Phase 4 N=41 EMD and/or Bone Substitute for the Treatment of Class II Furcations
Periodontal Disease
Primary: Relative Horizontal Clinical Attachment Level (RHCAL) at 12 Months — 2.31; 3.00; 2.57 mm
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=33 Effect of Laser Use on Guided Tissue Regeneration in Treatment of Molar Teeth With Class 2 Furcation Affected by Periodontitis
Furcation Defects · Periodontitis · Alveolar Bone Loss Beyond Furcation
Primary: Change in Clinical Attachment( Gain or Loss) Measured by Horizontal Clinical Attachment Loss(in mm) From Baseline to 6 Months. — -.82; -1.26 mm
N/A N=36 In Vivo Assessment of the Tooth-Resin Composite Interface Using Optical Coherence Tomography
Cavity · Cavities of Teeth
Primary: Marginal Staining: World Dental Federation (FDI) Criteria - Baseline — 18; 18; 0; 0 Participants
N/A N=30 Effectiveness of Modified-free Gingival Graft for Treatment of Localized Gingival Recession Defects
Gingival Recession, Localized
Primary: Mean Mid-facial Recession Coverage (mRC) — 60.7; 91.8 percentage
N/A N=41 Clinical and Radiographic Evaluation of Demineralized Freeze-Dried Bone Allograft Versus Platelet Rich Fibrin for the Treatment of Periodontal Intrabony Defects in Humans
Periodontitis
Primary: Change in Clinical Attachment Level (CAL) — 1.21; 1.03 mm
N/A N=40 Platelet-rich Fibrin and Connective Tissue Graft in Recession Treatment
Gingival Recession
Primary: Vertical Recession — 3.35; 3.20; 0.38; 0.65 mm — p=0.259
N/A N=180 Morphological Pattern of the Atrophic Posterior Maxillae
Bone Deficiency, Posterior Maxillae
Primary: Lateral Wall Thickness — 161 mm
Phase 3 N=983 Prevention of Adult Caries Study (PACS)
Caries, Dental
Primary: Total Net D12FS Caries Increment (Total of Non-cavitated Lesions (D1), Cavitated Lesions (D2) and Sound Surfaces (S)) — 2.43; 2.68 weighted increment units/13 months…
N/A N=15 A New Therapeutic Approach for Root Coverage
Gingival Recession
Primary: Percentage of Root Coverage — 66; 73 percentage of area covered
N/A N=20 Single Stage Root Coverage for Gingival Recession With or Without Free Gingival Graft
Gingival Recession
Primary: Recession Height — 1.0; 0.9 mm
N/A N=38 NCCL Direct Composite Restoration Performance With Self-Etch and Multimode Adhesives
Dental Adhesives/Restorations Performance
Primary: Esthetic, Functional and Biological Clinical Performance Adhesive/Adhesion Mode of NCCLs Restoration, Graded on a 5-point Scale, Using FDI Criteria at 24 Month Follow-up…
N/A N=51 Treatment of Interproximal Cavities on Primary Molar Teeth With Silver Diamine Fluoride
Dental Caries in Children · Dental Caries Class II · Dental Caries
Primary: Interproximal Caries Zone of Radiolucency — 9; 7; 10; 12 Number of teeth
Phase 2 N=70 Self Assembling Peptide P11-4 in Patients With Early Occlusal Carious Lesions
Dental Caries
Primary: Caries Activity and Progression Assessment Using LASER Fluorescence Readings by Diagnodent® Device. — 18.6; 1.1 units on a scale
N/A N=50 Curved Soft-Picks on Plaque Accumulation on Patients With Gingivitis
Gingivitis
Primary: Change in Interproximal Plaque by Modification of the Quigley-Hein Plaque Index at 14 Days — 0.03; -0.07 score on a scale
N/A N=40 A New Surgical-restorative Approach to Treat Gingival Recessions Associated With Non-carious Cervical Lesions (NCCL)
