N/A N=32 Induced Gingivitis & Intra-oral Imaging
Plaque Induced Gingivitis
Primary: Change From Baseline Gingivitis at Day 14 as Measured by Non-invasive Microimaging and Gingival Index. — 0.6; 0.15 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=96 Safety and Efficacy of Gintuit(TM)for Oral Soft Tissue Regeneration
Gingival Recession
Primary: Percentage of Subjects With at Least 2 mm Keratinized Tissue (KT) at 6 Months at the Gintuit Treated Site. — 95.3 percentage of participants — p=<0.0001
Phase 3 N=39 Collection of Gingival Crevicular Fluid From Periodontitis Patients
Gingival Diseases
Primary: Metabolite Associated With Inflammation (Cadaverine) — 1.119186; 0.92077 ion count — p=<0.05
Phase 4 N=49 Compare Anti-inflammatory Dentifrices
Gingivitis
Primary: Gingival Index (GI) — 1.04; 1.01 units on a scale — p=<0.05
N/A N=14 To Compare Free Gingival Grafts and Connective Tissue Grafts Around Implants With Lack of Keratinized Mucosa
Dental Implants · Alveolar Mucosa
Primary: The Increase in Keratinized Mucosa (in mm) Between the Two Grafts — 3.29; 1.29 mm
N/A N=27 Implant Placement With Simultaneous Gum Grafting
Edentulous
Primary: Soft Tissue Thickness Over the Implant — 0.6; 0.4 mm
N/A N=69 IFI16 is a Periodontitis Modulating Protein
Severe Periodontitis · Acute Inflammatory Response
Primary: Change in Absent in Melanoma 2 (AIM2) mRNA Expression Levels — 0.37; 0.65 fold change — p=0.3
N/A N=30 Xenogeneic Collagen Matrix as an Alternative to Free Gingival Grafting for Oral Soft Tissue Augmentation
Gingival Diseases
Primary: Keratinized Tissue Width — 4.42; 2.92 mm — p=<0.0001
N/A N=44 Expression of Angiogenic Biomarkers During Healing of Intra-Oral Soft Tissue Engineered Grafts
Gingival Recession
Primary: Differences in Angiogenic Biomarkers — 0.51; .69; 1.04; .67 ng/mL
N/A N=48 Gingival Bleeding and Von Willebrand Disease Typ 2 and 3
Gingival Bleeding · Von Willebrand Diseases
Primary: Bleeding on Probing (BOP) — 14.5; 12.3 percentage of sites
N/A N=60 Platelet Rich Fibrin vs Sub Epithelial Connective Tissue and Coronally Advanced Flap Alone in Gingival Recession
Gingival Recession
Primary: Gingival Thickness — 1.97; 1.95; 1.39 millimeter
N/A N=61 Periimplant Mucosa Dynamics Around Divergent and Concave Atlantis Abutment Transition Profiles
Dental Implant, Single-Tooth · Esthetics, Dental
Primary: Peri-Implant Mucosal Zenith Distance (in Millimeters) at the Concave/Divergent Abutment Sites — 9.860; 9.770; 9.684; 9.618 millimeters
N/A N=28 Use of Platelet Rich Fibrin in Addition to CAF and SCTG for Treatment of Gingival Recession
Gingival Recession
Primary: Recession Depth — 2; 2; 0; 0 length in millimeters
Phase 2 N=71 Safety and Tolerability of Antiplaque Chewing Gum in a Gingivitis Population
Plaque · Gingivitis
Primary: Safety and Tolerability of KSL-W as Measured by Soft Tissue Erythema, Ulceration and Sloughing (AEs and SAEs) — 2; 1; 4; 2 Participants
N/A N=20 Single Stage Root Coverage for Gingival Recession With or Without Free Gingival Graft
Gingival Recession
Primary: Recession Height — 1.0; 0.9 mm
N/A N=42 Evaluation of the Treatment of Multiple Gingival Recession Using Modified Coronally Advanced Tunnel With Subepithelial Connective Tissue Graft Depending on the Positioning of the Graft
