Phase 2 N=16 D-cycloserine and Treatment of Feeding Disorders
Feeding Disorders · Specific Phobia
Primary: Rapid Swallowing — 18.6; 14.3 percentage of bites
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=30 Parent Acceptance and Commitment Therapy (PACT) for Parents of Children With Pediatric Feeding Disorder
Pediatric Feeding Disorder, Chronic · Pediatric Feeding Dysfunction, Acute
Primary: Patient Health Questionnaire-9 (PHQ-9) — 2; 0; 12; 0 Participants
N/A N=71 Learning to Love Mealtime Together
Infant Obesity · Parenting · Feeding Behavior
Primary: Infant Weight-for-Length Z Scores — 0.43; 0.12 z-score — p=0.07
Phase 2 N=21 Trial of Amitriptyline for Chronic Oral Food Refusal in Children 9 Months to 8 Years of Age
Chronic Oral Food Refusal
Primary: % Calories Taken Orally — 68.62; 76.89 change in percent kcal obtained orally
N/A N=109 Mechanisms and Management of Infant Dysphagia
Dysphagia · Airway Aspiration · Airway Penetration
Primary: Number of Participants With Successful Safe Oral Feeding — 51; 31 Participants — p=0.008
N/A N=56 Evaluation of an Interdisciplinary Decision Guide for Infant Feeding Assessment
Premature Birth · Feeding and Eating Disorders of Childhood
Primary: Number of Participants That Recommend Feeding Therapy — 27; 27; 1; 1 Participants
Phase 4 N=70 iKanEat: A Randomized-controlled, Multi-center Trial of Megestrol for Chronic Oral Food Refusal in Children
Feeding Behavior · Feeding Disorder of Infancy or Early Childhood
Primary: Participants Who Transitioned to Oral Feeding — 23; 24 Participants
N/A N=132 An Integrated Nutrition Intervention to Promote Healthy Eating Habits for Children With ASD
Autism Spectrum Disorder
Primary: Change in Fruit and Vegetable Intake From Baseline, as Measured by the Daily Amount of Fruit and Vegetables Consumed by Children — 0.313; -0.045; 0.549; -0.077 cup…
N/A N=40 The Effects of Neurodevelopmental Therapy on Feeding and Swallowing.
Cerebral Palsy
Primary: Gross Motor Function Classification System (GMFCS) — 4; 2; 0; 0 Participants
N/A N=34 Healthy Start to Feeding Intervention
Weight, Body · Diet Habit
Primary: Weight-for-Length Percentile — 44.94; 46.70; 58.69; 48.54 Percentile
N/A N=101 Effects of Prefeeding Oral Stimulation on Feeding Performance in Preterm Infants
Preterm Infant · Oral Feeding Performance
Primary: Length of Transition Period — 16.0; 16.9 days — p=0.63
N/A N=159 Development of Eating Disorders Symptoms Among Children
Eating Disorders Symptoms
Primary: Number of Participants With >20 on the 26 Children Eating Attitudes Test — 26; 4 Participants
N/A N=99 Fear, Gastrointestinal Distress, and Interoception: Physiological and Psychological Mechanisms in Eating Disorders
Feeding and Eating Disorders
Primary: Subjective Rating of Fear — -36.9444; -23.9219; -47.3611; 85.6250 units on scale*minutes — p=.879
N/A N=16 BabyStrong Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) Paired Bottle Feeding to Improve Oral Feeding
Infant Feeding Problems, taVNS
Primary: Bradycardia — 0; 0; 0; 0 Participants
N/A N=164 Obesity Prevention in Head Start
Childhood Obesity
Primary: Change in Percentage of Children Over-consuming Energy During Lunch Attributable to Mealtime Matters — -10.9; -56.5 Percent of Participants
Phase 2 N=38 Treatment of Hyperphagia Behavioral Symptoms in Children and Adults Diagnosed With Prader-Willi Syndrome
