change From Baseline — 24.4; 25.3 units on a scale — p=<0.05
N/A N=16 Prospective Trial of Arthroscopic Meniscectomy for Degenerative Meniscus Tears
Meniscus Tear
Primary: WOMET Score — 57.5; 99.4; 37.0; 63.9 units on a scale
Phase 2 N=20 Autologous, Micro-fragmented Adipose Tissue for Meniscal Tears
Tibial Meniscus Injuries · Osteoarthritis, Knee
Primary: Change in Numerical Pain Scale — -3.2 units on a scale
N/A N=30 Study of Suture Repair of Torn Meniscus in the Knee
Meniscal Tear · Meniscus Tear
Primary: Freedom From Re-operation of the Index Meniscus Repair Site (Incidence of Subjects Requiring Re-operation) — 26; 1; 23; 2 Participants
Phase 2 N=102 Study of TG-C in Patients With Grade 3 Degenerative Joint Disease of the Knee
Osteoarthritis, Knee
Primary: Change From Baseline in the International Knee Documentation Committee (IKDC) Subjective Knee Evaluation Score at 1 Year — 23.3; 9.9 scores on a scale — p=<0.01
N/A N=27 Muscle Weakness and Post-traumatic Knee OA
Meniscectomy
Primary: Change in International Knee Documentation Committee (IKDC) Subjective Knee Form Score — 22.2; 20.6 units on a scale
Phase 3 N=144 Superiority of MACI® Versus Microfracture Treatment in Patients With Symptomatic Articular Cartilage Defects in the Knee
Articular Cartilage Defect
Primary: Change From Baseline to Week 104 for the Participant's Knee Injury and Osteoarthritis Outcome Score (KOOS) Pain and Function (Sports and Recreational Activities) Scores…
Phase 1 N=12 Safety Study of TissueGene-C in Degenerative Joint Disease of the Knee
Osteoarthritis, Knee
Primary: Summary of Adverse Events — 2; 2; 3; 2 Adverse events
N/A N=101 Role of Bone in Knee Osteoarthritis (OA)
Osteoarthritis, Knee
Primary: Number of Participants With Viable Specimens for Genetic Analysis — 14 participants
Phase 3 N=40 The Effect of Micro Fragmented Adipose Tissue (MFAT) on Knee Osteoarthritis
Osteoarthritis, Knee · Knee Pain
Primary: Change in Knee Injury and Osteoarthritis Outcomes Score (KOOS) Score - Pain — 64.4; 62.5; 63.9; 13.2 score on a scale — p=0.594
N/A N=10 A Biologic Joint Replacement Strategy to Treat Patients With Severe Knee Trauma and Post-Traumatic Knee Osteoarthritis
Post-traumatic Osteoarthritis
Primary: Visual Analogue Scale Pain Score — 2.3 units on a scale
N/A N=50 Osteoarthritis Structural Changes Assessed by Magnetic Resonance Imaging and Neuropathic Pain in Knee Osteoarthritis
Neuropathic Pain · Knee Osteoarthritis
Primary: Osteoarthritis Structural Changes Assessed by Quantitative Magnetic Resonance Imaging With and Without Neuropathic Pain — 14; 7; 5; 1 participants
N/A N=18 High-Purity Type I Collagen Augmentation in Meniscal Repair
Meniscus Tear · Knee Meniscus Injury · Meniscal Repair
Primary: Safety of High-Purity Type I Collagen Augmentation — 0; 0; 0; 0 Participants
Phase 3 N=380 Effect of Diacerein vs Celecoxib on Symptoms and Structural Changes in Symptomatic Knee Osteoarthritis
Osteoarthritis · Osteoarthritis, Knee
Primary: Change Form Baseline in WOMAC A Pain Subscale — -11.14; -11.82 cm — p=<0.025
Phase 3 N=118 RCT of ChondroCelect® (in an ACI Procedure) vs Microfracture in the Repair of Cartilage Defects of the Knee
Articular Cartilage Lesion of the Femoral Condyle
Primary: Histomorphometry Safranin-O + Anti-Collagen II Antibody Staining — 1.01; 0.75 Ratio — p=0.003
Phase 2 N=12 Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells
Osteoarthritis, Knee · Knee Degenerative Disease · Knee Osteoarthritis
Primary: Feasibility and Safety of the Implementation of MSV in the Treatment of Osteoarthritis of the Knee. — 46.9; 25.1; 24.8; 15.4 units on a scale
N/A N=9 Clinical Application of BioCleanse Meniscus
Tear of Meniscus of Knee
Primary: Knee Injury and Osteoarthritis Outcome Score (KOOS) — 70.1 units on a scale — p=0.06
N/A N=121 MRI of Infrapatellar Fat Pad in Osteoarthritis
Osteoarthritis
Primary: Infrapatellar Fat Pad Volume in MRI — 25154.96; 29202.39 mm^3
N/A N=50 Comparison of SVF Injection With and Without Microfracture in Moderate Knee Osteoarthritis
Knee Osteoarthritis (Knee OA)
Primary: Change in WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) — 49.52; 50.60; 34.16; 49.96 Score
N/A N=80 Knee Bracing for People With Patellofemoral Osteoarthritis
Knee Osteoarthritis
Primary: Change in Pain on the VIsual Analog Scale (VAS) — -.068 change in units on a scale from baseline
Phase 2 N=395 Efficacy and Safety of PG-530742 in the Treatment of Mild to Moderate Knee Osteoarthritis
Osteoarthritis, Knee
Primary: Change in Minimum Joint Space Width in the Medial Compartment of the Tibiofemoral Joint of the Signal Knee After 1 Year of Treatment — -0.1361; -0.0442; -0.2261; -0.2000…
Phase 2 N=35 IMPACT: Safety and Feasibility of a Single-stage Procedure for Focal Cartilage Lesions of the Knee.
Foreign-Body Reaction · Inflammation · Effusion (L) Knee
Primary: Safety: Adverse Events — 0 participants
N/A N=99 Time-dependent Improvement of Functional Outcome Following Oxford Medial Unicondylar Knee Replacement
Osteoarthritis
Primary: Knee Injury and Osteoarthritis Outcome Score — 85.5; 88.2 units on a scale
N/A N=23 Skeletal Muscle Atrophy and Dysfunction Following Total Knee Arthroplasty
Knee Osteoarthristis
Primary: Cross-sectional Area (CSA) of Muscle Fibers — 2680; 2377; 2028; 1882 micron squared
N/A N=34 Optimizing Movement After Anterior Cruciate Ligament Injury
Anterior Cruciate Ligament Injuries · Knee Osteoarthritis
Primary: Knee Flexion Moment Impulse — 0.54; 0.50 Ratio — p=0.293
Phase 2 N=24 Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears
Anterior Cruciate Ligament Tear · Anterior Cruciate Ligament Rupture
Primary: Change in Synovial Interleukin (IL) -1 Receptor Antagonist Concentration — 13.8; 16; 9.9; 7.5 pg/ml
N/A N=67 Follow-Up Study Evaluating The Long Term Safety and Efficacy of BST-CarGel and Microfracture Repair of the Knee
Knee Injuries
Primary: Degree of Lesion Filling (%Fill) by Repair Tissue at Degree of Lesion Filling (%Fill) by Repair Tissue at 5 Years Through MRI. — 93.79; 86.96 Percentage of lesion filled…
N/A N=23 In Vivo Three-Dimensional Determination of Osteoarthritis Brace Effectiveness
Osteoarthritis, Knee
Primary: Medial Condylar Separation With Brace — 0.60 mm