Gingival Recession
Primary: Percent Change in Gingival Recession (Mean Root Coverage, MRC) — 95.00; 96.00 Percent change (%)
N/A N=15 To Compare Two Commonly Used Soft Tissue Grafting Techniques to Achieve Coronal Flap Advancement and Root Coverage
Gingival Recession
Primary: KT Width at 6 Month Following Grafting With VISTA and Sulcular Tunnel Access With ADM — 3.15; 2.23 mm
N/A N=19 Clinical and Histological Outcomes of Allogenic Amnion Chorion Membrane in the Healing of Free Gingival Graft Donor Site
Palatal Wound
Primary: Size of Wound Area — 80; 80 micrometers (μm)
N/A N=40 Platelet-rich Fibrin and Connective Tissue Graft in Recession Treatment
Gingival Recession
Primary: Vertical Recession — 3.35; 3.20; 0.38; 0.65 mm — p=0.259
N/A N=34 Effect of Non-surgical Periodontal Therapy on Gingival Crevicular Fluid Interleukin-21 Levels
Chronic Peridontitis Patients · Chronic Gingivitis · Healthy
Primary: Pocket Depth — 1.60; 2.50; 6.75 millimetres
N/A N=4 Amnion-Chorion Allograft Barrier Used for Root Surface and Guided Tissue Regeneration
Periodontal Diseases
Primary: Probing Depth Change — 4.22 millimeter
Phase 4 N=113 Relationship of Periodontal Disease Treatment and Type 2 Diabetes Mellitus in the Gullah Population
Periodontal Disease · Type 2 Diabetes Mellitus
Primary: Glycated Hemoglobin A1c — 8; 8.2 percentage of Glycated Hemoglobin A1c
Phase 3 N=15 Train New Examiners Via Modified Gingival Margin Plaque
Dental Plaque
Primary: Mean Gingival Plaque Units — 13.38; 14.29 Units on a scale — p=0.05
N/A N=34 Patient Outcomes and Gingival Blood Flow Using Laser Doppler Flowmetry Following the Use of Episil on Free Gingival Graft Donor Sites
Pain From Free Gingival Graft
Primary: Postoperative Pain as Assessed by Number of Participants With a Score of 0-3 (no to Minimal Pain) on a Visual Analog Scale — 12; 6 Participants — p=0.039
Phase 3 N=19 Investigation of Dental Plaque and Gingival Index
Dental Plaque
Primary: Gingival Margin Plaque Index — 15.4; 12.81 Units on a scale — p=0.05
Phase 4 N=20 Comparison of Two Different Surgical Approaches To Increase Peri-Implant Mucosa Thickness
Tooth Loss · Peri-implant Mucosa Defect
Primary: Change in Buccal Peri-implant Mucosa Thickness Between Baseline and 16 Weeks After Surgery — 0.44; 0.05 millimeters
N/A N=40 A New Surgical-restorative Approach to Treat Gingival Recessions Associated With Non-carious Cervical Lesions (NCCL)
Gingival Recession · Tooth Abrasion
Primary: Percentage of Defect Coverage — 15; 14 Gingival recessions
N/A N=41 Case Selection and Treatment Protocol for Immediate Dental Implants in the Esthetic Zone
Jaw, Edentulous, Partially · Acquired Absence of Single Tooth
Primary: Mid Facial Mucosal Level at Implant Site — 0.36; 0.49 mm
N/A N=38 Assessing Effects of a Denture Gel on Gum Abrasions
Gum Injury
Primary: Abrasion Assessment (Number) — 3.65; 4.11 number of abrasions
N/A N=72 To Measure Pain Perception Following De-Epithelized Free Gingival Graft Harvesting
Gingival Recession · Palate; Wound
Primary: Pain Assessment (0=No Pain to 10=Worst) — 4.2; 1.9; 2.2; 1 score on a scale