Hyperphagia in Prader-Willi Syndrome
Primary: Change From Baseline in Hyperphagia in Prader-Willi Syndrome (PWS) Questionnaires- Responsiveness (HPWSQ-R) Total Score at End-of-treatment (Day 15) — -15.6; -8.9 score…
N/A N=28 Comparison of Feeding Strategies for Hypoplastic Left Heart Syndrome Infants
Hypoplastic Left Heart Syndrome · Growth Failure
Primary: Weight Gain in Grams Per Day — 24.3; 23.6 grams/day — p=0.05
Early Phase 1 N=35 taVNS Paired With Bottle Feeding in Infants Failing Oral Feeds
Poor Feeding · Infant Development · Vagus Nerve Stimulation
Primary: Number of Infants Who Took All Feeds by Mouth (Responders) — 8; 11 Participants
N/A N=3,188 Low-birthweight Infant Feeding Exploration
Low Birthweight · Pre-Term
Primary: Length-for-Age Z-score — -1.43 Z-score
N/A N=251 Nutritional Education and the Prevention of Iron Depletion in Children 9 Months to 2 Years
Iron Deficiency
Primary: The Primary Outcome is Iron Depletion, and Will be Defined as Serum Ferritin <10 mcg/L. — 64; 71; 13; 10 participants — p=0.42
N/A N=38 Mobile Health (mHealth) Nutrition Intervention for Children With Autism Spectrum Disorder
Diet Modification
Primary: 3-month Fruit and Vegetable Intake — 2.16; 3.01 Servings per day
N/A N=255 Promoting The Self-Regulation Of Energy Intake
Obesity
Primary: Children's BMI Percentiles — 49; 41; 15; 18 Participants — p=<0.05
Early Phase 1 N=13 Dopamine Receptor Contributions to Prediction Error and Reversal Learning in Anorexia Nervosa
Anorexia Nervosa
Primary: Measurement of Brain Activation (Measured in Percent Signal Change) During a Prediction Error Taste Reward Task Using Functional Magnetic Resonance Imaging (fMRI)…
N/A N=22 A Study of Neurophysiologically Based Occupational Therapy Intervention (NBOTI) for Feeding in the NCCU.
Cerebral Palsy · Sensorimotor Deficits · Sensory Processing Disorder
Primary: A Priori H1. The Number of Days to Achieve Oral Feeding Between the Intervention Group and the Matched Historical Comparison Group - From All Tube to All Oral Feeding…
N/A N=38 Feeding and Wellness Among Late Preterm Infants
Late Preterm Infant
Primary: Phone Call Completion Rate — 194; 102; 59; 52 calls
N/A N=189 Direct Swallowing Training and Oral Sensorimotor Stimulation in Preterm Infants
Premature Birth of Newborn · Intervention Studies
Primary: Days From Start to Independent Oral Feeding — 21.1; 17.2; 14.8 days
N/A N=177 Shifting Perspectives: Enhancing Outcomes in Anorexia Nervosa With CRT
Anorexia Nervosa
Primary: Change in Cognitive Flexibility - Condition 4 Trail Making Test of DKEFS — 11.89; 10.94; 11.47; 11.14 score on a scale — p=.507
N/A N=76 Neonatal Gastro-Esophageal Reflux Disease (GERD) Management Trial
Gastroesophageal Reflux Disease
Primary: CLINICAL OUTCOME OF FEEDING SUCCESS — 33; 44 percentage of participants — p=0.28
N/A N=130 Maternal Role in Oral Feed Establishment in Preterm Neonates
Preterm Birth · Tube Feeding · Swallowing Disorder
Primary: Transition Time to Full Oral Feeding — 10; 9 days
Phase 3 N=129 SOFEED: Six Food vs. One Food Eosinophilic Esophagitis Diet Study
Eosinophilic Gastrointestinal Disorders (EGIDs) · Eosinophilic Esophagitis (EoE)
Primary: Percent of Participants in Histologic Remission (<15 Eos/Hpf) — 34.3; 40.3 percentage of participants — p=0.58