N/A N=1,206 Epidemiology of Depression, Anxiety, and Cognitive Impairment
Depression · Anxiety · Cognitive Impairment
Primary: Participants With Depression by Patient Health Questionnaire - 9 — 177 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=95 Stress and Inflammation in Late-Life Depression
Depression · Inflammation
Primary: IL-6 Levels — 5.25; 18.24; 3.69; 6.84 pg/mL — p=.44
Phase 4 N=121 Emotional and Cognitive Control in Late-Onset Depression
Depression
Primary: Change in Depression Severity (Measured by Montgomery Asberg Depression Rating Scale) — 25.26; 1.03; 13.78; 1.08 score on a scale — p=< 0.025
Phase 4 N=47 A Study of L-DOPA for Depression and Slowing in Older Adults
Major Depressive Disorder · Dysthymia · Depression Not Otherwise Specified
Primary: Hamilton Rating Scale for Depression (24 Item) — 10.94 Units on a Scale
N/A N=149 PEERS Using Peer Mentors to Deliver Depression Care
Depression
Primary: Patient Health Questionnaire-9 — 6.66; 7.33; 7.89; 7.84 score on a scale — p=<0.0001
N/A N=181 Preventing Depression in Late Life: A Model for Low and Middle Income Countries
Depression · Anxiety Disorder
Primary: Percent of Participants Who Develop Major Depression and Anxiety Disorders — 4; 13 Participants — p=0.04
N/A N=88 Post-traumatic Stress Disorder (PTSD) Symptoms in Later Life
Post Traumatic Stress Disorder
Primary: The Trauma History Questionnaire (THQ; Green, 1996) — 5.93; 0.76; 3.81; 0.97 score on a scale
N/A N=30 Using Peer Mentors to Deliver Depression Care
Depression
Primary: Depression With PHQ-9 — 7.7 units on a scale
N/A N=23 A Family-based Primary Care Intervention to Enhance Older Men's Depression Care
Major Depression
Primary: Depressive Symptoms — 14.8; 15.3; 10.1; 13.0 units on a scale
Phase 4 N=30 Duloxetine Treatment in Elderly With Dysthymia
Depression · Dysthymic Disorder
Primary: Change in Hamilton Rating Scale for Depression (HAM-D, 24-item) From 0 Weeks to 12 Weeks. — 8 units on a scale — p=<0.001
N/A N=94 Medication Treatment for Depression in Nursing Home Residents
Depression
Primary: Geriatric Depression Scale (GDS) Score — 5.11; 5.03; 4.59; 4.64 units on a scale
N/A N=47 Online Peer Networked Collaborative Learning for Managing Depressive Symptoms
Depression
Primary: Patient Health Questionnaire - 9 (PHQ-9) - Depression Severity Module — -5.4; -4.8; -1.1 units on a scale — p=< .001
N/A N=28 Enhancing Well-Being Through Exercise During Old Age
Depression · Osteoarthritis
Primary: Attendance of the Fit & Strong! Intervention Classes — 10 Classes attended
N/A N=169 Prognosis of Depression in the Elderly (PRODE). A Multicentre, Longitudinal Study of Elderly Depressed Patients.
Depression · Dementia
Primary: Depression — 48 participants
Phase 4 N=100 Antidepressant Response in the Treatment of Depressive Symptoms and Frailty Characteristics in Older Adults
Major Depressive Disorder · Dysthymic Disorder · Depressive Disorder, NOS
Primary: Hamilton Rating Scale for Depression (HRSD) — 13.3 score on a scale
Phase 4 N=106 Aging Brain Changes, Executive Dysfunction and Depression
Depression
Primary: Hamilton Depression Rating Scale. — 8.09 units on a scale
Phase 4 N=25 Treating Hearing Loss to Improve Mood and Cognition in Older Adults
Hearing Loss · Depression
Primary: Hamilton Rating Score for Depression (HRSD) — 12.04; 13.86 score on a scale
Phase 4 N=56 Vilazodone for Treatment of Geriatric Depression
Major Depressive Disorder
Primary: Hamilton Depression Rating Scale (HDRS) — 17.2; 16.6; 7.6; 7.5 units on a scale
Phase 4 N=95 Brain Aging and Treatment Response in Geriatric Depression
Mild Cognitive Impairment (MCI) · Depression
Primary: Change in Hamilton Depression Rating Scale — 17.8; 17.7; 6.0; 6.7 units on a scale
N/A N=108 Mechanisms of Antidepressant Non-Response in Late-Life Depression
Major Depressive Disorder
Primary: Hamilton Rating Scale for Depression (HRSD) — 22.8; 23.6; 22.9 units on a scale
N/A N=65 Reward Function and Therapy for Late-Life Depression
Major Depressive Disorder
Primary: Change in Late Positive Potential to Rewarding Stimuli — 0.80; 0.07 microvolts — p=.08
N/A N=202 Shared Decision-Making for Elderly Depressed Primary Care Patients
Depression
Primary: Number of Participants Who Adhered to Physician Recommended Treatment — 40; 16 Participants
N/A N=80 Coping With Depression in Parkinson's Disease
Parkinson's Disease · Depression
Primary: Hamilton Depression Rating Scale: Baseline — 20.93; 19.38 units on a scale
N/A N=38 Cognitive Fitness for Depression in Older Adults
Depression Mild · Depressive Disorder, Major · Mild Cognitive Impairment
Primary: Trail Making Part B Test — 5.06; -1.55 seconds
Phase 3 N=35 Memantine Plus Es-citalopram in Elderly Depressed Patients With Cognitive Impairment
Mild Cognitive Impairment · Major Depressive Disorder · Alzheimer's Disease
Primary: Change in Selective Reminding Test - Total Immediate Recall (SRT-IR) — 7.5 units on a scale
Phase 4 N=110 Antidepressant Treatment of Melancholia in Late Life
Depression · Melancholia
Primary: HAMILTON Rating Scale for DEPRESSION Range — 27.3; 27.1; 10.7; 8.4 units on a scale — p=<0.05
N/A N=141 Treatment of Depressed Chronic Obstructive Pulmonary Disease Patients
Pulmonary Disease, Chronic Obstructive · Major Depression
Primary: Composite Antidepressant Score Scale (CAD) — 29; 25; 9; 20 Participants
Phase 2 N=15 Buprenorphine for Late-Life Treatment Resistant Depression
Depression
Primary: Montgomery Asberg Depression Rating Scale — 9.5 units on a scale
N/A N=174 Telehealth Cognitive Behavioral Therapy for Depression in Parkinson's Disease (PD)
Depression · Parkinson's Disease
Primary: Hamilton Depression Rating Scale — 16.46; 21.37; 16.35; 20.70 score on a scale
N/A N=62 Social Connections and Late Life Suicide
Depression · Suicidal Ideation
Primary: Social Connectedness — 4.33; 4.30; 0.77; 0.82 score on scale — p=.278