N/A N=278 Impact of the Lab-score on Antibiotic Prescription Rate in Children With Fever Without Source
Fever Without Source
Primary: Antibiotic Prescription Rate — 54; 59 participants — p=1
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=1,492 The Etiology of Acute Febrile Illness Requiring Hospitalization
Acute Febrile Illness
Primary: The Etiologies (Bacteria, Viruses, Parasites, Fungi and Others) of Fever Illness Expressed in Percentages of Enrolled Subjects. — 621; 362; 15; 5 Participants
N/A N=108 Hospital Admissions in Children Aged 3 Months to 5 Years Presenting With Fever to the Emergency Department
Fever
Primary: Number of Participants With Admission to Hospital Due to Parental High Levels of Worry — 87 Participants
N/A N=7,247 Personalised Risk Assessment in Febrile Illness to Optimise Real-life Management Across the European Union (PERFORM)
Fever · Infection · Inflammation
Primary: Number of Participants With Clinically-assigned Retrospective Phenotype — 655; 0 Participants
N/A N=1,046 Febrile Illness in Kinshasa and Kimpese
Febrile Illness
Primary: Proportion of Survival With Symptom Resolution — 96.9 percentage of participants
Phase 4 N=20 Temperature Control in Central Fever in the Neuro-ICU
Fever · Brain Hemorrhage
Primary: Core Temperature as Measured With an Approved Device (Urinary Catheter) in Place for Usual Clinical Care — 100.8; 100.3; 99.9; 99.5 degrees F
N/A N=93 Rapid Flu Tests in Travelers With Fever
Influenza
Primary: Cost for the Medical Management of Patients — 581; 661 USD
N/A N=530 FeverText: Assessing Fever Rates After Vaccination During the 2011-12 Influenza Season Using Text Messaging
Fever
Primary: Fever >= 100.4 — 7.5; 37.6; 9.5 percentage of participants
Phase 4 N=221 Fever After Simultaneous Versus Sequential Vaccination in Young Children
Fever After Vaccination · Fever · Febrile Seizure
Primary: Number of Participants With Fever Following Vaccination — 8; 10 Participants — p=0.7588
N/A N=49 FOB in HSCT and Leukemia Patients With Acute Respiratory Symptoms and Pulmonary Infiltrates
Pulmonary Infiltrate New
Primary: Number of Patients With Positive Culture or Molecular Results After Brochoscopy — 40 participants
N/A N=28 Sepsis-Associated Purpura Fulminans International Registry - Europe
Sepsis
Primary: Mortality — 11 Participants
N/A N=203 The Relationship of Defeverscence and Itraconazole Plasma Level Study in Immunocompromised Participants
Hematologic Neoplasms · Neutropenia · Fever
Primary: Percentage of Participants Achieving Plasma Level of Itraconazole at 1000 Nanogram Per Milliliter (ng/mL) or Higher After Administration of Study Treatment — 68.0…
Phase 2 N=741 Dose Finding Study of Fluticasone Furoate Nasal Spray for Uncomplicated Acute Rhinosinusitis
Sinusitis, Acute
Primary: Mean Change From Baseline in the Daily Major Symptom Score (MSS) Over the Entire Treatment Period (Weeks 1-2) — -2.97; -3.36; -3.33 units on a scale — p=0.008
N/A N=60 Validation of the Masimo INVSENSOR00063 in Febrile and Afebrile Subejcts
Fever
Primary: Accuracy of Temperature Measurements Using Masimo INVSENSOR00063 — -0.24; 0.85; 0.05 Degrees Celsius
Phase 4 N=41 Effects of Intravenous Acetaminophen on Body Temperature and Hemodynamic Responses in Febrile Critically Ill Adults
Fever · Critical Illness
Primary: Core Body Temperature — 38.4; 37.9 degrees Celsius — p=0.002
N/A N=264 Observational Non-Interventional Study Of Febrile Neutropenia Patients To Evaluate Antibacterial Therapeutical Options
Febrile Neutropenia
Primary: Percentage of Participants Receiving Antibacterial Agents Preferred by the Turkish Centers Monitoring Febrile Neutropenia (FEN) in Their Therapeutical Approach…
