N/A N=40 A More Physiological Feeding Process in ICU:the Intermittent Infusion With Semi-solidification of Nutrients
Nutrition, Enteral
Primary: the Ratio of the Enteral Nutrition — 0.98; 0.73 ratio
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=27 Preliminary Efficacy, Safety and Pharmacokinetics Study of Nepadutant in Infant With Feeding Intolerance
Colic
Primary: The Absolute Differences of I-GERQ-R Total Score at V3 (End of First Week of Treatment) Respect to the Baseline (V2). — -6.8; -7.6; -6.8 score on a scale
Phase 2 N=13 A Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Single Dose of Intravenous TD-8954 Compared With Metoclopramide in Critically Ill Patients With Enteral Feeding Intolerance
Enteral Feeding Intolerance
Primary: Adverse Events — 5; 4 participants
Phase 2 N=18 Early Supplementation of Enteral Microlipid With and Without Fish Oil in Premature Infants With Enterostomies
Prematurity · Intestine Perforation · Necrotizing Enterocolitis (NEC)
Primary: The Serum Biomarkers of Inflammatory Cytokines
N/A N=2,410 Impact of Early Enteral vs. Parenteral Nutrition on Mortality in Patients Requiring Mechanical Ventilation and Catecholamines
Acute Respiratory Failure · Shock
Primary: Mortality — 422; 443 Participants
N/A N=5,824 Comparison of Outcomes Between Parenteral and Enteral Nutrition
Deglutition Disorders
Primary: Mortality Calculated From Outcome Section From DPC Database at 90 Days — 359; 287 Participants
Phase 4 N=20 INF108F in Infants With Food Protein Induced Proctocolitis
Infant Development · Gut Microbiome · Food Protein Induced Allergic Proctocolitis
Primary: Changes to Gut Microbiome Composition — 42.816; -12.413 Change in %B.infantis reads (Day 28-BL) — p=0.154
N/A N=124 Enteral Nutrition as Stress Ulcer Prophylaxis in Critically Ill Patients.
Gastrointestinal Hemorrhage · Clostridium Difficile Colitis
Primary: Number of Subjects With GI Bleeding — 1; 1 participants
N/A N=34 Safety, Tolerability and Fat Absorption Using Enteral Feeding In-line Enzyme Cartridge (Relizorb)
Exocrine Pancreatic Insufficiency
Primary: Number of Patients With Adverse Events and Unanticipated Adverse Device Effects — 4; 6; 1; 2 Participants
N/A N=119 DrIFT 2 Study: Displacement in Feeding Tubes
Enteral Nutrition
Primary: Tube Migration — 6 Participants
Phase 1 N=44 Intestinal Permeability in Preterm Infants
Prematurity · Intestinal Permeability
Primary: Intestinal Permeability — 0.0731; 0.0720 ratio — p=0.932
Phase 3 N=100 Study Comparing a Soybean Oil-Based With an Olive Oil-Based Lipid Emulsion in ICU Patients Requiring TPN
Parenteral Nutrition
Primary: Number of New Nosocomial Infections After 48 Hrs of Parenteral Nutrition (PN) Between the 2 Groups During Their Hospital Stay — 21; 29 number of nosocomial infections
N/A N=1,059 Enhanced Protein-Energy Provision Via the Enteral Route in Critically Ill Patients
Critically Ill
Primary: Percentage of Prescribed Calories From Energy — 32; 34.2; 43.6; 33.6 percentage of prescription
N/A N=10 Novel Blood Test to Predict Safe Foods for Infants and Toddlers With Food Protein-induced Enterocolitis Syndrome (FPIES)
Food Protein-Induced Enterocolitis Syndrome · Allergies · Pediatric Disorder
Primary: Negative Predictive Value (NPV), Defined as the Percentage of Test-predicted Safe Foods That Are Actually Safe Foods. — 98.5; 73.16 percentage — p=<0.0001
