N/A N=818 Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
Labor Pain · Pregnancy
Primary: Delivered by Cesarean Section — 134; 126 participants — p=0.65
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=104 Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Termination of Pregnancy Analgesia
Medical; Abortion, Fetus
Primary: Incidence of Motor Block — 24; 3 participants — p=< 0.001
N/A N=100 Patient Education on Labor Analgesia Options
Labor Analgesia
Primary: Survey to Determine Utility and Effect of Educational Materials — 79; 21; 93; 7 percentage of patients responding — p=<0.0001
Phase 3 N=45 Bupivacaine With Epidural Volume Extension
Spinal Anesthesia · Epidural; Anesthesia
Primary: Time Until PACU Discharge in Minutes — 135; 50 minutes
Phase 4 N=101 Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain
Labor Pain
Primary: Number of Subjects With Success Rate at 15 Minutes Post-epidural Bolus Injection — 31; 38 Participants — p=0.38
Phase 4 N=44 2 Dose Neuraxial Morphine for Prevention of PDPH
Postdural Puncture Headache
Primary: Number of Participants With Postdural Puncture Headache — 3; 4; 8; 10 Participants
Phase 2 N=66 The Prevention of Hypotension After Epidural Analgesia After Major Surgery
Hypotension · Pain
Primary: Changes Between the 3 Groups Assessed by Blood Pressure Measurement — 5; 2; 3; 10 Participants — p=0.165
Phase 4 N=228 Epidural Morphine Following Vaginal Delivery
Pain
Primary: The Number of Women Who Received Systemic Narcotic Analgesics in the First 24 Hours Postpartum — 8; 37 participants — p=0.05
Phase 3 N=192 Wound Infusion vs Spinal Morphine for Post-caesarean Analgesia
Post Caesarean Analgesia
Primary: Duration of Effective Analgesia — 351; 380; 247 minutes
Phase 4 N=80 Spinal or Epidural Fentanyl or Sufentanil for Labour Pain in Early Phase of the Labour
Labor Pain
Primary: Change of Maximum Pain During Contraction at 20 Minutes After the Study Drug Delivery — 60; 36; 67; 42 mm
N/A N=57 Does Maternal Fever During Labor Analgesia Has Any Relationship With Maternal Ventilation?
Pregnancy
Primary: Changes in Maternal Ventilation During Labor Analgesia — 15.3; 12.6; 13.8 L/min
Phase 4 N=41 Effect of Preemptive Epidural Analgesia in Labor on Cytokine Production
Obstetric Pain
Primary: Maternal Cytokine IL-10 Levels of pg/ml Upon Enrollment — 12.7; 14.2 pg/ml
Phase 4 N=179 Comparison of PIEB vs CEI for Labor Analgesia
Labor Pain
Primary: Volume of Local Anesthetic Received Through Patient Controlled Epidural Analgesia (PCEA) Per Hour — 4.03; 4.52 milliliters per hour — p=0.17
Phase 1 N=200 Epidural Neostigmine for Labor Pain
Labor Pain
Primary: Amount of Drug Consumed Per Hour in Each Group(Arm) — 16.2; 14.6; 15.3; 16 milliliters per hour
Phase 3 N=104 Epidural Anesthesia Within an Enhanced Recovery Pathway in Reducing Pain in Patients Undergoing Gynecologic Surgery
Intraoperative Complication · Malignant Female Reproductive System Neoplasm · Pain
Primary: Relative Pain Scores, as Measured by the Pain Numeric Rating Scale (NRS) — 3.87; 4.95 score on a scale
Phase 4 N=141 DPE Technique in Labor Epidural for Morbidly Obese Women
Morbid Obesity · Labor Pain
Primary: Number of Participants Who Required Asymmetric Block, Top-up Interventions, Catheter Adjustments, Replacement of Epidural Catheter, or Failure of Block Requiring…
Phase 4 N=67 Infiltration Analgesia After Caesarean Section
Pain, Postoperative · Caesarean Section
Primary: The Demand of Rescue Analgesics (Oxycodone) — 47.5; 57.8 mg — p=0.10
Phase 4 N=120 Programmed Intermittent Bolus Dosing Versus Continuous Epidural Infusion for Epidural Analgesia in Abdominal Surgery.
Pain, Acute
Primary: Total Local Anesthetic Utilized in First 24 Hours — 126; 123 mg — p=0.74
Phase 4 N=120 Multimodal Pain Management for Cesarean Delivery
Pain
Primary: Total Opioid Intake in Morphine Milligram Equivalents in the First 48 Hours After Cesarean Delivery (CD) — 42; 49.5 morphine milligram equivalents
Phase 3 N=96 Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens
Morbid Obesity · Postoperative Pain · Postoperative Bowel Function
Primary: Change From Baseline in Pain Scores (Visual Analogue Scale) — 1.4; 1.6; 1.6; 0.8 units on a scale
N/A N=140 Dural Puncture Epidural Versus Epidural Anesthesia for Cesarean Delivery
Pain Levels
Primary: Onset Time of Surgical Anesthesia — 422; 655 seconds
Phase 4 N=67 Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries
Pain · Postpartum Depression
Primary: Perineal Pain in Postpartum Patients 1 Week After Obstetric Anal Sphincter Injuries. — 3.5; 2.7; 2.4 score on a scale
Phase 4 N=80 Recovery and Analgesia After Surgery for Gynecological Cancer
Gynecological Cancer
Primary: Length of Stay — 4.3; 3.3 days
N/A N=90 Analgesia After Total Hip Arthroplasty: Peri-Articular Injection Versus Epidural Patient Controlled Analgesia (PCA)
Osteoarthritis
Primary: Time Until Patient is Ready for Discharge — 2.4; 2.3 days
Phase 4 N=42 ED90 for Hyperbaric Bupivacaine in Super Obese Parturients
Obesity, Morbid · Spinal Anesthesia · Cesarean Delivery
Primary: Number of Participants With Successful Blocks for Induction (Success Induction) — 1; 3; 27; 11 Participants
N/A N=61 CSE v. Epidural for Postpartum Depression
Depression, Postpartum · Labor Pain
Primary: Edinburgh Postnatal Depression Score (EPDS) — 4.23; 4.71 score on a scale — p=0.7463
N/A N=80 Ultrasound-Guided Landmark and Epidural Site Pain
Back Pain · Epidural Analgesia, Obstetric
Primary: Epidural Pressure Sensitivity at Level of Epidural Insertion — 26.8; 26.8; 47.6 force (newtons/cm^2)
Phase 4 N=602 Prophylactic Ephedrine and Combined Spinal Epidurals for Labor
Labor Pain
Primary: Early Profound Fetal Bradycardia — 8; 14 participants — p=0.18
N/A N=18 Use of Ultrasound Guidance to Assist With Labor Epidural Placement in Patients With a BMI ≥40
Labor Pain
Primary: Total Time Required for Epidural Catheter Placement — 6.1; 11.0 Minutes
N/A N=91 Intrapartum Epidural Catheter Displacement: Dressing Methods
Analgesia, Obstetrical
Primary: Epidural Catheter Migration — 44; 25; 17 percentage patients catheter migration