N/A N=235 Education for Prevention and Treatment of Frailty
Frailty · Frail Elderly Syndrome
Primary: Evaluation of the Change of Baseline Fried Frailty Criteria at 6 Months — 2.3; 1.4 scores on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=141 Metformin for Preventing Frailty in High-risk Older Adults
Frailty
Primary: Frailty Index Based on Deficit Accumulation — -0.0002; 0.0002 Index score
N/A N=65 Does Pulmonary Rehabilitation Improve Frailty?
Disease, Pulmonary
Primary: Number of Participants With Frailty Phenotype at Baseline and 6 Months — 24; 15 Participants — p=0.62
Phase 2 N=16 Ghrelin Plus Strength Training in Frail Elderly Study
Frailty Syndrome
Primary: Change in the Short Physical Performance Battery (SPPB) — 0.6; 2.4 units on a scale
Phase 2 N=5 Ghrelin Dose Finding In Frail Elderly
The Frailty Syndrome
Primary: Treatment Emergent Adverse Events — 1; 0; 1; 0 Events
Phase 2 N=5 Ghrelin Repeated Dose Study
Frailty in Aging
Primary: Safety — 4 participants
N/A N=20 Effect of Behavioral Lifestyle Intervention on Frailty in Older Adults With Diabetes
Frailty · Weight, Body · Type 2 Diabetes
Primary: Frailty Scale Using Fried's Phenotype Method Based on Five Frailty Characteristics — 1.61; 0.94 score on a scale — p=0.01
N/A N=511,285 Development and Validation of a Preoperative Frailty Index Using Health Administrative Data
Frail Elderly Syndrome · Surgery · Outcomes
Primary: Survival for One Year After Surgery — 396164; 0 Participants
N/A N=14 Chronic Kidney Disease Among Frail Elderly
Chronic Kidney Disease
Primary: Mortality — 0; 0 percentage of mortality
N/A N=42 FrAilty Care and wEll-funcTion in Community Dwelling Older Adults
Frailty · Sarcopenia · Aging
Primary: Pilot Evaluation - Percentage of Participants Retained at Follow up — 10; 10; 9; 11 Participants
N/A N=12 Metabolic Syndrome and Fall Risk
Metabolic Syndrome · Autonomic Neuropathy
Primary: Four Square Step Test (FSST) — 11.04; 14.29 seconds
N/A N=459 SUPPORT FOR FRAIL ELDERLY PERSONS - From Prevention to Palliation
Frail Elderly Persons
Primary: Dependence in Two or More Activities of Daily Living (ADL) — 35; 26; 44 participants — p=<0.05
N/A N=204 Vitamin D Levels in Frail Elderly Patients With a Hip Fracture
Hip Fracture · Vitamin D Deficiency
Primary: Number of Participants With Suboptimal and Optimal Levels of Vitamin D (Serum-25(OH)D) — 106; 42; 15; 41 Participants
N/A N=66 Effects of Tai Chi on Frailty in Elderly Adults
Frailty
Primary: Frailty Index — 7; 5; 16; 21 participants — p=0.15
Phase 4 N=100 Antidepressant Response in the Treatment of Depressive Symptoms and Frailty Characteristics in Older Adults
Major Depressive Disorder · Dysthymic Disorder · Depressive Disorder, NOS
Primary: Hamilton Rating Scale for Depression (HRSD) — 13.3 score on a scale
N/A N=40 Assessment of Body Composition and Physical Function
Body Composition · Physical Function
Primary: Fat Mass — 44.71 Kg
Phase 3 N=25 Exercise and Testosterone Therapy in Elderly Men With Physical Frailty
Physical Frailty · Hip Fracture · Elective Hip Replacement
Primary: Mean Change in Total Lean Body Mass — 0.5; 2.3 kg — p=0.01
N/A N=81 LIFT Intervention in Liver Transplant Candidates
Frailty · Cirrhosis · Liver Transplant
Primary: Frailty — 3.63; 3.48 score on a scale
N/A N=15 FRailty WAlking Patterns (FRAP) Study
Heart Failure
Primary: Correlation of Gait Speed Between Reveal LINQ Accelerometer, Validation Accelerometer and/or Computer Assisted Rehabilitation System by Walking Exercises — 0.97; 0.93…
Phase 2 N=14 Reducing Frailty for Older Cancer Survivors Using Supplements
Frailty · Inflammation
Primary: Recruitment Feasibility: Rates of Consent — 0.375 proportion of participants
N/A N=11 Prescribe Exercise for Prevention of Falls and Fractures: A Family Health Team Approach
Fall and Fractures Prevention
Primary: Physical Activity (Reporting Change in Physical Activity From Baseline to Six-week Follow-up) — 21.6 minutes/day
Phase 2 N=120 Metformin and Muscle in Insulin-resistant Older Veterans
Prediabetes
Primary: Change in Total Lean Mass From Baseline — 322.8; 697.6; 392.4; 548.0 grams lean mass — p=0.45
N/A N=32 Frail2Fit Study: Online Nutrition and Exercise Support for Older Adults With Frailty
Frailty · Malnutrition · Sedentary Behavior
Primary: Volunteers Trained — 5 Participants
N/A N=181 Continuum of Care for Frail Elderly People
Frail Elderly People
Primary: Health Care Consumption
Phase 2 N=65 AllogeneiC Human Mesenchymal Stem Cells (hMSC) in Patients With Aging FRAilTy Via IntravenoUS Delivery
Frailty
Primary: Incidence of Any Treatment Emergent - Serious Adverse Events (TE-SAEs) — 0; 0; 0; 0 Incidents
N/A N=45 CogXergaming to Promote Physical Activity and Cognitive Function in Frail Older Adults
Frail Older Adults
Primary: Change in 30-second Chair Stand Performance — 10.28; 12.11; 12.36; 12.30 number of repetitions
N/A N=1,139 Working to Increase Stability Through Exercise
Fractures, Bone · Serious Fall-related Injuries
Primary: Number of Participants Experiencing a Serious Fall-Related Injury (SFI) — 186; 166 Participants — p=0.43
N/A N=10 Pilot of Cognitive Stimulation Therapy for Pre-frail Stroke Survivors
Stroke · Frailty · Carers
Primary: Framework Analysis Using the Theoretical Framework of Acceptability as a Guiding Framework — 4; 4; 4; 4 Participants
N/A N=255 Analysis of the Relationship Between Early Postoperative Anemia and the Evolution of Autonomy at 6 Months in Patients 75 Years of Age and Older Operated on Following a Fracture of the Upper End of the Femur
Femoral Fracture
Primary: Hemoglobin Rate — 10 g/dl
N/A N=21 Exercise Snacking to Improve Strength and STability: ESISST Pilot Study
Acceptability of an Exercise Intervention
Primary: Acceptability of the Intervention — 4.6 score on a scale