N/A N=36 Nutritional Status and Enteral Absorption Capability After Brain Death
Brain Death
Primary: Primary Outcome Measure is IL-6 Level — 565.5; 264.9 pg/ml
N/A N=151 Optimal Feeding Tube Dwell Time in VLBW Infants to Reduce Feeding Tube Contamination
Infection
Primary: Amount of Contamination — 357,000,000; 4,820,000,000 Colony forming units
N/A N=52 Optimal Feeding Tube Placement
Enteral Feeding Intolerance
Primary: Duration of Time — 19; 2.5 Minutes
Phase 2 N=200 Efficacy of Enteral Iron Supplementation in Critical Illness
Anemic, Critically Ill Patients
Primary: Hematocrit — 29.3; 29.1; 28.6; 28.2 percentage of RBC in blood
N/A N=18 Effect of Elemental Diet on Adult Patients With Eosinophilic Gastroenteritis
Eosinophilic Gastroenteritis
Primary: Percent of Participants in Complete Histologic Remission — 100 percentage of participants
N/A N=452 Study of Impact of Not Measuring Residual Gastric Volume on Nosocomial Pneumonia Rates
Ventilation-Associated Pneumonia
Primary: Compare Ventilator Associated Pneumonia Rates in Patients Receiving Early Enteral Feeding Without Residual Gastric Volume (RGV) Monitoring and in Patients With RGV…
Phase 3 N=305 Impact of SPN on Infection Rate, Duration of Mechanical Ventilation & Rehabilitation in ICU Patients
Critically Ill
Primary: Documented Infection Rate — 58; 41 Infections
Phase 3 N=40 Prospective Randomized Clinical Trial of Intravenous Lipids and Cholestasis
Parenteral Nutrition Associated Cholestasis
Primary: Number of Participants With Parenteral Nutrition Associated Cholestasis — 6; 6 Participants — p=0.94
N/A N=100 Nutrition Monitoring and Feeding Optimization With the smART+ System - Comparative Study
Aspiration Pneumonia · Malnutrition
Primary: Nutrition Optimization — 89.5; 65 percentage of feeding efficiency
N/A N=146 Aspiration of Residual Gastric Contents
Infant, Premature · Nutrition, Enteral
Primary: Enteral Intake on Day of Life 7 — 27.5; 22.6 mL/kg per day — p=0.27
N/A N=48 Feasibility Study to Evaluate Safety of ENvizion Medical™ ENVUE™ System
Enteral Nutrition
Primary: Number of Participants With Successfully Placed Enteral Feeding Tube — 43 Participants
N/A N=28 Comparison of Feeding Strategies for Hypoplastic Left Heart Syndrome Infants
Hypoplastic Left Heart Syndrome · Growth Failure
Primary: Weight Gain in Grams Per Day — 24.3; 23.6 grams/day — p=0.05
Phase 3 N=2 Omegaven as Alternative Parenteral Fat Nutrition
Cholestasis · Cholestasis of Parenteral Nutrition
Primary: Number of Participant With Decrease in Direct Bilirubin Level — 2; 0 Participants
Phase 3 N=196 Effects of Voluven on Hemodynamics and Tolerability of Enteral Nutrition in Patients With Severe Sepsis
Sepsis
Primary: Amount of Study Drug Required to Achieve Initial Hemodynamic Stabilization — 1379; 1709 Milliliter — p=0.0185
Phase 3 N=21 Standard Lipid Therapy vs IVFE Minimization for Prevention of PNALD
Cholestasis
Primary: Rate of Rise of Direct Bilirubin as a Function of Time — 1.033001353; 1.05457485; 1.025504411; 1.049318179 mg/dL/day
Phase 3 N=500 Supplemental Enteral Protein in Critical Illness
Nutrition Disorder · Trauma · Critical Illness
Primary: Serum Concentrations of Transthyretin at 3 Weeks After Injury. — 18.1; 18.9 mg/dl