Phase 4 N=60 Ibuprofen Alone and in Combination With Acetaminophen for Treatment of Fever
Fever
Primary: Child Temperature (Degrees C)Over 6 Hours — 38.5; 37.2; 36.9 degrees Celcius — p=<0.001
Phase 4 N=90 Annual Study for Collection of Serum Samples in Children and Older Adults Receiving the 2021-2022 Formulations of Fluzone Quadrivalent Vaccine and Fluzone High-Dose Quadrivalent Vaccine, Respectively
Influenza Immunization · Healthy Volunteers
Primary: Number of Participants Aged 6 Months to <9 Years Who Provided Serum Samples for Analysis: Groups 1 and 2 — 28; 31; 20; 31 Participants
N/A N=10 Novel Blood Test to Predict Safe Foods for Infants and Toddlers With Food Protein-induced Enterocolitis Syndrome (FPIES)
Food Protein-Induced Enterocolitis Syndrome · Allergies · Pediatric Disorder
Primary: Negative Predictive Value (NPV), Defined as the Percentage of Test-predicted Safe Foods That Are Actually Safe Foods. — 98.5; 73.16 percentage — p=<0.0001
Phase 2 N=256 Aggressive Antipyretics for Fever Reduction in CNS Malaria
Malaria · Seizures · Coma
Primary: Mean Maximum Temperature — 38.6; 39.2 degrees of Celsius — p=<0.0001
Phase 2 N=15 Permeability Factor in Focal Segmental Glomerulosclerosis
Focal Segmental Glomerulosclerosis
Primary: Reduction in Proteinuria in Recurrent FSGS Following Renal Transplant With Plasma Exchange and Cyclophosphamide. — 0; 0; 0.5; 0.25 proportion of participants with…
N/A N=1,918 FluSAFE: Flu SMS Alerts to Freeze Exposure
Influenza · Acute Respiratory Infection · Influenza-like Illness
Primary: Number of Laboratory-confirmed Influenza Infections — .22; .14 infections
Phase 2 N=47 Efficacy of Bromocriptine For Fever Reduction in Acute Neurologic Injury
Subarachnoid Hemorrhage · Subdural Hematoma · Traumatic Brain Injury
Primary: Temperature Burden — 37.8; 37.7 Temperature in degrees Celsius
N/A N=323 Caspofungin or Micafungin as Empiric Antifungal Therapy for Persistent Fever and Neutropenia
Febrile Neutropenia
Primary: Composite Primary Endpoint: Number of Participants With an Overall Favorable Response to Echinocandin Therapy for Empiric Antifungal Therapy for Persistent Febrile…
Phase 2 N=61 Urticaria Facticia Treatment With Omalizumab (UFO)
Symptomatic Dermographism
Primary: Change in Provocation Thresholds From Baseline to Day 70 in Urticaria Factitia Patients After Treatment With Omalizumab Compared to Placebo — -1.8; -2.0; -0.6 wheal…
N/A N=62 Procalcitonin Levels in Patients With Fever and a Central Line
Fever
Primary: Procalcitonin Level at ED Presentation — 18.47; 0.65 ng/dL — p=0.001
N/A N=224 FUnctional diagnoSIs of corONary Stenosis (FUSION)
Coronary Artery Disease · Coronary Stenosis
Primary: Sensitivity and Specificity of Virtual Flow Reserve (VFR) Against Fractional Flow Reserve (FFR) — 82; 136 vessels
N/A N=170 Calibration and Validation of the Masimo Temperature Device in Febrile Patients
Fever
Primary: Accuracy of Masimo RAD-GT Temperature Measurments — -0.24; 0.85; 0.09 Degrees Celsius
Phase 2 N=4 Study of Safety, Tolerability and Efficacy of DFV890 in Participants With Familial Cold Auto-inflammatory Syndrome (FCAS)
Familial Cold Autoinflammatory Syndrome
Primary: Ratio of Fold Change From Pre-challenge to the Highest Post-challenge Value of White Cell Count (WCC) Between Treatment and Screening Period — 0.82 ratio of fold change
Phase 2 N=14 Rilonacept for Treatment of Familial Mediterranean Fever (FMF)
Familial Mediterranean Fever
Primary: To Assess the Efficacy of Rilonacept in Decreasing the Number of Acute FMF Attacks. — 0.77; 2.00 number of attacks per month — p=0.027