Gingival Recession · Tooth Abrasion
Primary: Percentage of Defect Coverage — 15; 14 Gingival recessions
N/A N=50 Clinical Investigation of the F-Composite 2 System in Direct Filling Therapy
Dental Caries · Unsatisfactory or Defective Restoration of Tooth
Primary: Percentage of Restored Teeth With Postoperative Sensitivity — 7 percentage restored hypersensitive teeth
N/A N=214 Outcome of Coronary High Angulated Bifurcation Lesions Treated With Kissing Ballooning or Sequential Ballooning Techniques
Stable Angina
Primary: Percentage of Participants With Major Adverse Cardiac Events(MACE) — 1.72; 6.86 percentage of participants
N/A N=20 Comparison of Autogenous Periosteal Pedicle Graft and Collagen Membrane in Management of Periodontal Intrabony Defects
Chronic Periodontitis
Primary: Clinical Attachment Level — 6.42; 6.15; 3.52; 3.6 mm
N/A N=60 Platelet Rich Fibrin vs Sub Epithelial Connective Tissue and Coronally Advanced Flap Alone in Gingival Recession
Gingival Recession
Primary: Gingival Thickness — 1.97; 1.95; 1.39 millimeter
Phase 4 N=17 Treatment of Post-Extraction Dehisced Socket - A Case Series Study
Tooth Loss
Primary: Bone Volumetric Reduction From Baseline to 20 Weeks Post-extraction — 73.26 mm3
N/A N=42 Resin Infiltration to Arrest Early Tooth Decay
Dental Caries
Primary: Number of Lesions With Progression as Measured by Pairwise (PW) Comparison (N=Lesions) — 4; 14 Lesions — p==0.003
N/A N=50 Nobio Clinical Study - Demineralization Prevention With a New Antibacterial Restorative Composite
Dental Caries · Denture, Partial, Removable
Primary: Mineral Loss ΔZ — 235; 774 vol% * μm]
N/A N=17 Radiographic Progression of Infiltrated Caries Lesions In-vivo
Dental Caries
Primary: Number of Lesions Showing Radiographic Progression as Measured by Lesion Size (Continuous) — 2; 11 Lesions — p=0.002
N/A N=120 Fissure Caries Inhibition Study With Solea CO2-9.3μm Short-pulsed Laser
Dental Caries
Primary: International Caries Detection and Assessment System (ICDAS II) - Number of Molars With ICDAS Score of 3 or More - ICDAS Score 3, Cavity - — 0; 13 right or left second…
N/A N=38 The Effects of Dis/Reconnection of Implant Abutments on Peri-implant Bone Levels
Bone Loss · Implant Complication · Gingival Recession
Primary: Changes in Peri-implant Marginal Bone Level Between Baseline (Implant Placement) and 1 Year Follow up — 0.80; 0.32 millimeters — p=0.009
N/A N=61 Periimplant Mucosa Dynamics Around Divergent and Concave Atlantis Abutment Transition Profiles
Dental Implant, Single-Tooth · Esthetics, Dental
Primary: Peri-Implant Mucosal Zenith Distance (in Millimeters) at the Concave/Divergent Abutment Sites — 9.860; 9.770; 9.684; 9.618 millimeters
N/A N=32 Zirconia Based Fixed Dental Prostheses
Zirconia Based Fixed Dental Prostheses
Primary: Number of Fixed Dental Prostheses (FDPs) With Failure — 0; 1 FDPs with failure
N/A N=42 Comparison of Two Flaps for Root Coverage
Gingival Recession
Primary: Percentage of Defect Coverage — 87.2; 77.4 percentage of root coverage
N/A N=28 Use of Platelet Rich Fibrin in Addition to CAF and SCTG for Treatment of Gingival Recession
Gingival Recession
Primary: Recession Depth — 2; 2; 0; 0 length in millimeters
N/A N=4 Amnion-Chorion Allograft Barrier Used for Root Surface and Guided Tissue Regeneration
Periodontal Diseases
Primary: Probing Depth Change — 4.22 millimeter