N/A N=73 Drug Therapy to Treat Minor Depression
Depression
Primary: Efficacy Assessed Using the Inventory of Depressive Symptomatology - Clinician Rated (IDS-C) — -11.47; -9.35; -10.49 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=205 Depression Attention for Women Now (The DAWN Study)
Depressive Disorder
Primary: Depression Treatment Outcome — 0.96; 1.33 units on a scale
Phase 4 N=53 Effects of Treatment on Decision-making in Major Depression
Major Depressive Disorder · Healthy Controls
Primary: Money Earned — 23.2; 25.0; 20.5; 21.9 US Dollars
Phase 2 N=97 Assessing Symptomatic Clinical Episodes in Depression
Major Depressive Disorder
Primary: MADRS Score - Overall Change From Baseline — 13.7; 8.8 score on a scale — p=<.001
N/A N=168 Motivational Interviews for Depression in Primary Care
Major Depression
Primary: Depression Remission — 4; 15 participants
N/A N=2,452 Testing Scalable, Single-Session Interventions for Adolescent Depression in the Context of COVID-19
Depression
Primary: Change in Adolescent Depressive Symptom Severity — 14.31; 14.15; 14.22; 12.57 Score on a scale
Phase 4 N=15 Depressed Mood Improvement Through Nicotine Dosing (Depressed MIND Study)
Major Depressive Disorder
Primary: Change in Total MADRS (Montgomery Asberg Depression Rating Scale) Score — -18.45 units on a scale — p=<0.001
N/A N=73 Prevention of Depression in Spouses of People With Cognitive Impairment
Depression
Primary: Depressive Symptoms — 9.736; 11.785; 8.880; 12.300 units on a scale — p=<.05
N/A N=21 Treatment of Mild to Moderate Depression Symptoms in Patients With Spinal Cord Injury
Spinal Cord Injury
Primary: 16-Item Quick Inventory of Depressive Symptomatology - Self Report (QIDS-SR16) — 2; 0 participants — p=0.445
N/A N=9 European Deep Brain Stimulation (DBS) Depression Study
Depressive Disorder, Major
Primary: Mean Percent Change From Baseline in MADRS Score — -7.7; -7.4; -8.8; -6.2 percentage change from baseline
N/A N=28 Therapist-Guided Smartphone-Delivered CBT for MDD
Major Depressive Disorder
Primary: Drop-Out Rates — 2; 26 Participants
N/A N=57 Improving Depression Management
Depression
Primary: Patient Health Questionnaire (PHQ-9) — 12.6; 15.2 score on a scale
Phase 2 N=902 An Expert System to Reduce Depression in Primary Care
Depression · Depressive Disorder, Major
Primary: Change in Depression Severity — -5.4; -3.7 units on a scale — p=.003
Phase 3 N=126 Role of Magnesium Supplementation in the Treatment of Depression
Depression
Primary: Patient Health Questionnaire-9 — -4.28; -0.09 score on a scale
N/A N=64 Virtual Reality Compared to Screen Based Engagement on Mood
Virtual Reality
Primary: Change in Positive Affect and Negative Affect From Baseline to After a 2 Minute Mood Induction — 3.7; 4.63; 1.97; 1.56 units on a scale
N/A N=48 Standardized Versus Tailored Implementation of Measurement Based Care for Depression
Depression
Primary: Patient Health Questionnaire — 18.04; 16.77; 12.15; 13.09 score on a scale
N/A N=132 Novel Neural Circuit Biomarkers of Major Depression Response to CCBT
Depression · Major Depressive Disorder · Depressive Disorder
Primary: Resting State Functional Connectivity: MDD vs Controls — .51; .65; .54 Z normalized correlation
N/A N=39 Depression Intervention Among Gay and Bisexual Men Receiving Treatment for Methamphetamine Use
HIV/AIDS · Methamphetamine Abuse · Depression
Primary: Depression Symptoms Over Time — -0.062 Units on a Scale
N/A N=80 Problem Adaptation Therapy for Mild Cognitive Impairment and Depression
Cognitive Impairment · Depression
Primary: Change in Global Cognition Assessed by RBANS — 434.66; 435.36; 438.46; 436 Score on a Scale — p=0.9644
N/A N=31 Efficacy of Adjunctive Exercise for the Behavioral Treatment of Major Depression
Major Depressive Disorder
Primary: Montgomery-Asberg Depression Rating Scale (MADRS) — 11.2; 16.0 score on a scale
N/A N=149 PEERS Using Peer Mentors to Deliver Depression Care
Depression
Primary: Patient Health Questionnaire-9 — 6.66; 7.33; 7.89; 7.84 score on a scale — p=<0.0001
N/A N=649 Evaluation of a Mobile Therapy for Elevated Depressive Symptoms
Depressive Symptoms · Depression
Primary: Mean Score of Depressive Symptoms — -5.95; -11.24; -10.69 score on a scale
N/A N=30 Treatments for Improving Mood in Depressed Teens-3
Depression
Primary: Acceptability — 11; 13 Participants
Phase 3 N=598 Efficacy Study of Vortioxetine on Cognitive Dysfunction in Adult Patients With Major Depressive Disorder
Major Depressive Disorder
Primary: Change From Baseline to Week 8 in DSST (Number of Correct Symbols) and RAVLT (Acquisition and Delayed Recall) Using the Composite Z-score Defined as the Weighted Sum of…
N/A N=229 A Randomized Controlled Trial of PCIT-ED for Preschool Depression
Depressive Disorder, Major
Primary: Kiddie Schedule for Affective Disorders and Schizophrenia - Early Childhood (KSADS-EC) MDD Core Symptom Score — 1.74; 4.15 number of symptoms (0-9)
Phase 1 N=92 Healthy Minds Program App Dosage
Depression · Anxiety · Psychological Distress
Primary: Randomization Rate: Number of Participants Who Were Randomized and Completed EMA Assessments and Activities in the HMP App — 46; 46 Participants
N/A N=26 Transcranial Direct Current Stimulation Therapy for Major Depression
Major Depressive Disorder
Primary: Clinical Response — 22 Participants
N/A N=30 Intensive tDCS for MDD: Feasibility Study
Major Depressive Disorder
Primary: Change in Depressive Symptoms Measured by the Patient Health Questionnaire (PHQ-9) — 21; 31.5 percentage of change
N/A N=851 Study Comparing Remission Rates, in Patients With Major Depressive Disorder (MDD)
Major Depressive Disorder
Primary: Percentage of Participants With Remission Based on Hamilton Depression Scale (HAM-D) — 54.4 Percentage of participants
Phase 2 N=7 Treatment of Young Adults With Comorbid AUD/MDD: A Pilot Medication Trial
Major Depressive Disorder · Alcohol Use Disorder
Primary: Drinks Per Drinking Day — 2.8; 2.0 Drinks per drinking day