N/A N=57 Does Maternal Fever During Labor Analgesia Has Any Relationship With Maternal Ventilation?
Pregnancy
Primary: Changes in Maternal Ventilation During Labor Analgesia — 15.3; 12.6; 13.8 L/min
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=345 The Effect of Neuraxial Analgesia on Maternal Breastfeeding
Pain · Breastfeeding
Primary: Breastfeeding at 6 Weeks Post Delivery — 100; 99; 102; 3 Participants — p=.34
N/A N=276 Pulse Pressure and Post-epidural Fetal Heart Rate Changes
Fetus or Neonate Affected by Maternal Epidural Anesthesia During Labor and Delivery
Primary: Incidence of New-onset Category II or III Fetal Heart Rate Tracings — 72; 52 Participants
N/A N=212 Intrapartum Maternal Oxygen Supplementation: Effects on the Mother and Neonate
Intrauterine Resuscitation
Primary: Umbilical Artery Malondialdehyde — 9.8; 10.2 umol/L
N/A N=2,162 The Association Between Decreasing Labor Analgesia Epidural Infusion and Forceps Delivery
Labor Pain · Pregnancy
Primary: Number of Parturients With a Decrease in the Infusion of Epidural Analgesia During Second Stage of Labor — 146; 51 participants — p=<0.01
Phase 4 N=41 Effect of Preemptive Epidural Analgesia in Labor on Cytokine Production
Obstetric Pain
Primary: Maternal Cytokine IL-10 Levels of pg/ml Upon Enrollment — 12.7; 14.2 pg/ml
Phase 4 N=602 Prophylactic Ephedrine and Combined Spinal Epidurals for Labor
Labor Pain
Primary: Early Profound Fetal Bradycardia — 8; 14 participants — p=0.18
Phase 4 N=101 Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain
Labor Pain
Primary: Number of Subjects With Success Rate at 15 Minutes Post-epidural Bolus Injection — 31; 38 Participants — p=0.38
Phase 4 N=310 Effects of Bupivacaine Induced Motor Blockade During the Second Stage of Labor
Pregnancy
Primary: The Duration of the Second Stage of Labor — 75; 73 minutes — p=0.17
Early Phase 1 N=70 Comparison of Chloroprocaine vs Lidocaine for Epidural Anesthesia in Cesarean Delivery
Surgical Anesthesia, Cesarean Section
Primary: The Onset Time to Surgical Anesthesia — 558; 655 seconds — p=0.10
N/A N=110 Phenylephrine in Spinal Anesthesia in Preeclamptic Patients
Preeclampsia · Hypotension
Primary: The Umbilical Artery pH — 7.22; 7.20 pH — p=.38
Phase 3 N=40 Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine 2% for Cesarean Section Under Spinal Anesthesia
Pregnant Women · Pain · Hypotension
Primary: Time to Regression of Motor Block — 180; 130 minutes
N/A N=23 Changes in Tissue and Cerebral Oxygenation Following Spinal Anesthesia in Neonates, Infants, and Children
Infants Undergoing Surgery
Primary: Cerebral Non-invasive Near Infrared Spectroscopy (NIRS) — 0.05 percentage change per minute
Phase 4 N=80 Spinal or Epidural Fentanyl or Sufentanil for Labour Pain in Early Phase of the Labour
Labor Pain
Primary: Change of Maximum Pain During Contraction at 20 Minutes After the Study Drug Delivery — 60; 36; 67; 42 mm
Phase 4 N=228 Epidural Morphine Following Vaginal Delivery
Pain
Primary: The Number of Women Who Received Systemic Narcotic Analgesics in the First 24 Hours Postpartum — 8; 37 participants — p=0.05
N/A N=818 Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
Labor Pain · Pregnancy
Primary: Delivered by Cesarean Section — 134; 126 participants — p=0.65
Phase 4 N=20 Awake Caudal Catheter vs General Anesthesia
Inguinal Hernia
Primary: Number of Participants With Return to Baseline Respiratory Function. — 11; 9 Participants
Phase 2 N=8 Ketamine to Improve Recovery After Cesarean Delivery - Part 1
Obstetric Pain · Postpartum Depression · Breastfeeding
Primary: Ketamine (AUC) — 28.46 mcg*min/mL
Phase 4 N=81 Phenylephrine vs. Norepinephrine Infusion After Spinal Anesthesia for Cesarean Delivery
Effects of; Anesthesia, in Labor and Delivery
Primary: Number of Rescue Boluses to Maintain SBP — 25; 21 rescue boluses — p=0.12
N/A N=19 Fetal Neurobehavior in Non-methadone Maintained Women in Substance Abuse Treatment
Pregnancy · Drug Abuse
Primary: Fetal Heart Rate — 142.34 beats per minute
Phase 2 N=45 Comparison of Intratechal Levobupivacaine and Adding With Sufetanil and Fentanyl in Ceserean Section
Anesthesia
Primary: Number of Participants With Adverse Events as a Measure of Safety and Tolerability — 5; 10; 9 participants
Phase 4 N=141 DPE Technique in Labor Epidural for Morbidly Obese Women
Morbid Obesity · Labor Pain
Primary: Number of Participants Who Required Asymmetric Block, Top-up Interventions, Catheter Adjustments, Replacement of Epidural Catheter, or Failure of Block Requiring…
Phase 4 N=120 Multimodal Pain Management for Cesarean Delivery
Pain
Primary: Total Opioid Intake in Morphine Milligram Equivalents in the First 48 Hours After Cesarean Delivery (CD) — 42; 49.5 morphine milligram equivalents
N/A N=150 Presence of a Companion During Performance of Neuraxial Labor Analgesia
Anxiety · Pain · Health Knowledge, Attitudes, Practice
Primary: Maternal Satisfaction and the Presence of a Companion During the Placement of Epidural Catheter for Labor Analgesia. — 2; 2; 3; 0 Participants — p=.001
Phase 4 N=91 Comparison of Surgical Conditions in Cesarean Section Under General Anesthesia With Deep Neuromuscular Blockade Versus Succinylcholine
Cesarean Section
Primary: Induction to Delivery Interval — 268; 276 seconds
N/A N=204 Use of Peanut Labor Ball Following Epidural Anesthesia
Pregnancy
Primary: Delivery Rate — 31; 21 participants
Phase 3 N=127 Fetal and Infant Effects of Maternal Buprenorphine Treatment
Neonatal Abstinence Syndrome
Primary: Fetal Heart Rate — 145.7; 143.3; 138.6; 136.3 beats per minute — p=0.001
N/A N=89 The Effect of Anesthesia on Neurodevelopmental Outcome (NDO)
Anesthesia; Adverse Effect · Congenital Heart Disease · Neurodevelopmental Disorders
Primary: Bayley III — 91; 93; 88; 90 score on a scale
Phase 4 N=43 Outcomes of Neuraxial Anesthetic Technique on the Trial of Labor After Cesarean (TOLAC)
Labor Pain · Complications; Cesarean Section · Pregnancy
Primary: Number of Participants With Vaginal Birth After Cesarean (VBAC) — 12; 22 Participants
N/A N=80 Ultrasound-Guided Landmark and Epidural Site Pain
Back Pain · Epidural Analgesia, Obstetric
Primary: Epidural Pressure Sensitivity at Level of Epidural Insertion — 26.8; 26.8; 47.6 force (newtons/cm^2)